MICROFILAMENTS IN EPIDERMAL CANCER CELLS

por Malech, Harry L., Lentz, Thomas L.
Publicado 1974

Infectious Disease Rounds at Yale: Introduction to the Series

por Bia, Frank J., Malech, Harry L.
Publicado 1982

A Novel Method for Screening Adenosine Receptor Specific Agonists for Use in Adenosine Drug Development

por Jones, Karlie R., Choi, Uimook, Gao, Ji-Liang, Thompson, Robert D., Rodman, Larry E., Malech, Harry L., Kang, Elizabeth M.
Publicado 2017

Pyocyanin-Enhanced Neutrophil Extracellular Trap Formation Requires the NADPH Oxidase

por Rada, Balázs, Jendrysik, Meghan A., Pang, Lan, Hayes, Craig P., Yoo, Dae-goon, Park, Jonathan J., Moskowitz, Samuel M., Malech, Harry L., Leto, Thomas L.
Publicado 2013

Homozygous variant p. Arg90His in NCF1 is associated with early-onset Interferonopathy: a case report

por Schnappauf, Oskar, Heale, Liane, Dissanayake, Dilan, Tsai, Wanxia L., Gadina, Massimo, Leto, Thomas L., Kastner, Daniel L., Malech, Harry L., Kuhns, Douglas B., Aksentijevich, Ivona, Laxer, Ronald M.
Publicado 2021

Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease

por Lood, Christian, Blanco, Luz P., Purmalek, Monica M., Carmona-Rivera, Carmelo, De Ravin, Suk S., Smith, Carolyne K., Malech, Harry L., Ledbetter, Jeffrey A., Elkon, Keith B., Kaplan, Mariana J.
Publicado 2016

Interleukin-27 Enhances the Potential of Reactive Oxygen Species Generation from Monocyte-derived Macrophages and Dendritic cells by Induction of p47(phox)

por Sowrirajan, Bharatwaj, Saito, Yoshiro, Poudyal, Deepak, Chen, Qian, Sui, Hongyan, DeRavin, Suk See, Imamichi, Hiromi, Sato, Toyotaka, Kuhns, Douglas B., Noguchi, Noriko, Malech, Harry L., Lane, H. Clifford, Imamichi, Tomozumi
Publicado 2017

Granulibacter bethesdensis, a Pathogen from Patients with Chronic Granulomatous Disease, Produces a Penta-Acylated Hypostimulatory Glycero-D-talo-oct-2-ulosonic Acid–Lipid A Glycol...

por Muszyński, Artur, Zarember, Kol A., Heiss, Christian, Shiloach, Joseph, Berg, Lars J., Audley, John, Kozyr, Arina, Greenberg, David E., Holland, Steven M., Malech, Harry L., Azadi, Parastoo, Carlson, Russell W., Gallin, John I.
Publicado 2021

AMD3100 is a potent antagonist at CXCR4(R334X), a hyperfunctional mutant chemokine receptor and cause of WHIM syndrome

por McDermott, David H, Lopez, Joseph, Deng, Francis, Liu, Qian, Ojode, Teresa, Chen, Haoqian, Ulrick, Jean, Kwatemaa, Nana, Kelly, Corin, Anaya-O’Brien, Sandra, Garofalo, Mary, Marquesen, Martha, Hilligoss, Dianne, DeCastro, Rosamma, Malech, Harry L, Murphy, Philip M
Publicado 2011

Differentiation of human and murine induced pluripotent stem cells to microglia-like cells

por Pandya, Hetal, Shen, Michael J., Ichikawa, David M., Sedlock, Andrea B., Choi, Yong, Johnson, Kory R., Kim, Gloria, Brown, Mason A., Elkhaloun, Abdel G., Maric, Dragan, Sweeney, Colin L., Gossa, Selamawit, Malech, Harry L., McGavern, Dorian B., Park, John K.
Publicado 2017

Homozygous IL37 mutation associated with infantile inflammatory bowel disease

por Zhang, Zinan Z., Zhang, Yu, He, Tingyan, Sweeney, Colin L., Baris, Safa, Karakoc-Aydiner, Elif, Yao, Yikun, Ertem, Deniz, Matthews, Helen F., Gonzaga-Jauregui, Claudia, Malech, Harry L., Su, Helen C., Ozen, Ahmet, Smith, Kenneth G. C., Lenardo, Michael J.
Publicado 2021

Correction of X-CGD patient HSPCs by targeted CYBB cDNA insertion using CRISPR/Cas9 with 53BP1 inhibition for enhanced homology-directed repair

por Sweeney, Colin L., Pavel-Dinu, Mara, Choi, Uimook, Brault, Julie, Liu, Taylor, Koontz, Sherry, Li, Linhong, Theobald, Narda, Lee, Janet, Bello, Ezekiel A., Wu, Xiaolin, Meis, Ronald J., Dahl, Gary A., Porteus, Matthew H., Malech, Harry L., See De Ravin, Suk
Publicado 2021

Preclinical Optimization and Safety Studies of a New Lentiviral Gene Therapy for p47(phox)-Deficient Chronic Granulomatous Disease

por Schejtman, Andrea, Vetharoy, Winston, Choi, Uimook, Rivat, Christine, Theobald, Narda, Piras, Giuseppa, Leon-Rico, Diego, Buckland, Karen, Armenteros-Monterroso, Elena, Benedetti, Sara, Ashworth, Michael T., Rothe, Michael, Schambach, Axel, Gaspar, Hubert Bobby, Kang, Elizabeth M., Malech, Harry L., Thrasher, Adrian J., Santilli, Giorgia
Publicado 2021

Recurrent Granulibacter bethesdensis Infections and Chronic Granulomatous Disease

por Greenberg, David E., Shoffner, Adam R., Zelazny, Adrian M., Fenster, Michael E., Zarember, Kol A., Stock, Frida, Ding, Li, Marshall-Batty, Kimberly R., Wasserman, Richard L., Welch, David F., Kanakabandi, Kishore, Sturdevant, Dan E., Virtaneva, Kimmo, Porcella, Stephen F., Murray, Patrick R., Malech, Harry L., Holland, Steven M.
Publicado 2010

Preclinical evaluation for engraftment of CD34(+) cells gene-edited at the sickle cell disease locus in xenograft mouse and non-human primate models

por Uchida, Naoya, Li, Linhong, Nassehi, Tina, Drysdale, Claire M., Yapundich, Morgan, Gamer, Jackson, Haro-Mora, Juan J., Demirci, Selami, Leonard, Alexis, Bonifacino, Aylin C., Krouse, Allen E., Linde, N. Seth, Allen, Cornell, Peshwa, Madhusudan V., De Ravin, Suk See, Donahue, Robert E., Malech, Harry L., Tisdale, John F.
Publicado 2021

CRISPR-Cas9-AAV versus lentivector transduction for genome modification of X-linked severe combined immunodeficiency hematopoietic stem cells

por Brault, Julie, Liu, Taylor, Liu, Siyuan, Lawson, Amanda, Choi, Uimook, Kozhushko, Nikita, Bzhilyanskaya, Vera, Pavel-Dinu, Mara, Meis, Ronald J., Eckhaus, Michael A., Burkett, Sandra S., Bosticardo, Marita, Kleinstiver, Benjamin P., Notarangelo, Luigi D., Lazzarotto, Cicera R., Tsai, Shengdar Q., Wu, Xiaolin, Dahl, Gary A., Porteus, Matthew H., Malech, Harry L., De Ravin, Suk See
Publicado 2023

A phase III randomized crossover trial of plerixafor versus G-CSF for treatment of WHIM syndrome

por McDermott, David H., Velez, Daniel, Cho, Elena, Cowen, Edward W., DiGiovanna, John J., Pastrana, Diana V., Buck, Christopher B., Calvo, Katherine R., Gardner, Pamela J., Rosenzweig, Sergio D., Stratton, Pamela, Merideth, Melissa A., Kim, H. Jeffrey, Brewer, Carmen, Katz, James D., Kuhns, Douglas B., Malech, Harry L., Follmann, Dean, Fay, Michael P., Murphy, Philip M.
Publicado 2023

Targeted Gene Addition to a Safe Harbor locus in human CD34(+) Hematopoietic Stem Cells for Correction of X-linked Chronic Granulomatous Disease

por De Ravin, Suk See, Reik, Andreas, Liu, Pei-Qi, Li, Linhong, Wu, Xiaolin, Su, Ling, Raley, Castle, Theobald, Narda, Choi, Uimook, Song, Alexander H., Chan, Andy, Pearl, Jocelynn R., Paschon, David E., Lee, Janet, Newcombe, Hannah, Koontz, Sherry, Sweeney, Colin, Shivak, David A., Zarember, Kol A., Peshwa, Madhusudan V., Gregory, Philip D., Urnov, Fyodor D., Malech, Harry L.
Publicado 2016

Lentivector cryptic splicing mediates increase in CD34+ clones expressing truncated HMGA2 in human X-linked severe combined immunodeficiency

por De Ravin, Suk See, Liu, Siyuan, Sweeney, Colin L., Brault, Julie, Whiting-Theobald, Narda, Ma, Michelle, Liu, Taylor, Choi, Uimook, Lee, Janet, O’Brien, Sandra Anaya, Quackenbush, Priscilla, Estwick, Tyra, Karra, Anita, Docking, Ethan, Kwatemaa, Nana, Guo, Shuang, Su, Ling, Sun, Zhonghe, Zhou, Sheng, Puck, Jennifer, Cowan, Morton J., Notarangelo, Luigi D., Kang, Elizabeth, Malech, Harry L., Wu, Xiaolin
Publicado 2022

Self-organized yolk sac-like organoids allow for scalable generation of multipotent hematopoietic progenitor cells from induced pluripotent stem cells

por Tamaoki, Naritaka, Siebert, Stefan, Maeda, Takuya, Ha, Ngoc-Han, Good, Meghan L., Huang, Yin, Vodnala, Suman K., Haro-Mora, Juan J., Uchida, Naoya, Tisdale, John F., Sweeney, Colin L., Choi, Uimook, Brault, Julie, Koontz, Sherry, Malech, Harry L., Yamazaki, Yasuhiro, Isonaka, Risa, Goldstein, David S., Kimura, Masaki, Takebe, Takanori, Zou, Jizhong, Stroncek, David F., Robey, Pamela G., Kruhlak, Michael J., Restifo, Nicholas P., Vizcardo, Raul
Publicado 2023