Functional role of voltage gated Ca(2+) channels in heart automaticity

por Mesirca, Pietro, Torrente, Angelo G., Mangoni, Matteo E.
Publicado 2015

Ca(V)1.3 L-type Ca(2+) channel contributes to the heartbeat by generating a dihydropyridine-sensitive persistent Na(+) current

por Toyoda, Futoshi, Mesirca, Pietro, Dubel, Stefan, Ding, Wei-Guang, Striessnig, Joerg, Mangoni, Matteo E., Matsuura, Hiroshi
Publicado 2017

Electrophysiological and Molecular Mechanisms of Sinoatrial Node Mechanosensitivity

por Turner, Daniel, Kang, Chen, Mesirca, Pietro, Hong, Juan, Mangoni, Matteo E., Glukhov, Alexey V., Sah, Rajan
Publicado 2021

Genetic Complexity of Sinoatrial Node Dysfunction

por Wallace, Michael J., El Refaey, Mona, Mesirca, Pietro, Hund, Thomas J., Mangoni, Matteo E., Mohler, Peter J.
Publicado 2021

Clock-dependent and system-driven oscillators interact in the suprachiasmatic nuclei to pace mammalian circadian rhythms

por Abitbol, Karine, Debiesse, Ségolène, Molino, François, Mesirca, Pietro, Bidaud, Isabelle, Minami, Yoichi, Mangoni, Matteo E., Yagita, Kazuhiro, Mollard, Patrice, Bonnefont, Xavier
Publicado 2017

L-Type Ca(v)1.3 Calcium Channels Are Required for Beta-Adrenergic Triggered Automaticity in Dormant Mouse Sinoatrial Pacemaker Cells

por Louradour, Julien, Bortolotti, Olivier, Torre, Eleonora, Bidaud, Isabelle, Lamb, Ned, Fernandez, Anne, Le Guennec, Jean-Yves, Mangoni, Matteo E., Mesirca, Pietro
Publicado 2022

Concomitant genetic ablation of L-type Ca(v)1.3 (α(1D)) and T-type Ca(v)3.1 (α(1G)) Ca(2+) channels disrupts heart automaticity

por Baudot, Matthias, Torre, Eleonora, Bidaud, Isabelle, Louradour, Julien, Torrente, Angelo G., Fossier, Lucile, Talssi, Leïla, Nargeot, Joël, Barrère-Lemaire, Stéphanie, Mesirca, Pietro, Mangoni, Matteo E.
Publicado 2020

Functional Properties of a Newly Identified C-terminal Splice Variant of Ca(v)1.3 L-type Ca(2+) Channels

por Bock, Gabriella, Gebhart, Mathias, Scharinger, Anja, Jangsangthong, Wanchana, Busquet, Perrine, Poggiani, Chiara, Sartori, Simone, Mangoni, Matteo E., Sinnegger-Brauns, Martina J., Herzig, Stefan, Striessnig, Jörg, Koschak, Alexandra
Publicado 2011

Inhibition of G protein-gated K(+) channels by tertiapin-Q rescues sinus node dysfunction and atrioventricular conduction in mouse models of primary bradycardia

por Bidaud, Isabelle, Chong, Antony Chung You, Carcouet, Agnes, Waard, Stephan De, Charpentier, Flavien, Ronjat, Michel, Waard, Michel De, Isbrandt, Dirk, Wickman, Kevin, Vincent, Anne, Mangoni, Matteo E., Mesirca, Pietro
Publicado 2020

A synthetic peptide that prevents cAMP regulation in mammalian hyperpolarization-activated cyclic nucleotide-gated (HCN) channels

por Saponaro, Andrea, Cantini, Francesca, Porro, Alessandro, Bucchi, Annalisa, DiFrancesco, Dario, Maione, Vincenzo, Donadoni, Chiara, Introini, Bianca, Mesirca, Pietro, Mangoni, Matteo E, Thiel, Gerhard, Banci, Lucia, Santoro, Bina, Moroni, Anna
Publicado 2018

Characterization of sinoatrial automaticity in Microcebus murinus to study the effect of aging on cardiac activity and the correlation with longevity

por DiFrancesco, Mattia L., Marrot, Manon, Torre, Eleonora, Mesirca, Pietro, Davaze, Romain, Lautier, Corinne, Fontes, Pascaline, Cuoq, Joël, Fernandez, Anne, Lamb, Ned, Pifferi, Fabien, Mestre-Francés, Nadine, Mangoni, Matteo E., Torrente, Angelo G.
Publicado 2023

Genetic Ablation of G Protein-Gated Inwardly Rectifying K(+) Channels Prevents Training-Induced Sinus Bradycardia

por Bidaud, Isabelle, D’Souza, Alicia, Forte, Gabriella, Torre, Eleonora, Greuet, Denis, Thirard, Steeve, Anderson, Cali, Chung You Chong, Antony, Torrente, Angelo G., Roussel, Julien, Wickman, Kevin, Boyett, Mark R., Mangoni, Matteo E., Mesirca, Pietro
Publicado 2021

Optical Control of Cardiac Rhythm by In Vivo Photoactivation of an ERG Channel Peptide Inhibitor

por Montnach, Jérôme, Millet, Hugo, Persello, Antoine, Meudal, Hervé, De Waard, Stephan, Mesrica, Pietro, Ribeiro, Barbara, Richard, Jérémie, Hivonnait, Agnès, Tessier, Agnès, Lauzier, Benjamin, Charpentier, Flavien, Mangoni, Matteo E., Landon, Céline, Jopling, Chris, De Waard, Michel
Publicado 2023

The G-protein–gated K(+) channel, I(KACh), is required for regulation of pacemaker activity and recovery of resting heart rate after sympathetic stimulation

por Mesirca, Pietro, Marger, Laurine, Toyoda, Futoshi, Rizzetto, Riccardo, Audoubert, Matthieu, Dubel, Stefan, Torrente, Angelo G., DiFrancesco, Mattia L., Muller, Jana Christina, Leoni, Anne-Laure, Couette, Brigitte, Nargeot, Joël, Clapham, David E., Wickman, Kevin, Mangoni, Matteo E.
Publicado 2013

Cardiac arrhythmia induced by genetic silencing of “funny” (f) channels is rescued by GIRK4 inactivation

por Mesirca, Pietro, Alig, Jacqueline, Torrente, Angelo G., Müller, Jana Christina, Marger, Laurine, Rollin, Anne, Marquilly, Claire, Vincent, Anne, Dubel, Stefan, Bidaud, Isabelle, Fernandez, Anne, Seniuk, Anika, Engeland, Birgit, Singh, Jasmin, Miquerol, Lucile, Ehmke, Heimo, Eschenhagen, Thomas, Nargeot, Joel, Wickman, Kevin, Isbrandt, Dirk, Mangoni, Matteo E.
Publicado 2014

Impact of stress on cardiac phenotypes in mice harboring an ankyrin-B disease variant

por Wallace, Michael J., Malhotra, Nipun, Mariángelo, Juan Ignacio Elio, Stevens, Tyler L., Young, Lindsay J., Antwi-Boasiako, Steve, Abdallah, Danielle, Takenaka, Sarah Sumie, Cavus, Omer, Murphy, Nathaniel P., Han, Mei, Xu, Xianyao, Mangoni, Matteo E., Hund, Thomas J., Roberts, Jason D., Györke, Sandor, Mohler, Peter J., El Refaey, Mona
Publicado 2023

A circadian clock in the sinus node mediates day-night rhythms in Hcn4 and heart rate

por D’Souza, Alicia, Wang, Yanwen, Anderson, Cali, Bucchi, Annalisa, Baruscotti, Mirko, Olieslagers, Servé, Mesirca, Pietro, Johnsen, Anne Berit, Mastitskaya, Svetlana, Ni, Haibo, Zhang, Yu, Black, Nicholas, Cox, Charlotte, Wegner, Sven, Bano-Otalora, Beatriz, Petit, Cheryl, Gill, Eleanor, Logantha, Sunil Jit R.J., Dobrzynski, Halina, Ashton, Nick, Hart, George, Zhang, Rai, Zhang, Henggui, Cartwright, Elizabeth J., Wisloff, Ulrik, Mangoni, Matteo E., da Costa Martins, Paula A., Piggins, Hugh D., DiFrancesco, Dario, Boyett, Mark R.
Publicado 2021