Synthesis and Biological Evaluations of NO-Donating Oxa- and Aza-Pentacycloundecane Derivatives as Potential Neuroprotective Candidates

por Sharma, Rajan, Joubert, Jacques, Malan, Sarel F.
Publicado 2018

Design, synthesis and biological evaluation of edaravone derivatives bearing the N-benzyl pyridinium moiety as multifunctional anti-Alzheimer’s agents

por Zondagh, Luke S., Malan, Sarel F., Joubert, Jacques
Publicado 2020

Microwave Optimized Synthesis of N-(adamantan-1-yl)-4-[(adamantan-1-yl)-sulfamoyl]benzamide and Its Derivatives for Anti-Dengue Virus Activity

por Joubert, Jacques, Foxen, Eugene B., Malan, Sarel F.
Publicado 2018

Editorial: Channel Modulation in Neurodegeneration and Neuroprotection

por Joubert, Jacques, Malan, Sarel F., Geldenhuys, Werner J.
Publicado 2022

Tacrine, Trolox and Tryptoline as Lead Compounds for the Design and Synthesis of Multi-target Agents for Alzheimer’s Disease Therapy

por Teponnou, Gerard A. K., Joubert, Jacques, Malan, Sarel F.
Publicado 2017

Predictive classifier models built from natural products with antimalarial bioactivity using machine learning approach

por Egieyeh, Samuel, Syce, James, Malan, Sarel F., Christoffels, Alan
Publicado 2018

Exploration of Scaffolds from Natural Products with Antiplasmodial Activities, Currently Registered Antimalarial Drugs and Public Malarial Screen Data

por Egieyeh, Samuel, Syce, James, Christoffels, Alan, Malan, Sarel F.
Publicado 2016

Prioritization of anti-malarial hits from nature: chemo-informatic profiling of natural products with in vitro antiplasmodial activities and currently registered anti-malarial drug...

por Egieyeh, Samuel Ayodele, Syce, James, Malan, Sarel F., Christoffels, Alan
Publicado 2016

Computational drug repurposing strategy predicted peptide-based drugs that can potentially inhibit the interaction of SARS-CoV-2 spike protein with its target (humanACE2)

por Egieyeh, Samuel, Egieyeh, Elizabeth, Malan, Sarel, Christofells, Alan, Fielding, Burtram
Publicado 2021

Molecular modelling and simulation studies of the Mycobacterium tuberculosis multidrug efflux pump protein Rv1258c

por Cloete, Ruben, Kapp, Erika, Joubert, Jacques, Christoffels, Alan, Malan, Sarel F.
Publicado 2018

4-Oxatricyclo[5.2.1.0(2,6)]dec-8-ene-3,5-dione Derivatives as NMDA Receptor- and VGCC Blockers with Neuroprotective Potential

por Egunlusi, Ayodeji O., Malan, Sarel F., Omoruyi, Sylvester I., Ekpo, Okobi E., Joubert, Jacques
Publicado 2020

Design, synthesis, and evaluation of 3,7-substituted coumarin derivatives as multifunctional Alzheimer’s disease agents

por Mzezewa, Sheunopa C., Omoruyi, Sylvester I., Zondagh, Luke S., Malan, Sarel F., Ekpo, Okobi E., Joubert, Jacques
Publicado 2021

Antimycobacterial Activity, Synergism, and Mechanism of Action Evaluation of Novel Polycyclic Amines against Mycobacterium tuberculosis

por Kapp, Erika, Joubert, Jacques, Sampson, Samantha L., Warner, Digby F., Seldon, Ronnett, Jordaan, Audrey, de Vos, Margaretha, Sharma, Rajan, Malan, Sarel F.
Publicado 2021

International nonproprietary names for monoclonal antibodies: an evolving nomenclature system

por Guimaraes Koch, Sofia S., Thorpe, Robin, Kawasaki, Nana, Lefranc, Marie-Paule, Malan, Sarel, Martin, Andrew C.R., Mignot, Gilles, Plückthun, Andreas, Rizzi, Menico, Shubat, Stephanie, Weisser, Karin, Balocco, Raffaella
Publicado 2022

Versatility of 7-Substituted Coumarin Molecules as Antimycobacterial Agents, Neuronal Enzyme Inhibitors and Neuroprotective Agents

por Kapp, Erika, Visser, Hanri, Sampson, Samantha L., Malan, Sarel F., Streicher, Elizabeth M., Foka, Germaine B., Warner, Digby F., Omoruyi, Sylvester I., Enogieru, Adaze B., Ekpo, Okobi E., Zindo, Frank T., Joubert, Jacques
Publicado 2017