Phosphoinositides Decrease Atp Sensitivity of the Cardiac Atp-Sensitive K(+) Channel: A Molecular Probe for the Mechanism of Atp-Sensitive Inhibition

por Fan, Zheng, Makielski, Jonathan C.
Publicado 1999

Vinculin variant M94I identified in sudden unexplained nocturnal death syndrome decreases cardiac sodium current

por Cheng, Jianding, Kyle, John W., Wiedmeyer, Brandi, Lang, Di, Vaidyanathan, Ravi, Makielski, Jonathan C.
Publicado 2017

The interaction of caveolin 3 protein with the potassium inward rectifier channel Kir2.1. PHYSIOLOGY AND PATHOLOGY RELATED TO LONG QT SYNDROME 9 (LQT9).

por Vaidyanathan, Ravi, Vega, Amanda L., Song, Chunhua, Zhou, Qing, Tan, Bi-Hua, Berger, Stuart, Makielski, Jonathan C., Eckhardt, Lee L.
Publicado 2013

Expression defect of the rare variant/Brugada mutation R1512W depends upon the SCN5A splice variant background and can be rescued by mexiletine and the common polymorphism H558R

por Hu, Rou-Mu, Song, Evelyn J., Tester, David J., Deschenes, Isabelle, Ackerman, Michael J., Makielski, Jonathan C., Tan, Bi-Hua
Publicado 2021

The biophysical characterization of the first SCN5A mutation R1512W identified in Chinese sudden unexplained nocturnal death syndrome

por Zheng, Jinxiang, Zhou, Feng, Su, Terry, Huang, Lei, Wu, Yeda, Yin, Kun, Wu, Qiuping, Tang, Shuangbo, Makielski, Jonathan C., Cheng, Jianding
Publicado 2016

An East Asian Common Variant Vinculin P.Asp841His Was Associated With Sudden Unexplained Nocturnal Death Syndrome in the Chinese Han Population

por Cheng, Jianding, Kyle, John W., Lang, Di, Wiedmeyer, Brandi, Guo, Jian, Yin, Kun, Huang, Lei, Vaidyanathan, Ravi, Su, Terry, Makielski, Jonathan C.
Publicado 2017

Transgenic overexpression of the SUR2A-55 splice variant in mouse heart reduces infract size and promotes protective mitochondrial function

por Ramratnam, Mohun, Kenny, Barrett, Kyle, John W., Wiedmeyer, Brandi, Hacker, Timothy A., Barefield, David Y., McNally, Elizabeth M., Makielski, Jonathan C.
Publicado 2018

Mexiletine rescues a mixed biophysical phenotype of the cardiac sodium channel arising from the SCN5A mutation, N406K, found in LQT3 patients

por Hu, Rou-Mu, Tester, David J., Li, Ryan, Sun, Tianyu, Peterson, Blaise Z., Ackerman, Michael J., Makielski, Jonathan C., Tan, Bi-Hua
Publicado 2018

Does Anatomic Phenotype of Mitral Annular Disjunction Impact Survival? An Autopsy-Based Retrospective Study

por Zhou, Nan, Zhao, Qianhao, Li, Rui, Zheng, Da, Xiao, Yuxi, Mao, Danmi, Wang, Yunyi, Yue, Jiacheng, Zhang, Kai, Makielski, Jonathan C., Cheng, Jianding
Publicado 2021

Arrhythmogenic Biophysical Phenotype for SCN5A Mutation S1787N Depends upon Splice Variant Background and Intracellular Acidosis

por Hu, Rou-Mu, Tan, Bi-Hua, Tester, David J., Song, Chunhua, He, Yang, Dovat, Sinisa, Peterson, Blaise Z., Ackerman, Michael J., Makielski, Jonathan C.
Publicado 2015

Mouse ERG K(+) Channel Clones Reveal Differences in Protein Trafficking and Function

por Lin, Eric C., Moungey, Brooke M., Lim, Evi, Concannon, Sarah P., Anderson, Corey L., Kyle, John W., Makielski, Jonathan C., Balijepalli, Sadguna Y., January, Craig T.
Publicado 2014

Deletion of Sulfonylurea Receptor 2 in the Adult Myocardium Enhances Cardiac Glucose Uptake and Is Cardioprotective

por Aubert, Gregory, Barefield, David Y., Demonbreun, Alexis R., Ramratnam, Mohun, Fallon, Katherine S., Warner, James L., Rossi, Ann E., Hadhazy, Michele, Makielski, Jonathan C., McNally, Elizabeth M.
Publicado 2019

Calcium Transients Closely Reflect Prolonged Action Potentials in iPSC Models of Inherited Cardiac Arrhythmia

por Spencer, C. Ian, Baba, Shiro, Nakamura, Kenta, Hua, Ethan A., Sears, Marie A.F., Fu, Chi-cheng, Zhang, Jianhua, Balijepalli, Sadguna, Tomoda, Kiichiro, Hayashi, Yohei, Lizarraga, Paweena, Wojciak, Julianne, Scheinman, Melvin M., Aalto-Setälä, Katriina, Makielski, Jonathan C., January, Craig T., Healy, Kevin E., Kamp, Timothy J., Yamanaka, Shinya, Conklin, Bruce R.
Publicado 2014