Poxvirus-based active immunotherapy synergizes with immune checkpoint inhibitors to cause tumor regression and extend survival in preclinical models of cancer

por Foy, Susan P, Rountree, Ryan B, Cote, Joseph, dela Cruz, Tracy, Gordon, Evan, Trent, Erica, Franzusoff, Alex, Breitmeyer, James B, Mandl, Stefanie J
Publicado 2014

Elucidating immunologic mechanisms of PROSTVAC cancer immunotherapy

por Mandl, Stefanie J, Rountree, Ryan B, dela Cruz, Tracy B, Foy, Susan P, Cote, Joseph J, Gordon, Evan J, Trent, Erica, Delcayre, Alain, Franzusoff, Alex
Publicado 2014

Immunotherapy with MVA-BN(®)-HER2 induces HER-2-specific Th1 immunity and alters the intratumoral balance of effector and regulatory T cells

por Mandl, Stefanie J., Rountree, Ryan B., Dalpozzo, Katie, Do, Lisa, Lombardo, John R., Schoonmaker, Peter L., Dirmeier, Ulrike, Steigerwald, Robin, Giffon, Thierry, Laus, Reiner, Delcayre, Alain
Publicado 2011

Poxvirus-Based Active Immunotherapy with PD-1 and LAG-3 Dual Immune Checkpoint Inhibition Overcomes Compensatory Immune Regulation, Yielding Complete Tumor Regression in Mice

por Foy, Susan P., Sennino, Barbara, dela Cruz, Tracy, Cote, Joseph J., Gordon, Evan J., Kemp, Felicia, Xavier, Veronica, Franzusoff, Alex, Rountree, Ryan B., Mandl, Stefanie J.
Publicado 2016

Poxvirus-based active immunotherapy synergizes with CTLA-4 blockade to increase survival in a murine tumor model by improving the magnitude and quality of cytotoxic T cells

por Foy, Susan P., Mandl, Stefanie J., dela Cruz, Tracy, Cote, Joseph J., Gordon, Evan J., Trent, Erica, Delcayre, Alain, Breitmeyer, James, Franzusoff, Alex, Rountree, Ryan B.
Publicado 2016

Non-viral precision T cell receptor replacement for personalized cell therapy

por Foy, Susan P., Jacoby, Kyle, Bota, Daniela A., Hunter, Theresa, Pan, Zheng, Stawiski, Eric, Ma, Yan, Lu, William, Peng, Songming, Wang, Clifford L., Yuen, Benjamin, Dalmas, Olivier, Heeringa, Katharine, Sennino, Barbara, Conroy, Andy, Bethune, Michael T., Mende, Ines, White, William, Kukreja, Monica, Gunturu, Swetha, Humphrey, Emily, Hussaini, Adeel, An, Duo, Litterman, Adam J., Quach, Boi Bryant, Ng, Alphonsus H. C., Lu, Yue, Smith, Chad, Campbell, Katie M., Anaya, Daniel, Skrdlant, Lindsey, Huang, Eva Yi-Hsuan, Mendoza, Ventura, Mathur, Jyoti, Dengler, Luke, Purandare, Bhamini, Moot, Robert, Yi, Michael C., Funke, Roel, Sibley, Alison, Stallings-Schmitt, Todd, Oh, David Y., Chmielowski, Bartosz, Abedi, Mehrdad, Yuan, Yuan, Sosman, Jeffrey A., Lee, Sylvia M., Schoenfeld, Adam J., Baltimore, David, Heath, James R., Franzusoff, Alex, Ribas, Antoni, Rao, Arati V., Mandl, Stefanie J.
Publicado 2022