Targeting Autophagy Addiction in Cancer

por Mancias, Joseph D., Kimmelman, Alec C.
Publicado 2011

The Role of NCOA4-Mediated Ferritinophagy in Health and Disease

por Santana-Codina, Naiara, Mancias, Joseph D.
Publicado 2018

NCOA4-Mediated Ferritinophagy: A Potential Link to Neurodegeneration

por Quiles del Rey, Maria, Mancias, Joseph D.
Publicado 2019

Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy

por Mancias, Joseph D., Wang, Xiaoxu, Gygi, Steven P., Harper, J. Wade, Kimmelman, Alec C.
Publicado 2014

Autophagy supports mitochondrial metabolism through the regulation of iron homeostasis in pancreatic cancer

por Mukhopadhyay, Subhadip, Encarnación-Rosado, Joel, Lin, Elaine Y., Sohn, Albert S. W., Zhang, Huan, Mancias, Joseph D., Kimmelman, Alec C.
Publicado 2023

Stereotactic Body Radiotherapy (SBRT) Reirradiation for Recurrent Pancreas Cancer

por Dagoglu, Nergiz, Callery, Mark, Moser, James, Tseng, Jennifer, Kent, Tara, Bullock, Andrea, Miksad, Rebecca, Mancias, Joseph D., Mahadevan, Anand
Publicado 2016

Autophagy is required for proper cysteine homeostasis in pancreatic cancer through regulation of SLC7A11

por Mukhopadhyay, Subhadip, Biancur, Douglas E., Parker, Seth J., Yamamoto, Keisuke, Banh, Robert S., Paulo, Joao A., Mancias, Joseph D., Kimmelman, Alec C.
Publicado 2021

PTEN-induced kinase PINK1 supports colorectal cancer growth by regulating the labile iron pool

por Chen, Brandon, Das, Nupur K., Talukder, Indrani, Singhal, Rashi, Castillo, Cristina, Andren, Anthony, Mancias, Joseph D., Lyssiotis, Costas A., Shah, Yatrik M.
Publicado 2023

Stereotactic Body Radiotherapy (SBRT) for Intrahepatic and Hilar Cholangiocarcinoma

por Mahadevan, Anand, Dagoglu, Nergiz, Mancias, Joseph, Raven, Kristin, Khwaja, Khalid, Tseng, Jennifer F, Ng, Kimmie, Enzinger, Peter, Miksad, Rebecca, Bullock, Andrea, Evenson, Amy
Publicado 2015

Respiratory Supercomplexes Promote Mitochondrial Efficiency and Growth in Severely Hypoxic Pancreatic Cancer

por Hollinshead, Kate E.R., Parker, Seth J., Eapen, Vinay V., Encarnacion-Rosado, Joel, Sohn, Albert, Oncu, Tugba, Cammer, Michael, Mancias, Joseph D., Kimmelman, Alec C.
Publicado 2020

Ferritinophagy via NCOA4 is required for erythropoiesis and is regulated by iron dependent HERC2-mediated proteolysis

por Mancias, Joseph D, Pontano Vaites, Laura, Nissim, Sahar, Biancur, Douglas E, Kim, Andrew J, Wang, Xiaoxu, Liu, Yu, Goessling, Wolfram, Kimmelman, Alec C, Harper, J Wade
Publicado 2015

Proteomic and Transcriptomic Landscapes of Alström and Bardet–Biedl Syndromes

por Smyczynska, Urszula, Stanczak, Marcin, Kuljanin, Miljan, Włodarczyk, Aneta, Stoczynska-Fidelus, Ewelina, Taha, Joanna, Pawlik, Bartłomiej, Borowiec, Maciej, Mancias, Joseph D., Mlynarski, Wojciech, Rieske, Piotr, Fendler, Wojciech, Zmysłowska, Agnieszka
Publicado 2022

NCOA4 maintains murine erythropoiesis via cell autonomous and non-autonomous mechanisms

por Santana-Codina, Naiara, Gableske, Sebastian, del Rey, Maria Quiles, Małachowska, Beata, Jedrychowski, Mark P., Biancur, Douglas E., Schmidt, Paul J., Fleming, Mark D., Fendler, Wojciech, Harper, J. Wade, Kimmelman, Alec C., Mancias, Joseph D.
Publicado 2019

Rapid and direct control of target protein levels with VHL-recruiting dTAG molecules

por Nabet, Behnam, Ferguson, Fleur M., Seong, Bo Kyung A., Kuljanin, Miljan, Leggett, Alan L., Mohardt, Mikaela L., Robichaud, Amanda, Conway, Amy S., Buckley, Dennis L., Mancias, Joseph D., Bradner, James E., Stegmaier, Kimberly, Gray, Nathanael S.
Publicado 2020

Compensatory metabolic networks in pancreatic cancers upon perturbation of glutamine metabolism

por Biancur, Douglas E., Paulo, Joao A., Małachowska, Beata, Del Rey, Maria Quiles, Sousa, Cristovão M., Wang, Xiaoxu, Sohn, Albert S. W., Chu, Gerald C., Gygi, Steven P., Harper, J. Wade, Fendler, Wojciech, Mancias, Joseph D., Kimmelman, Alec C.
Publicado 2017

Plasticity in binding confers selectivity in ligand induced protein degradation

por Nowak, Radosław P., DeAngelo, Stephen L., Buckley, Dennis, He, Zhixiang, Donovan, Katherine A., An, Jian, Safaee, Nozhat, Jedrychowski, Mark P., Ponthier, Charles M., Ishoey, Mette, Zhang, Tinghu, Mancias, Joseph D., Gray, Nathanael S., Bradner, James E., Fischer, Eric S.
Publicado 2018

Multiomic analysis on human cell model of wolfram syndrome reveals changes in mitochondrial morphology and function

por Zmyslowska, Agnieszka, Kuljanin, Miljan, Malachowska, Beata, Stanczak, Marcin, Michalek, Dominika, Wlodarczyk, Aneta, Grot, Dagmara, Taha, Joanna, Pawlik, Bartłomiej, Lebiedzińska-Arciszewska, Magdalena, Nieznanska, Hanna, Wieckowski, Mariusz R., Rieske, Piotr, Mancias, Joseph D., Borowiec, Maciej, Mlynarski, Wojciech, Fendler, Wojciech
Publicado 2021

Comparison of MR‐soft tissue based versus biliary stent based alignment for image guidance in pancreatic SBRT

por Han, Zhaohui, Sudhyadhom, Atchar, Hsu, Shu‐Hui, Hu, Yue‐Houng, Mak, Raymond H., Huynh, Mai Anh, van Dams, Ritchell R., Tanguturi, Shyam, Venkatachalam, Veena, Mancias, Joseph D., Mamon, Harvey J., Martin, Neil E., Lam, Miranda B., Leeman, Jonathan E.
Publicado 2023

Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I

por Yamamoto, Keisuke, Venida, Anthony, Yano, Julian, Biancur, Douglas E., Kakiuchi, Miwako, Gupta, Suprit, Sohn, Albert S.W., Mukhopadhyay, Subhadip, Lin, Elaine Y., Parker, Seth J., Banh, Robert S., Paulo, Joao A., Wen, Kwun Wah, Debnath, Jayanta, Kim, Grace E., Mancias, Joseph D., Fearon, Douglas T., Perera, Rushika M., Kimmelman, Alec C.
Publicado 2020

An In Vivo CRISPR Screening Platform for Prioritizing Therapeutic Targets in AML

por Lin, Shan, Larrue, Clément, Scheidegger, Nastassja K., Seong, Bo Kyung A., Dharia, Neekesh V., Kuljanin, Miljan, Wechsler, Caroline S., Kugener, Guillaume, Robichaud, Amanda L., Conway, Amy Saur, Mashaka, Thelma, Mouche, Sarah, Adane, Biniam, Ryan, Jeremy A., Mancias, Joseph D., Younger, Scott T., Piccioni, Federica, Lee, Lynn H., Wunderlich, Mark, Letai, Anthony, Tamburini, Jérôme, Stegmaier, Kimberly
Publicado 2022