Genetic and Transcriptomic Biomarkers in Neurodegenerative Diseases: Current Situation and the Road Ahead

por Lake, Julie, Storm, Catherine S., Makarious, Mary B., Bandres-Ciga, Sara
Publicado 2021

Federated Learning for multi-omics: a performance evaluation in Parkinson’s disease

por Danek, Benjamin, Makarious, Mary B., Dadu, Anant, Vitale, Dan, Nalls, Mike A, Sun, Jimeng, Faghri, Faraz
Publicado 2023

PTPA variants and the risk for Parkinson’s disease in diverse ancestry populations

por Ostrožovičová, Miriam, Mecheri, Yasser, Al-Mubarak, Bashayer R, Al-Tassan, Nada, Makarious, Mary B, Periñan, Maria Teresa, Bandres-Ciga, Sara
Publicado 2023

A population scale analysis of rare SNCA variation in the UK Biobank

por Blauwendraat, Cornelis, Makarious, Mary B., Leonard, Hampton L., Bandres-Ciga, Sara, Iwaki, Hirotaka, Nalls, Mike A., Noyce, Alastair J., Singleton, Andrew B.
Publicado 2020

RIC3 variants are not associated with Parkinson’s disease in large European, Latin American, or East Asian cohorts

por Brolin, Kajsa, Bandres-Ciga, Sara, Leonard, Hampton, Makarious, Mary B., Blauwendraat, Cornelis, Mata, Ignacio F, Foo, Jia Nee, Pihlstrøm, Lasse, Swanberg, Maria, Gan-Or, Ziv, Tan, Manuela MX
Publicado 2022

omicSynth: an Open Multi-omic Community Resource for Identifying Druggable Targets across Neurodegenerative Diseases

por Alvarado, Chelsea X., Makarious, Mary B., Weller, Cory A., Vitale, Dan, Koretsky, Mathew J., Bandres-Ciga, Sara, Iwaki, Hirotaka, Levine, Kristin, Singleton, Andrew, Faghri, Faraz, Nalls, Mike A., Leonard, Hampton L.
Publicado 2023

The Parkinson's Disease DNA Variant Browser

por Kim, Jonggeol J., Makarious, Mary B., Bandres‐Ciga, Sara, Gibbs, Jesse Raphael, Ding, Jinhui, Hernandez, Dena G., Brooks, Janet, Grenn, Francis P., Iwaki, Hirotaka, Singleton, Andrew B., Nalls, Mike A., Blauwendraat, Cornelis
Publicado 2021

Genetic risk factor clustering within and across neurodegenerative diseases

por Koretsky, Mathew J, Alvarado, Chelsea, Makarious, Mary B, Vitale, Dan, Levine, Kristin, Bandres-Ciga, Sara, Dadu, Anant, Scholz, Sonja W, Sargent, Lana, Faghri, Faraz, Iwaki, Hirotaka, Blauwendraat, Cornelis, Singleton, Andrew, Nalls, Mike, Leonard, Hampton
Publicado 2023

Polygenic Resilience Modulates the Penetrance of Parkinson Disease Genetic Risk Factors

por Liu, Hui, Dehestani, Mohammad, Blauwendraat, Cornelis, Makarious, Mary B., Leonard, Hampton, Kim, Jonggeol J., Schulte, Claudia, Noyce, Alastair, Jacobs, Benjamin M., Foote, Isabelle, Sharma, Manu, Nalls, Mike, Singleton, Andrew, Gasser, Thomas, Bandres‐Ciga, Sara
Publicado 2022

Long-read sequencing resolves a complex structural variant in PRKN Parkinson’s disease

por Daida, Kensuke, Funayama, Manabu, Billingsley, Kimberley J, Malik, Laksh, Miano-Burkhardt, Abigail, Leonard, Hampton L., Makarious, Mary B., Iwaki, Hirotaka, Ding, Jinhui, Gibbs, J. Raphael, Ishiguro, Mayu, Yoshino, Hiroyo, Ogaki, Kotaro, Oyama, Genko, Nishioka, Kenya, Nonaka, Risa, Akamatsu, Wado, Blauwendraat, Cornelis, Hattori, Nobutaka
Publicado 2023

Exploring the genetic and genomic connection underlying neurodegeneration with brain iron accumulation and the risk for Parkinson’s disease

por Alvarez Jerez, Pilar, Alcantud, Jose Luis, de los Reyes-Ramírez, Lucia, Moore, Anni, Ruz, Clara, Vives Montero, Francisco, Rodriguez-Losada, Noela, Saini, Prabhjyot, Gan-Or, Ziv, Alvarado, Chelsea X., Makarious, Mary B., Billingsley, Kimberley J., Blauwendraat, Cornelis, Noyce, Alastair J., Singleton, Andrew B., Duran, Raquel, Bandres-Ciga, Sara
Publicado 2023

Identification and prediction of Parkinson’s disease subtypes and progression using machine learning in two cohorts

por Dadu, Anant, Satone, Vipul, Kaur, Rachneet, Hashemi, Sayed Hadi, Leonard, Hampton, Iwaki, Hirotaka, Makarious, Mary B., Billingsley, Kimberley J., Bandres‐Ciga, Sara, Sargent, Lana J., Noyce, Alastair J., Daneshmand, Ali, Blauwendraat, Cornelis, Marek, Ken, Scholz, Sonja W., Singleton, Andrew B., Nalls, Mike A., Campbell, Roy H., Faghri, Faraz
Publicado 2022

Multi-ancestry meta-analysis and fine-mapping in Alzheimer’s disease

por Lake, Julie, Warly Solsberg, Caroline, Kim, Jonggeol Jeffrey, Acosta-Uribe, Juliana, Makarious, Mary B., Li, Zizheng, Levine, Kristin, Heutink, Peter, Alvarado, Chelsea X., Vitale, Dan, Kang, Sarang, Gim, Jungsoo, Lee, Kun Ho, Pina-Escudero, Stefanie D., Ferrucci, Luigi, Singleton, Andrew B., Blauwendraat, Cornelis, Nalls, Mike A., Yokoyama, Jennifer S., Leonard, Hampton L.
Publicado 2023

Accelerating Medicines Partnership: Parkinson's Disease. Genetic Resource

por Iwaki, Hirotaka, Leonard, Hampton L., Makarious, Mary B., Bookman, Matt, Landin, Barry, Vismer, David, Casey, Bradford, Gibbs, J. Raphael, Hernandez, Dena G., Blauwendraat, Cornelis, Vitale, Daniel, Song, Yeajin, Kumar, Dinesh, Dalgard, Clifton L., Sadeghi, Mahdiar, Dong, Xianjun, Misquitta, Leonie, Scholz, Sonja W., Scherzer, Clemens R., Nalls, Mike A., Biswas, Shameek, Singleton, Andrew B.
Publicado 2021

Genome-wide case-only analysis of gene-gene interactions with known Parkinson’s disease risk variants reveals link between LRRK2 and SYT10

por Aleknonytė-Resch, Milda, Trinh, Joanne, Leonard, Hampton, Delcambre, Sylvie, Leitão, Elsa, Lai, Dongbing, Smajić, Semra, Orr-Urtreger, Avi, Thaler, Avner, Blauwendraat, Cornelis, Sharma, Arunabh, Makarious, Mary B., Kim, Jonggeol Jeff, Lake, Julie, Rahmati, Pegah, Freitag-Wolf, Sandra, Seibler, Philip, Foroud, Tatiana, Singleton, Andrew B., Grünewald, Anne, Kaiser, Frank, Klein, Christine, Krawczak, Michael, Dempfle, Astrid
Publicado 2023

Defining the causes of sporadic Parkinson’s disease in the global Parkinson’s genetics program (GP2)

por Towns, Clodagh, Richer, Madeleine, Jasaityte, Simona, Stafford, Eleanor J., Joubert, Julie, Antar, Tarek, Martinez-Carrasco, Alejandro, Makarious, Mary B., Casey, Bradford, Vitale, Dan, Levine, Kristin, Leonard, Hampton, Pantazis, Caroline B., Screven, Laurel A., Hernandez, Dena G., Wegel, Claire E., Solle, Justin, Nalls, Mike A., Blauwendraat, Cornelis, Singleton, Andrew B., Tan, Manuela M. X., Iwaki, Hirotaka, Morris, Huw R.
Publicado 2023

The Parkinson's Disease Genome‐Wide Association Study Locus Browser

por Grenn, Francis P., Kim, Jonggeol J., Makarious, Mary B., Iwaki, Hirotaka, Illarionova, Anastasia, Brolin, Kajsa, Kluss, Jillian H., Schumacher‐Schuh, Artur F., Leonard, Hampton, Faghri, Faraz, Billingsley, Kimberley, Krohn, Lynne, Hall, Ashley, Diez‐Fairen, Monica, Periñán, Maria Teresa, Foo, Jia Nee, Sandor, Cynthia, Webber, Caleb, Fiske, Brian K., Gibbs, J. Raphael, Nalls, Mike A., Singleton, Andrew B., Bandres‐Ciga, Sara, Reed, Xylena, Blauwendraat, Cornelis
Publicado 2020

Multi-modality machine learning predicting Parkinson’s disease

por Makarious, Mary B., Leonard, Hampton L., Vitale, Dan, Iwaki, Hirotaka, Sargent, Lana, Dadu, Anant, Violich, Ivo, Hutchins, Elizabeth, Saffo, David, Bandres-Ciga, Sara, Kim, Jonggeol Jeff, Song, Yeajin, Maleknia, Melina, Bookman, Matt, Nojopranoto, Willy, Campbell, Roy H., Hashemi, Sayed Hadi, Botia, Juan A., Carter, John F., Craig, David W., Van Keuren-Jensen, Kendall, Morris, Huw R., Hardy, John A., Blauwendraat, Cornelis, Singleton, Andrew B., Faghri, Faraz, Nalls, Mike A.
Publicado 2022

NeuroBooster Array: A Genome-Wide Genotyping Platform to Study Neurological Disorders Across Diverse Populations

por Bandres-Ciga, Sara, Faghri, Faraz, Majounie, Elisa, Koretsky, Mathew J, Kim, Jeffrey, Levine, Kristin S, Leonard, Hampton, Makarious, Mary B, Iwaki, Hirotaka, Crea, Peter Wild, Hernandez, Dena G, Arepalli, Sampath, Billingsley, Kimberley, Lohmann, Katja, Klein, Christine, Lubbe, Steven J, Jabbari, Edwin, Saffie-Awad, Paula, Narendra, Derek, Reyes-Palomares, Armando, Quinn, John P, Schulte, Claudia, Morris, Huw R, Traynor, Bryan J., Scholz, Sonja W., Houlden, Henry, Hardy, John, Dumanis, Sonya, Riley, Ekemini, Blauwendraat, Cornelis, Singleton, Andrew, Nalls, Mike, Jeff, Janina, Vitale, Dan
Publicado 2023

Deficiency in endocannabinoid synthase DAGLB contributes to early onset Parkinsonism and murine nigral dopaminergic neuron dysfunction

por Liu, Zhenhua, Yang, Nannan, Dong, Jie, Tian, Wotu, Chang, Lisa, Ma, Jinghong, Guo, Jifeng, Tan, Jieqiong, Dong, Ao, He, Kaikai, Zhou, Jingheng, Cinar, Resat, Wu, Junbing, Salinas, Armando G., Sun, Lixin, Kumar, Mantosh, Sullivan, Breanna T., Oldham, Braden B., Pitz, Vanessa, Makarious, Mary B., Ding, Jinhui, Kung, Justin, Xie, Chengsong, Hawes, Sarah L., Wang, Lupeng, Wang, Tao, Chan, Piu, Zhang, Zhuohua, Le, Weidong, Chen, Shengdi, Lovinger, David M., Blauwendraat, Cornelis, Singleton, Andrew B., Cui, Guohong, Li, Yulong, Cai, Huaibin, Tang, Beisha
Publicado 2022