hERG S4-S5 linker acts as a voltage-dependent ligand that binds to the activation gate and locks it in a closed state

por Malak, Olfat A., Es-Salah-Lamoureux, Zeineb, Loussouarn, Gildas
Publicado 2017

Up-regulation of voltage-gated sodium channels by peptides mimicking S4-S5 linkers reveals a variation of the ligand-receptor mechanism

por Malak, Olfat A., Abderemane-Ali, Fayal, Wei, Yue, Coyan, Fabien C., Pontus, Gilyane, Shaya, David, Marionneau, Céline, Loussouarn, Gildas
Publicado 2020

Physiological and Pathophysiological Insights of Nav1.4 and Nav1.5 Comparison

por Loussouarn, Gildas, Sternberg, Damien, Nicole, Sophie, Marionneau, Céline, Le Bouffant, Francoise, Toumaniantz, Gilles, Barc, Julien, Malak, Olfat A., Fressart, Véronique, Péréon, Yann, Baró, Isabelle, Charpentier, Flavien
Publicado 2016

Activation of PDGFRA signaling contributes to filamin C–related arrhythmogenic cardiomyopathy

por Chen, Suet Nee, Lam, Chi Keung, Wan, Ying-Wooi, Gao, Shanshan, Malak, Olfat A., Zhao, Shane Rui, Lombardi, Raffaella, Ambardekar, Amrut V., Bristow, Michael R., Cleveland, Joseph, Gigli, Marta, Sinagra, Gianfranco, Graw, Sharon, Taylor, Matthew R.G., Wu, Joseph C., Mestroni, Luisa
Publicado 2022