A Versatile Strategy to Reduce UGA-Selenocysteine Recoding Efficiency of the Ribosome Using CRISPR-Cas9-Viral-Like-Particles Targeting Selenocysteine-tRNA([Ser]Sec) Gene

por Vindry, Caroline, Guillin, Olivia, Mangeot, Philippe E., Ohlmann, Théophile, Chavatte, Laurent
Publicado 2019

A homozygous mutation in the human selenocysteine tRNA gene impairs UGA recoding activity and selenoproteome regulation by selenium

por Vindry, Caroline, Guillin, Olivia, Wolff, Philippe, Marie, Paul, Mortreux, Franck, Mangeot, Philippe E, Ohlmann, Théophile, Chavatte, Laurent
Publicado 2023

A cohesin/HUSH- and LINC-dependent pathway controls ribosomal DNA double-strand break repair

por Marnef, Aline, Finoux, Anne-Laure, Arnould, Coline, Guillou, Emmanuelle, Daburon, Virginie, Rocher, Vincent, Mangeat, Thomas, Mangeot, Philippe E., Ricci, Emiliano P., Legube, Gaëlle
Publicado 2019

Loop extrusion as a mechanism for DNA damage repair foci formation

por Arnould, Coline, Rocher, Vincent, Finoux, Anne-Laure, Clouaire, Thomas, Li, Kevin, Zhou, Felix, Caron, Pierre, Mangeot, Philippe. E., Ricci, Emiliano P., Mourad, Raphael, Haber, James E, Noordermeer, Daan, Legube, Gaëlle
Publicado 2021

Genome editing in primary cells and in vivo using viral-derived Nanoblades loaded with Cas9-sgRNA ribonucleoproteins

por Mangeot, Philippe E., Risson, Valérie, Fusil, Floriane, Marnef, Aline, Laurent, Emilie, Blin, Juliana, Mournetas, Virginie, Massouridès, Emmanuelle, Sohier, Thibault J. M., Corbin, Antoine, Aubé, Fabien, Teixeira, Marie, Pinset, Christian, Schaeffer, Laurent, Legube, Gaëlle, Cosset, François-Loïc, Verhoeyen, Els, Ohlmann, Théophile, Ricci, Emiliano P.
Publicado 2019

Baboon Envelope Pseudotyped “Nanoblades” Carrying Cas9/gRNA Complexes Allow Efficient Genome Editing in Human T, B, and CD34(+) Cells and Knock-in of AAV6-Encoded Donor DNA in CD34...

por Gutierrez-Guerrero, Alejandra, Abrey Recalde, Maria Jimena, Mangeot, Philippe E., Costa, Caroline, Bernadin, Ornellie, Périan, Séverine, Fusil, Floriane, Froment, Gisèle, Martinez-Turtos, Adriana, Krug, Adrien, Martin, Francisco, Benabdellah, Karim, Ricci, Emiliano P., Giovannozzi, Simone, Gijsbers, Rik, Ayuso, Eduard, Cosset, François-Loïc, Verhoeyen, Els
Publicado 2021

IRGM Is a Common Target of RNA Viruses that Subvert the Autophagy Network

por Grégoire, Isabel Pombo, Richetta, Clémence, Meyniel-Schicklin, Laurène, Borel, Sophie, Pradezynski, Fabrine, Diaz, Olivier, Deloire, Alexandre, Azocar, Olga, Baguet, Joël, Le Breton, Marc, Mangeot, Philippe E., Navratil, Vincent, Joubert, Pierre-Emmanuel, Flacher, Monique, Vidalain, Pierre-Olivier, André, Patrice, Lotteau, Vincent, Biard-Piechaczyk, Martine, Rabourdin-Combe, Chantal, Faure, Mathias
Publicado 2011

Nanoblades allow high-level genome editing in murine and human organoids

por Tiroille, Victor, Krug, Adrien, Bokobza, Emma, Kahi, Michel, Bulcaen, Mattijs, Ensinck, Marjolein M., Geurts, Maarten H., Hendriks, Delilah, Vermeulen, François, Larbret, Frédéric, Gutierrez-Guerrero, Alejandra, Chen, Yu, Van Zundert, Indra, Rocha, Susana, Rios, Anne C., Medaer, Louise, Gijsbers, Rik, Mangeot, Philippe E., Clevers, Hans, Carlon, Marianne S., Bost, Frédéric, Verhoeyen, Els
Publicado 2023