TP53 Alterations in Myelodysplastic Syndromes and Acute Myeloid Leukemia

por Rahmé, Ramy, Braun, Thorsten, Manfredi, James J., Fenaux, Pierre
Publicado 2023

Skp2B Overexpression Alters a Prohibitin-p53 Axis and the Transcription of PAPP-A, the Protease of Insulin-Like Growth Factor Binding Protein 4

por Chander, Harish, Halpern, Max, Resnick-Silverman, Lois, Manfredi, James J., Germain, Doris
Publicado 2011

Loss of p53-mediated cell-cycle arrest, senescence and apoptosis promotes genomic instability and premature aging

por Li, Tongyuan, Liu, Xiangyu, Jiang, Le, Manfredi, James, Zha, Shan, Gu, Wei
Publicado 2016

Ash2L enables P53–dependent apoptosis by favoring stable transcription pre–initiation complex formation on its pro-apoptotic target promoters

por Mungamuri, Sathish Kumar, Wang, Shaomeng, Manfredi, James J., Gu, Wei, Aaronson, Stuart A.
Publicado 2014

A novel regulatory circuit between p53 and GFI1 controls induction of apoptosis in T cells

por Vadnais, Charles, Chen, Riyan, Fraszczak, Jennifer, Hamard, Pierre-Jacques, Manfredi, James J., Möröy, Tarik
Publicado 2019

In vivo RNA-seq and ChIP-seq analyses show an obligatory role for the C terminus of p53 in conferring tissue-specific radiation sensitivity

por Resnick-Silverman, Lois, Zhou, Royce, Campbell, Moray J., Leibling, Ian, Parsons, Ramon, Manfredi, James J.
Publicado 2023

Distinct mechanisms control genome recognition by p53 at its target genes linked to different cell fates

por Farkas, Marina, Hashimoto, Hideharu, Bi, Yingtao, Davuluri, Ramana V., Resnick-Silverman, Lois, Manfredi, James J., Debler, Erik W., McMahon, Steven B.
Publicado 2021

The C terminus of p53 regulates gene expression by multiple mechanisms in a target- and tissue-specific manner in vivo

por Hamard, Pierre-Jacques, Barthelery, Nicolas, Hogstad, Brandon, Mungamuri, Sathish Kumar, Tonnessen, Crystal A., Carvajal, Luis A., Senturk, Emir, Gillespie, Virginia, Aaronson, Stuart A., Merad, Miriam, Manfredi, James J.
Publicado 2013