Impaired B cell anergy is not sufficient to breach tolerance to nuclear antigen in Vκ8/3H9 lupus-prone mice

por Manion, Kieran P., Baglaenko, Yuriy, Chang, Nan-Hua, Talaei, Nafiseh, Wither, Joan E.
Publicado 2020

IL-10 Production Is Critical for Sustaining the Expansion of CD5(+) B and NKT Cells and Restraining Autoantibody Production in Congenic Lupus-Prone Mice

por Baglaenko, Yuriy, Manion, Kieran P., Chang, Nan-Hua, Gracey, Eric, Loh, Christina, Wither, Joan E.
Publicado 2016

Multiple tolerance defects contribute to the breach of B cell tolerance in New Zealand Black chromosome 1 congenic mice

por Chang, Nan-Hua, Manion, Kieran P., Loh, Christina, Pau, Evelyn, Baglaenko, Yuriy, Wither, Joan E.
Publicado 2017

Altered Balance of Pro-Inflammatory Immune Cells to T Regulatory Cells Differentiates Symptomatic From Asymptomatic Individuals With Anti-Nuclear Antibodies

por Gupta, Rashi, Vanlieshout, Emma, Manion, Kieran, Bonilla, Dennisse, Kim, Michael, Muñoz-Grajales, Carolina, Nassar, Carol, Johnson, Sindhu R., Hiraki, Linda T., Ahmad, Zareen, Touma, Zahi, Bookman, Arthur, Wither, Joan E.
Publicado 2022

The presence of anti-nuclear antibodies alone is associated with changes in B cell activation and T follicular helper cells similar to those in systemic autoimmune rheumatic diseas...

por Baglaenko, Yuriy, Chang, Nan-Hua, Johnson, Sindhu R., Hafiz, Waleed, Manion, Kieran, Ferri, Dario, Noamani, Babak, Bonilla, Dennisse, Rusta-Sellehy, Sina, Lisnevskaia, Larissa, Silverman, Earl, Bookman, Arthur, Landolt-Marticorena, Carolina, Wither, Joan
Publicado 2018

Apoptotic cell–induced, TLR9-dependent AhR activity is required for immunological tolerance and suppression of systemic lupus erythematosus in mice and humans

por Shinde, Rahul, Hezaveh, Kebria, Halaby, Marie Jo, Kloetgen, Andreas, Chakravarthy, Ankur, da Silva Medina, Tiago, Deol, Reema, Manion, Kieran P., Baglaenko, Yuriy, Eldh, Maria, Lamorte, Sara, Wallace, Drew, Chodisetti, Sathi Babu, Ravishankar, Buvana, Liu, Haiyun, Chaudhary, Kapil, Munn, David H., Tsirigos, Aristotelis, Madaio, Michael, Gabrielsson, Susanne, Touma, Zahi, Wither, Joan, De Carvalho, Daniel D., McGaha, Tracy L.
Publicado 2018