Extracellular SPARC cooperates with TGF-β signalling to induce pro-fibrotic activation of systemic sclerosis patient dermal fibroblasts

por Carvalheiro, Tiago, Malvar Fernández, Beatriz, Ottria, Andrea, Giovannone, Barbara, Marut, Wioleta, Reedquist, Kris A, Garcia, Samuel, Radstake, Timothy R
Publicado 2020

Semaphorin4A-Plexin D1 Axis Induces Th2 and Th17 While Represses Th1 Skewing in an Autocrine Manner

por Carvalheiro, Tiago, Rafael-Vidal, Carlos, Malvar-Fernandez, Beatriz, Lopes, Ana P., Pego-Reigosa, Jose M., Radstake, Timothy R. D. J., Garcia, Samuel
Publicado 2020

Distinctive CD26 Expression on CD4 T-Cell Subsets

por Cordero, Oscar J., Rafael-Vidal, Carlos, Varela-Calviño, Rubén, Calviño-Sampedro, Cristina, Malvar-Fernández, Beatriz, García, Samuel, Viñuela, Juan E., Pego-Reigosa, José M.
Publicado 2021

Induction of Inflammation and Fibrosis by Semaphorin 4A in Systemic Sclerosis

por Carvalheiro, Tiago, Affandi, Alsya J., Malvar‐Fernández, Beatriz, Dullemond, Ilse, Cossu, Marta, Ottria, Andrea, Mertens, Jorre S., Giovannone, Barbara, Bonte‐Mineur, Femke, Kok, Marc R., Marut, Wioleta, Reedquist, Kris A., Radstake, Timothy R., García, Samuel
Publicado 2019

HOXA5 is a key regulator of class 3 semaphorins expression in the synovium of rheumatoid arthritis patients

por Martínez-Ramos, Sara, Rafael-Vidal, Carlos, Malvar-Fernández, Beatriz, Rodriguez-Trillo, Angela, Veale, Douglas, Fearon, Ursula, Conde, Carmen, Conde-Aranda, Javier, Radstake, Timothy R D J, Pego-Reigosa, Jose María, Reedquist, Kris A, García, Samuel
Publicado 2022

Histone deacetylase 3 regulates the inflammatory gene expression programme of rheumatoid arthritis fibroblast-like synoviocytes

por Angiolilli, Chiara, Kabala, Pawel A, Grabiec, Aleksander M, Van Baarsen, Iris M, Ferguson, Bradley S, García, Samuel, Malvar Fernandez, Beatriz, McKinsey, Timothy A, Tak, Paul P, Fossati, Gianluca, Mascagni, Paolo, Baeten, Dominique L, Reedquist, Kris A
Publicado 2017

Promotion of macrophage activation by Tie2 in the context of the inflamed synovia of rheumatoid arthritis and psoriatic arthritis patients

por Kabala, Pawel A, Malvar-Fernández, Beatriz, Lopes, Ana P, Carvalheiro, Tiago, Hartgring, Sarita A Y, Tang, Man Wai, Conde, Carmen, Baeten, Dominique L, Sleeman, Matthew, Tak, Paul P, Connor, Jane, Radstake, Timothy R, Reedquist, Kris A, García, Samuel
Publicado 2020

Angiopoietin-2 Promotes Inflammatory Activation in Monocytes of Systemic Sclerosis Patients

por Carvalheiro, Tiago, Lopes, Ana P., van der Kroef, Maarten, Malvar-Fernandez, Beatriz, Rafael-Vidal, Carlos, Hinrichs, Anneline C., Servaas, Nila H., Bonte-Mineur, Femke, Kok, Marc R., Beretta, Lorenzo, Zimmermann, Maili, Marut, Wioleta, Pego-Reigosa, Jose M., Radstake, Timothy R. D. J., Garcia, Samuel
Publicado 2020

Central Role of Semaphorin 3B in a Serum‐Induced Arthritis Model and Reduced Levels in Patients With Rheumatoid Arthritis

por Igea, Ana, Carvalheiro, Tiago, Malvar‐Fernández, Beatriz, Martinez‐Ramos, Sara, Rafael‐Vidal, Carlos, Niemantsverdriet, Ellis, Varadé, Jezabel, Fernández‐Carrera, Andrea, Jimenez, Norman, McGarry, Trudy, Rodriguez‐Trillo, Angela, Veale, Douglas, Fearon, Ursula, Conde, Carmen, Pego‐Reigosa, Jose M., González‐Fernández, África, Reedquist, Kris A., Radstake, Timothy R. D. J., van der Helm‐Van Mil, Annette, García, Samuel
Publicado 2022