Biophysical Correlates of Enhanced Immunogenicity of a Stabilized Variant of the Receptor Binding Domain of SARS-CoV-2

por Kanjo, Kawkab, Chattopadhyay, Gopinath, Malladi, Sameer Kumar, Singh, Randhir, Jayatheertha, Sowrabha, Varadarajan, Raghavan
Publicado 2023

One-step sequence and structure-guided optimization of HIV-1 envelope gp140

por Malladi, Sameer Kumar, Schreiber, David, Pramanick, Ishika, Sridevi, Malavika Abhineshababu, Goldenzweig, Adi, Dutta, Somnath, Fleishman, Sarel Jacob, Varadarajan, Raghavan
Publicado 2020

Protective Efficacy of Recombinant Influenza Hemagglutinin Ectodomain Fusions

por Mittal, Nidhi, Sengupta, Nayanika, Malladi, Sameer Kumar, Reddy, Poorvi, Bhat, Madhuraj, Rajmani, Raju S., Sedeyn, Koen, Saelens, Xavier, Dutta, Somnath, Varadarajan, Raghavan
Publicado 2021

A dimeric proteomimetic prevents SARS-CoV-2 infection by dimerizing the spike protein

por Khatri, Bhavesh, Pramanick, Ishika, Malladi, Sameer Kumar, Rajmani, Raju S., Kumar, Sahil, Ghosh, Pritha, Sengupta, Nayanika, Rahisuddin, R., Kumar, Narender, Kumaran, S., Ringe, Rajesh P., Varadarajan, Raghavan, Dutta, Somnath, Chatterjee, Jayanta
Publicado 2022

Design of a highly thermotolerant, immunogenic SARS-CoV-2 spike fragment

por Malladi, Sameer Kumar, Singh, Randhir, Pandey, Suman, Gayathri, Savitha, Kanjo, Kawkab, Ahmed, Shahbaz, Khan, Mohammad Suhail, Kalita, Parismita, Girish, Nidhi, Upadhyaya, Aditya, Reddy, Poorvi, Pramanick, Ishika, Bhasin, Munmun, Mani, Shailendra, Bhattacharyya, Sankar, Joseph, Jeswin, Thankamani, Karthika, Raj, V. Stalin, Dutta, Somnath, Singh, Ramandeep, Nadig, Gautham, Varadarajan, Raghavan
Publicado 2020

Highly Thermotolerant SARS-CoV-2 Vaccine Elicits Neutralising Antibodies against Delta and Omicron in Mice

por Jansen van Vuren, Petrus, McAuley, Alexander J., Kuiper, Michael J., Singanallur, Nagendrakumar Balasubramanian, Bruce, Matthew P., Riddell, Shane, Goldie, Sarah, Mangalaganesh, Shruthi, Chahal, Simran, Drew, Trevor W., Blasdell, Kim R., Tachedjian, Mary, Caly, Leon, Druce, Julian D., Ahmed, Shahbaz, Khan, Mohammad Suhail, Malladi, Sameer Kumar, Singh, Randhir, Pandey, Suman, Varadarajan, Raghavan, Vasan, Seshadri S.
Publicado 2022

A Stabilized, Monomeric, Receptor Binding Domain Elicits High-Titer Neutralizing Antibodies Against All SARS-CoV-2 Variants of Concern

por Ahmed, Shahbaz, Khan, Mohammad Suhail, Gayathri, Savitha, Singh, Randhir, Kumar, Sahil, Patel, Unnatiben Rajeshbhai, Malladi, Sameer Kumar, Rajmani, Raju S., van Vuren, Petrus Jansen, Riddell, Shane, Goldie, Sarah, Girish, Nidhi, Reddy, Poorvi, Upadhyaya, Aditya, Pandey, Suman, Siddiqui, Samreen, Tyagi, Akansha, Jha, Sujeet, Pandey, Rajesh, Khatun, Oyahida, Narayan, Rohan, Tripathi, Shashank, McAuley, Alexander J., Singanallur, Nagendrakumar Balasubramanian, Vasan, Seshadri S., Ringe, Rajesh P., Varadarajan, Raghavan
Publicado 2021

Immunogenicity and Protective Efficacy of a Highly Thermotolerant, Trimeric SARS-CoV-2 Receptor Binding Domain Derivative

por Malladi, Sameer Kumar, Patel, Unnatiben Rajeshbhai, Rajmani, Raju S., Singh, Randhir, Pandey, Suman, Kumar, Sahil, Khaleeq, Sara, van Vuren, Petrus Jansen, Riddell, Shane, Goldie, Sarah, Gayathri, Savitha, Chakraborty, Debajyoti, Kalita, Parismita, Pramanick, Ishika, Agarwal, Nupur, Reddy, Poorvi, Girish, Nidhi, Upadhyaya, Aditya, Khan, Mohammad Suhail, Kanjo, Kawkab, Bhat, Madhuraj, Mani, Shailendra, Bhattacharyya, Sankar, Siddiqui, Samreen, Tyagi, Akansha, Jha, Sujeet, Pandey, Rajesh, Tripathi, Shashank, Dutta, Somnath, McAuley, Alexander J., Singanallur, Nagendrakumar Balasubramanian, Vasan, Seshadri S., Ringe, Rajesh P., Varadarajan, Raghavan
Publicado 2021