Polo-like kinase inhibitor volasertib marginally enhances the efficacy of the novel Fc-engineered anti-CD33 antibody BI 836858 in acute myeloid leukemia

por Gopalakrishnan, Bhavani, Cheney, Carolyn, Mani, Rajeswaran, Mo, Xiaokui, Bucci, Donna, Walker, Alison, Klisovic, Rebecca, Bhatnagar, Bhavana, Walsh, Katherine, Rueter, Bjoern, Waizenegger, Irene C., Heider, Karl-Heinz, Blum, William, Vasu, Sumithira, Muthusamy, Natarajan
Publicado 2018

The interleukin-3 receptor CD123 targeted SL-401 mediates potent cytotoxic activity against CD34(+)CD123(+) cells from acute myeloid leukemia/myelodysplastic syndrome patients and...

por Mani, Rajeswaran, Goswami, Swagata, Gopalakrishnan, Bhavani, Ramaswamy, Rahul, Wasmuth, Ronni, Tran, Minh, Mo, Xiaokui, Gordon, Amber, Bucci, Donna, Lucas, David M., Mims, Alice, Brooks, Christopher, Dorrance, Adrienne, Walker, Alison, Blum, William, Byrd, John C., Lozanski, Gerard, Vasu, Sumithira, Muthusamy, Natarajan
Publicado 2018

Tumor antigen ROR1 targeted drug delivery mediated selective leukemic but not normal B cell cytotoxicity in chronic lymphocytic leukemia

por Mani, Rajeswaran, Mao, Yicheng, Frissora, Frank W., Chiang, Chi-Ling, Wang, Jiang, Zhao, Yuan, Wu, Yun, Yu, Bo, Yan, Ribai, Mo, Xiaokui, Yu, Lianbo, Flynn, Joseph, Jones, Jeffrey, Andritsos, Leslie, Baskar, Sivasubramanian, Rader, Christoph, Phelps, Mitch A, Chen, Ching-Shih, Lee, Robert J., Byrd, John C., Lee, L. James, Muthusamy, Natarajan
Publicado 2014

Oxidative stress-induced JNK/AP-1 signaling is a major pathway involved in selective apoptosis of myelodysplastic syndrome cells by Withaferin-A

por Oben, Karine Z., Alhakeem, Sara S., McKenna, Mary K., Brandon, Jason A., Mani, Rajeswaran, Noothi, Sunil K., Jinpeng, Liu, Akunuru, Shailaja, Dhar, Sanjit K., Singh, Inder P., Liang, Ying, Wang, Chi, Abdel-Latif, Ahmed, Stills Jr, Harold F., St. Clair, Daret K., Geiger, Hartmut, Muthusamy, Natarajan, Tohyama, Kaoru, Gupta, Ramesh C., Bondada, Subbarao
Publicado 2017

PP2A is a therapeutically targetable driver of cell fate decisions via a c-Myc/p21 axis in human and murine acute myeloid leukemia

por Goswami, Swagata, Mani, Rajeswaran, Nunes, Jessica, Chiang, Chi-Ling, Zapolnik, Kevan, Hu, Eileen, Frissora, Frank, Mo, Xiaokui, Walker, Logan A., Yan, Pearlly, Bundschuh, Ralf, Beaver, Larry, Devine, Raymond, Tsai, Yo-Ting, Ventura, Ann, Xie, Zhiliang, Chen, Min, Lapalombella, Rosa, Walker, Alison, Mims, Alice, Larkin, Karilyn, Grieselhuber, Nicole, Bennett, Chad, Phelps, Mitch, Hertlein, Erin, Behbehani, Gregory, Vasu, Sumithira, Byrd, John C., Muthusamy, Natarajan
Publicado 2022