The Rise of FXR1: Escaping Cellular Senescence in Head and Neck Squamous Cell Carcinoma

por Fernández, Erlinda, Mallette, Frédérick A.
Publicado 2016

SOCS1, a novel interaction partner of p53 controlling oncogene-induced senescence

por Mallette, Frédérick A., Calabrese, Viviane, Ilangumaran, Subburaj, Ferbeyre, Gerardo
Publicado 2010

MyD88 Regulates the Expression of SMAD4 and the Iron Regulatory Hormone Hepcidin

por Samba-Mondonga, Macha, Calvé, Annie, Mallette, Frédérick A., Santos, Manuela M.
Publicado 2018

Ablation of PRMT6 reveals a role as a negative transcriptional regulator of the p53 tumor suppressor

por Neault, Mathieu, Mallette, Frédérick A., Vogel, Gillian, Michaud-Levesque, Jonathan, Richard, Stéphane
Publicado 2012

Urodele p53 tolerates amino acid changes found in p53 variants linked to human cancer

por Villiard, Éric, Brinkmann, Henner, Moiseeva, Olga, Mallette, Frédérick A, Ferbeyre, Gerardo, Roy, Stéphane
Publicado 2007

mTOR as a central regulator of lifespan and aging

por Papadopoli, David, Boulay, Karine, Kazak, Lawrence, Pollak, Michael, Mallette, Frédérick A., Topisirovic, Ivan, Hulea, Laura
Publicado 2019

Tyrosine phosphorylation of DEPTOR functions as a molecular switch to activate mTOR signaling

por M. Gagné, Laurence, Morin, Nadine, Lavoie, Noémie, Bisson, Nicolas, Lambert, Jean-Philippe, Mallette, Frédérick A., Huot, Marc-Étienne
Publicado 2021

ZNF768: controlling cellular senescence and proliferation with ten fingers

por Villot, Romain, Poirier, Audrey, Devillers, Romain, Kolnoguz, Aliona, Elowe, Sabine, Manem, Venkata S. K., Joubert, Philippe, Mallette, Frédérick A., Laplante, Mathieu
Publicado 2021

Obesity triggers tumoral senescence and renders poorly immunogenic malignancies amenable to senolysis

por Fournier, Frédérik, Diaz-Marin, Roberto, Pilon, Frédérique, Neault, Mathieu, Juneau, Rachel, Girouard, Gabrielle, Wilson, Ariel M., Larrivée, Bruno, Mallette, Frédérick A., Crespo-Garcia, Sergio, Sapieha, Przemyslaw
Publicado 2022

An inventory of crosstalk between ubiquitination and other post-translational modifications in orchestrating cellular processes

por Barbour, Haithem, Nkwe, Nadine Sen, Estavoyer, Benjamin, Messmer, Clémence, Gushul-Leclaire, Mila, Villot, Romain, Uriarte, Maxime, Boulay, Karine, Hlayhel, Sari, Farhat, Bassel, Milot, Eric, Mallette, Frédérick A., Daou, Salima, Affar, El Bachir
Publicado 2023

p16(INK4a) Regulates Cellular Senescence in PD-1-Expressing Human T Cells

por Janelle, Valérie, Neault, Mathieu, Lebel, Marie-Ève, De Sousa, Dave Maurice, Boulet, Salix, Durrieu, Ludovic, Carli, Cédric, Muzac, Chloé, Lemieux, Sébastien, Labrecque, Nathalie, Melichar, Heather J., Mallette, Frédérick A., Delisle, Jean-Sébastien
Publicado 2021

HIF1α-dependent hypoxia response in myeloid cells requires IRE1α

por Mawambo, Gaëlle, Oubaha, Malika, Ichiyama, Yusuke, Blot, Guillaume, Crespo-Garcia, Sergio, Dejda, Agnieszka, Binet, François, Diaz-Marin, Roberto, Sawchyn, Christina, Sergeev, Mikhail, Juneau, Rachel, Kaufman, Randal J., Affar, El Bachir, Mallette, Frédérick A., Wilson, Ariel M., Sapieha, Przemyslaw
Publicado 2023

A genome-wide screen identifies SCAI as a modulator of the UV-induced replicative stress response

por Lemay, Jean-François, St-Hilaire, Edlie, Ronato, Daryl A., Gao, Yuandi, Bélanger, François, Gezzar-Dandashi, Sari, Kimenyi Ishimwe, Aimé Boris, Sawchyn, Christina, Lévesque, Dominique, McQuaid, Mary, Boisvert, François-Michel, Mallette, Frédérick A., Masson, Jean-Yves, Drobetsky, Elliot A., Wurtele, Hugo
Publicado 2022

The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway

por Carbonneau, Mélissa, M. Gagné, Laurence, Lalonde, Marie-Eve, Germain, Marie-Anne, Motorina, Alena, Guiot, Marie-Christine, Secco, Blandine, Vincent, Emma E., Tumber, Anthony, Hulea, Laura, Bergeman, Jonathan, Oppermann, Udo, Jones, Russell G., Laplante, Mathieu, Topisirovic, Ivan, Petrecca, Kevin, Huot, Marc-Étienne, Mallette, Frédérick A.
Publicado 2016

FIRRM cooperates with FIGNL1 to promote RAD51 disassembly during DNA repair

por Pinedo-Carpio, Edgar, Dessapt, Julien, Beneyton, Adèle, Sacre, Lauralicia, Bérubé, Marie-Anne, Villot, Romain, Lavoie, Elise G., Coulombe, Yan, Blondeau, Andréanne, Boulais, Jonathan, Malina, Abba, Luo, Vincent M., Lazaratos, Anna-Maria, Côté, Jean-François, Mallette, Frédérick A., Guarné, Alba, Masson, Jean-Yves, Fradet-Turcotte, Amélie, Orthwein, Alexandre
Publicado 2023

ZNF768 links oncogenic RAS to cellular senescence

por Villot, Romain, Poirier, Audrey, Bakan, Inan, Boulay, Karine, Fernández, Erlinda, Devillers, Romain, Gama-Braga, Luciano, Tribouillard, Laura, Gagné, Andréanne, Duchesne, Éma, Caron, Danielle, Bérubé, Jean-Sébastien, Bérubé, Jean-Christophe, Coulombe, Yan, Orain, Michèle, Gélinas, Yves, Gobeil, Stéphane, Bossé, Yohan, Masson, Jean-Yves, Elowe, Sabine, Bilodeau, Steve, Manem, Venkata, Joubert, Philippe, Mallette, Frédérick A., Laplante, Mathieu
Publicado 2021

Starvation-induced proteasome assemblies in the nucleus link amino acid supply to apoptosis

por Uriarte, Maxime, Sen Nkwe, Nadine, Tremblay, Roch, Ahmed, Oumaima, Messmer, Clémence, Mashtalir, Nazar, Barbour, Haithem, Masclef, Louis, Voide, Marion, Viallard, Claire, Daou, Salima, Abdelhadi, Djaileb, Ronato, Daryl, Paydar, Mohammadjavad, Darracq, Anaïs, Boulay, Karine, Desjardins-Lecavalier, Nicolas, Sapieha, Przemyslaw, Masson, Jean-Yves, Sergeev, Mikhail, Kwok, Benjamin H., Hulea, Laura, Mallette, Frédérick A., Milot, Eric, Larrivée, Bruno, Wurtele, Hugo, Affar, El Bachir
Publicado 2021