TAK1ng control: TAK1 restrains NLRP3 activation

por Mangan, Matthew Stephen, Latz, Eicke
Publicado 2018

Recent insights into the molecular mechanisms of the NLRP3 inflammasome activation

por Próchnicki, Tomasz, Mangan, Matthew S., Latz, Eicke
Publicado 2016

How location and cellular signaling combine to activate the NLRP3 inflammasome

por Akbal, Anil, Dernst, Alesja, Lovotti, Marta, Mangan, Matthew S. J., McManus, Róisín M., Latz, Eicke
Publicado 2022

Transcriptional licensing is required for Pyrin inflammasome activation in human macrophages and bypassed by mutations causing familial Mediterranean fever

por Mangan, Matthew S. J., Gorki, Friederike, Krause, Karoline, Heinz, Alexander, Pankow, Anne, Ebert, Thomas, Jahn, Dieter, Hiller, Karsten, Hornung, Veit, Maurer, Marcus, Schmidt, Florian I., Gerhard, Ralf, Latz, Eicke
Publicado 2022

Spatiotemporal proteomics uncovers cathepsin-dependent macrophage cell death during Salmonella infection

por Selkrig, Joel, Li, Nan, Hausmann, Annika, Mangan, Matthew S. J., Zietek, Matylda, Mateus, André, Bobonis, Jacob, Sueki, Anna, Imamura, Haruna, El Debs, Bachir, Sigismondo, Gianluca, Florea, Bogdan I., Overkleeft, Herman S., Kopitar-Jerala, Natasa, Turk, Boris, Beltrao, Pedro, Savitski, Mikhail, Latz, Eicke, Hardt, Wolf-Dietrich, Krijgsveld, Jeroen, Typas, Athanasios
Publicado 2020

ASC has extracellular and prionoid activities that propagate inflammation

por Franklin, Bernardo S., Bossaller, Lukas, De Nardo, Dominic, Ratter, Jacqueline M., Stutz, Andrea, Engels, Gudrun, Brenker, Christoph, Nordhoff, Mark, Mirandola, Sandra R., Al-Amoudi, Ashraf, Mangan, Matthew, Zimmer, Sebastian, Monks, Brian, Fricke, Martin, Schmidt, Reinhold E., Espevik, Terje, Jones, Bernadette, Jarnicki, Andrew G., Hansbro, Philip M., Busto, Patricia, Marshak-Rothstein, Ann, Hornemann, Simone, Aguzzi, Adriano, Kastenmüller, Wolfgang, Latz, Eicke
Publicado 2014

BTK operates a phospho-tyrosine switch to regulate NLRP3 inflammasome activity

por Bittner, Zsófia Agnes, Liu, Xiao, Mateo Tortola, Maria, Tapia-Abellán, Ana, Shankar, Sangeetha, Andreeva, Liudmila, Mangan, Matthew, Spalinger, Marianne, Kalbacher, Hubert, Düwell, Peter, Lovotti, Marta, Bosch, Karlotta, Dickhöfer, Sabine, Marcu, Ana, Stevanović, Stefan, Herster, Franziska, Cardona Gloria, Yamel, Chang, Tzu-Hsuan, Bork, Francesca, Greve, Carsten L., Löffler, Markus W., Wolz, Olaf-Oliver, Schilling, Nadine A., Kümmerle-Deschner, Jasmin B., Wagner, Samuel, Delor, Anita, Grimbacher, Bodo, Hantschel, Oliver, Scharl, Michael, Wu, Hao, Latz, Eicke, Weber, Alexander N.R.
Publicado 2021