Modern Genome Editing Technologies in Huntington’s Disease Research

por Malankhanova, Tuyana B., Malakhova, Anastasia A., Medvedev, Sergey P., Zakian, Suren M.
Publicado 2017

Nanoscale Detonation Carbon Demonstrates Biosafety in Human Cell Culture

por Malakhova, Anastasia A., Rybin, Denis K., Shtertser, Alexandr A., Dudina, Dina V.
Publicado 2022

Oxidative stress monitoring in iPSC-derived motor neurons using genetically encoded biosensors of H(2)O(2)

por Ustyantseva, Elizaveta, Pavlova, Sophia V., Malakhova, Anastasia A., Ustyantsev, Kirill, Zakian, Suren M., Medvedev, Sergey P.
Publicado 2022

A Human Induced Pluripotent Stem Cell-Derived Isogenic Model of Huntington’s Disease Based on Neuronal Cells Has Several Relevant Phenotypic Abnormalities

por Malankhanova, Tuyana, Suldina, Lyubov, Grigor’eva, Elena, Medvedev, Sergey, Minina, Julia, Morozova, Ksenia, Kiseleva, Elena, Zakian, Suren, Malakhova, Anastasia
Publicado 2020

Variability of Sequence Surrounding the Xist Gene in Rodents Suggests Taxon-Specific Regulation of X Chromosome Inactivation

por Shevchenko, Alexander I., Malakhova, Anastasia A., Elisaphenko, Eugeny A., Mazurok, Nina A., Nesterova, Tatyana B., Brockdorff, Neil, Zakian, Suren M.
Publicado 2011

Introducing an expanded CAG tract into the huntingtin gene causes a wide spectrum of ultrastructural defects in cultured human cells

por Morozova, Ksenia N., Suldina, Lyubov A., Malankhanova, Tuyana B., Grigor’eva, Elena V., Zakian, Suren M., Kiseleva, Elena, Malakhova, Anastasia A.
Publicado 2018

Usnic Acid Derivatives Inhibit DNA Repair Enzymes Tyrosyl-DNA Phosphodiesterases 1 and 2 and Act as Potential Anticancer Agents

por Zakharenko, Alexandra L., Dyrkheeva, Nadezhda S., Luzina, Olga A., Filimonov, Aleksandr S., Mozhaitsev, Evgenii S., Malakhova, Anastasia A., Medvedev, Sergey P., Zakian, Suren M., Salakhutdinov, Nariman F., Lavrik, Olga I.
Publicado 2023

New Hybrid Compounds Combining Fragments of Usnic Acid and Monoterpenoids for Effective Tyrosyl-DNA Phosphodiesterase 1 Inhibition

por Dyrkheeva, Nadezhda S., Filimonov, Aleksandr S., Luzina, Olga A., Zakharenko, Alexandra L., Ilina, Ekaterina S., Malakhova, Anastasia A., Medvedev, Sergey P., Reynisson, Jóhannes, Volcho, Konstantin P., Zakian, Suren M., Salakhutdinov, Nariman F., Lavrik, Olga I.
Publicado 2021

Biochemical Characteristics of iPSC-Derived Dopaminergic Neurons from N370S GBA Variant Carriers with and without Parkinson’s Disease

por Grigor’eva, Elena V., Kopytova, Alena E., Yarkova, Elena S., Pavlova, Sophia V., Sorogina, Diana A., Malakhova, Anastasia A., Malankhanova, Tuyana B., Baydakova, Galina V., Zakharova, Ekaterina Y., Medvedev, Sergey P., Pchelina, Sofia N., Zakian, Suren M.
Publicado 2023

Adamantane-Monoterpenoid Conjugates Linked via Heterocyclic Linkers Enhance the Cytotoxic Effect of Topotecan

por Munkuev, Aldar A., Dyrkheeva, Nadezhda S., Kornienko, Tatyana E., Ilina, Ekaterina S., Ivankin, Dmitry I., Suslov, Evgeniy V., Korchagina, Dina V., Gatilov, Yuriy V., Zakharenko, Alexandra L., Malakhova, Anastasia A., Reynisson, Jóhannes, Volcho, Konstantin P., Salakhutdinov, Nariman F., Lavrik, Olga I.
Publicado 2022

Transcriptomic Analysis of CRISPR/Cas9-Mediated PARP1-Knockout Cells under the Influence of Topotecan and TDP1 Inhibitor

por Dyrkheeva, Nadezhda S., Malakhova, Anastasia A., Zakharenko, Aleksandra L., Okorokova, Larisa S., Shtokalo, Dmitriy N., Pavlova, Sophia V., Medvedev, Sergey P., Zakian, Suren M., Nushtaeva, Anna A., Tupikin, Alexey E., Kabilov, Marsel R., Khodyreva, Svetlana N., Luzina, Olga A., Salakhutdinov, Nariman F., Lavrik, Olga I.
Publicado 2023

New Hybrid Compounds Combining Fragments of Usnic Acid and Thioether Are Inhibitors of Human Enzymes TDP1, TDP2 and PARP1

por Dyrkheeva, Nadezhda S., Filimonov, Aleksandr S., Luzina, Olga A., Orlova, Kristina A., Chernyshova, Irina A., Kornienko, Tatyana E., Malakhova, Anastasia A., Medvedev, Sergey P., Zakharenko, Alexandra L., Ilina, Ekaterina S., Anarbaev, Rashid O., Naumenko, Konstantin N., Klabenkova, Kristina V., Burakova, Ekaterina A., Stetsenko, Dmitry A., Zakian, Suren M., Salakhutdinov, Nariman F., Lavrik, Olga I.
Publicado 2021

Design, Synthesis, and Biological Investigation of Novel Classes of 3-Carene-Derived Potent Inhibitors of TDP1

por Il’ina, Irina V., Dyrkheeva, Nadezhda S., Zakharenko, Alexandra L., Sidorenko, Alexander Yu., Li-Zhulanov, Nikolay S., Korchagina, Dina V., Chand, Raina, Ayine-Tora, Daniel M., Chepanova, Arina A., Zakharova, Olga D., Ilina, Ekaterina S., Reynisson, Jóhannes, Malakhova, Anastasia A., Medvedev, Sergey P., Zakian, Suren M., Volcho, Konstantin P., Salakhutdinov, Nariman F., Lavrik, Olga I.
Publicado 2020