Androgen Receptor Functional Analyses by High Throughput Imaging: Determination of Ligand, Cell Cycle, and Mutation-Specific Effects

por Szafran, Adam T., Szwarc, Maria, Marcelli, Marco, Mancini, Michael A.
Publicado 2008

Sensitive image-based chromatin binding assays using inducible ERα to rapidly characterize estrogenic chemicals and mixtures

por Szafran, Adam T., Mancini, Maureen G., Stossi, Fabio, Mancini, Michael A.
Publicado 2022

Leveraging Image-Derived Phenotypic Measurements for Drug-Target Interaction Predictions

por Kuthuru, Srikanth, Szafran, Adam T, Stossi, Fabio, Mancini, Michael A, Rao, Arvind
Publicado 2019

Homeostatic levels of SRC-2 and SRC-3 promote early human adipogenesis

por Hartig, Sean M., He, Bin, Long, Weiwen, Buehrer, Benjamin M., Mancini, Michael A.
Publicado 2011

Characterizing properties of non-estrogenic substituted bisphenol analogs using high throughput microscopy and image analysis

por Szafran, Adam T., Stossi, Fabio, Mancini, Maureen G., Walker, Cheryl L., Mancini, Michael A.
Publicado 2017

Measuring Mobility in Chromatin by Intensity-Sorted FCS

por Di Bona, Melody, Mancini, Michael A., Mazza, Davide, Vicidomini, Giuseppe, Diaspro, Alberto, Lanzanò, Luca
Publicado 2019

Coactivators enable glucocorticoid receptor recruitment to fine-tune estrogen receptor transcriptional responses

por Bolt, Michael J., Stossi, Fabio, Newberg, Justin Y., Orjalo, Arturo, Johansson, Hans E., Mancini, Michael A.
Publicado 2013

Activation of Estrogen Receptor-α by E2 or EGF Induces Temporally Distinct Patterns of Large-Scale Chromatin Modification and mRNA Transcription

por Berno, Valeria, Amazit, Larbi, Hinojos, Cruz, Zhong, Jeannie, Mancini, Maureen G., Dave Sharp, Zelton, Mancini, Michael A.
Publicado 2008

Unraveling the regulatory connections between two controllers of breast cancer cell fate

por Lee, Jinho, Tiwari, Abhinav, Shum, Victor, Mills, Gordon B., Mancini, Michael A., Igoshin, Oleg A., Balázsi, Gábor
Publicado 2014

Tributyltin chloride (TBT) induces RXRA down-regulation and lipid accumulation in human liver cells

por Stossi, Fabio, Dandekar, Radhika D., Johnson, Hannah, Lavere, Philip, Foulds, Charles E., Mancini, Maureen G., Mancini, Michael A.
Publicado 2019

Identification of celastrol as a novel HIV-1 latency reversal agent by an image-based screen

por Liu, Hongbing, Hu, Pei-Wen, Dubrulle, Julien, Stossi, Fabio, Nikolai, Bryan C., Mancini, Michael A., Rice, Andrew P.
Publicado 2021

Endocrine disrupting chemicals differentially alter intranuclear dynamics and transcriptional activation of estrogen receptor-α

por Bolt, Michael J., Singh, Pankaj, Obkirchner, Caroline E., Powell, Reid T., Mancini, Maureen G., Szafran, Adam T., Stossi, Fabio, Mancini, Michael A.
Publicado 2021

High throughput microscopy identifies bisphenol AP, a bisphenol A analog, as a novel AR down-regulator

por Stossi, Fabio, Dandekar, Radhika D., Bolt, Michael J., Newberg, Justin Y., Mancini, Maureen G., Kaushik, Akash K., Putluri, Vasanta, Sreekumar, Arun, Mancini, Michael A.
Publicado 2016

Unique cellular protrusions mediate breast cancer cell migration by tethering to osteogenic cells

por Muscarella, Aaron M., Dai, Wei, Mitchell, Patrick G., Zhang, Weijie, Wang, Hai, Jia, Luyu, Stossi, Fabio, Mancini, Michael A., Chiu, Wah, Zhang, Xiang H.-F.
Publicado 2020

Therapeutically actionable signaling node to rescue AURKA driven loss of primary cilia in VHL-deficient cells

por Chowdhury, Pratim, Perera, Dimuthu, Powell, Reid T., Talley, Tia, Tripathi, Durga Nand, Park, Yong Sung, Mancini, Michael A., Davies, Peter, Stephan, Clifford, Coarfa, Cristian, Dere, Ruhee
Publicado 2021

Author Correction: Therapeutically actionable signaling node to rescue AURKA driven loss of primary cilia in VHL-deficient cells

por Chowdhury, Pratim, Perera, Dimuthu, Powell, Reid T., Talley, Tia, Tripathi, Durga Nand, Park, Yong Sung, Mancini, Michael A., Davies, Peter, Stephan, Clifford, Coarfa, Cristian, Dere, Ruhee
Publicado 2021

Quality Control for Single Cell Imaging Analytics Using Endocrine Disruptor-Induced Changes in Estrogen Receptor Expression

por Stossi, Fabio, Singh, Pankaj K., Mistry, Ragini M., Johnson, Hannah L., Dandekar, Radhika D., Mancini, Maureen G., Szafran, Adam T., Rao, Arvind U., Mancini, Michael A.
Publicado 2022

Bexarotene – a novel modulator of AURKA and the primary cilium in VHL-deficient cells

por Chowdhury, Pratim, Powell, Reid T., Stephan, Clifford, Uray, Ivan P., Talley, Tia, Karki, Menuka, Tripathi, Durga Nand, Park, Yong Sung, Mancini, Michael A., Davies, Peter, Dere, Ruhee
Publicado 2018

Classification of estrogenic compounds by coupling high content analysis and machine learning algorithms

por Mukherjee, Rajib, Beykal, Burcu, Szafran, Adam T., Onel, Melis, Stossi, Fabio, Mancini, Maureen G., Lloyd, Dillon, Wright, Fred A., Zhou, Lan, Mancini, Michael A., Pistikopoulos, Efstratios N.
Publicado 2020

Androgen Receptor Mutations Associated with Androgen Insensitivity Syndrome: A High Content Analysis Approach Leading to Personalized Medicine

por Szafran, Adam T., Hartig, Sean, Sun, Huiying, Uray, Ivan P., Szwarc, Maria, Shen, Yuqing, Mediwala, Sanjay N., Bell, Jennifer, McPhaul, Michael J., Mancini, Michael A., Marcelli, Marco
Publicado 2009