Targeted delivery to macrophages and dendritic cells by chemically modified mannose ligand-conjugated siRNA

por Uehara, Keiji, Harumoto, Toshimasa, Makino, Asana, Koda, Yasuo, Iwano, Junko, Suzuki, Yasuhiro, Tanigawa, Mari, Iwai, Hiroto, Asano, Kana, Kurihara, Kana, Hamaguchi, Akinori, Kodaira, Hiroshi, Atsumi, Toshiyuki, Yamada, Yoji, Tomizuka, Kazuma
Publicado 2022

siRNA potency enhancement via chemical modifications of nucleotide bases at the 5′-end of the siRNA guide strand

por Shinohara, Fumikazu, Oashi, Taiji, Harumoto, Toshimasa, Nishikawa, Tomoyuki, Takayama, Yuki, Miyagi, Hikaru, Takahashi, Yuichi, Nakajima, Takahiro, Sawada, Takashi, Koda, Yasuo, Makino, Asana, Sato, Atsuko, Hamaguchi, Kaori, Suzuki, Michihiko, Yamamoto, Junichiro, Tomari, Yukihide, Saito, Jun-Ichi
Publicado 2021