Therapeutic Targeting of DNA Replication Stress in Cancer

por Gu, Long, Hickey, Robert J., Malkas, Linda H.
Publicado 2023

Clinical Significance of Serum Biomarkers in Pediatric Solid Mediastinal and Abdominal Tumors

por Sandoval, John A., Malkas, Linda H., Hickey, Robert J.
Publicado 2012

Partial Purification of a Megadalton DNA Replication Complex by Free Flow Electrophoresis

por Li, Caroline M., Miao, Yunan, Lingeman, Robert G., Hickey, Robert J., Malkas, Linda H.
Publicado 2016

Dissecting the PI3K Signaling Axis in Pediatric Solid Tumors: Novel Targets for Clinical Integration

por Loh, Amos H. P., Brennan, Rachel C., Lang, Walter H., Hickey, Robert J., Malkas, Linda H., Sandoval, John A.
Publicado 2013

Molecular Targeting of Cancer-Associated PCNA Interactions in Pancreatic Ductal Adenocarcinoma Using a Cell-Penetrating Peptide

por Smith, Shanna J., Li, Caroline M., Lingeman, Robert G., Hickey, Robert J., Liu, Yilun, Malkas, Linda H., Raoof, Mustafa
Publicado 2020

Novel Peptide Therapeutic Approaches for Cancer Treatment

por Li, Caroline M., Haratipour, Pouya, Lingeman, Robert G., Perry, J. Jefferson P., Gu, Long, Hickey, Robert J., Malkas, Linda H.
Publicado 2021

A Novel Berbamine Derivative Inhibits Cell Viability and Induces Apoptosis in Cancer Stem-Like Cells of Human Glioblastoma, via Up-Regulation of miRNA-4284 and JNK/AP-1 Signaling

por Yang, Fan, Nam, Sangkil, Brown, Christine E., Zhao, Robin, Starr, Renate, Horne, David A., Malkas, Linda H., Jove, Richard, Hickey, Robert J.
Publicado 2014

A PCNA-Derived Cell Permeable Peptide Selectively Inhibits Neuroblastoma Cell Growth

por Gu, Long, Smith, Shanna, Li, Caroline, Hickey, Robert J., Stark, Jeremy M., Fields, Gregg B., Lang, Walter H., Sandoval, John A., Malkas, Linda H.
Publicado 2014

The Mechanism by Which MYCN Amplification Confers an Enhanced Sensitivity to a PCNA-Derived Cell Permeable Peptide in Neuroblastoma Cells

por Gu, Long, Chu, Peiguo, Lingeman, Robert, McDaniel, Heather, Kechichian, Steven, Hickey, Robert J., Liu, Zheng, Yuan, Yate-Ching, Sandoval, John A., Fields, Gregg B., Malkas, Linda H.
Publicado 2015

Arginine shortage induces replication stress and confers genotoxic resistance by inhibiting histone H4 translation and promoting PCNA polyubiquitination

por Wang, Yi-Chang, Kelso, Andrew A., Karamafrooz, Adak, Chen, Yi-Hsuan, Chen, Wei-Kai, Cheng, Chun-Ting, Qi, Yue, Gu, Long, Malkas, Linda, Kung, Hsing-Jien, Moldovan, George-Lucian, Ciccia, Alberto, Stark, Jeremy M., Ann, David K
Publicado 2023

Arginine shortage induces replication stress and confers genotoxic resistance by inhibiting histone H4 translation and promoting PCNA ubiquitination

por Wang, Yi-Chang, Kelso, Andrew A., Karamafrooz, Adak, Chen, Yi-Hsuan, Chen, Wei-Kai, Cheng, Chun-Ting, Qi, Yue, Gu, Long, Malkas, Linda, Taglialatela, Angelo, Kung, Hsing-Jien, Moldovan, George-Lucian, Ciccia, Alberto, Stark, Jeremy M., Ann, David K.
Publicado 2023

Small molecule targeting of transcription-replication conflict for selective chemotherapy

por Gu, Long, Li, Min, Li, Caroline M., Haratipour, Pouya, Lingeman, Robert, Jossart, Jennifer, Gutova, Margarita, Flores, Linda, Hyde, Caitlyn, Kenjić, Nikola, Li, Haiqing, Chung, Vincent, Li, Hongzhi, Lomenick, Brett, Von Hoff, Daniel D., Synold, Timothy W., Aboody, Karen S., Liu, Yilun, Horne, David, Hickey, Robert J., Perry, J. Jefferson P., Malkas, Linda H.
Publicado 2023

Comparison of RNA-seq and microarray-based models for clinical endpoint prediction

por Zhang, Wenqian, Yu, Ying, Hertwig, Falk, Thierry-Mieg, Jean, Zhang, Wenwei, Thierry-Mieg, Danielle, Wang, Jian, Furlanello, Cesare, Devanarayan, Viswanath, Cheng, Jie, Deng, Youping, Hero, Barbara, Hong, Huixiao, Jia, Meiwen, Li, Li, Lin, Simon M, Nikolsky, Yuri, Oberthuer, André, Qing, Tao, Su, Zhenqiang, Volland, Ruth, Wang, Charles, Wang, May D., Ai, Junmei, Albanese, Davide, Asgharzadeh, Shahab, Avigad, Smadar, Bao, Wenjun, Bessarabova, Marina, Brilliant, Murray H., Brors, Benedikt, Chierici, Marco, Chu, Tzu-Ming, Zhang, Jibin, Grundy, Richard G., He, Min Max, Hebbring, Scott, Kaufman, Howard L., Lababidi, Samir, Lancashire, Lee J., Li, Yan, Lu, Xin X., Luo, Heng, Ma, Xiwen, Ning, Baitang, Noguera, Rosa, Peifer, Martin, Phan, John H., Roels, Frederik, Rosswog, Carolina, Shao, Susan, Shen, Jie, Theissen, Jessica, Tonini, Gian Paolo, Vandesompele, Jo, Wu, Po-Yen, Xiao, Wenzhong, Xu, Joshua, Xu, Weihong, Xuan, Jiekun, Yang, Yong, Ye, Zhan, Dong, Zirui, Zhang, Ke K., Yin, Ye, Zhao, Chen, Zheng, Yuanting, Wolfinger, Russell D., Shi, Tieliu, Malkas, Linda H., Berthold, Frank, Wang, Jun, Tong, Weida, Shi, Leming, Peng, Zhiyu, Fischer, Matthias
Publicado 2015