Robust activation of microhomology-mediated end joining for precision gene editing applications

por Ata, Hirotaka, Ekstrom, Thomas L., Martínez-Gálvez, Gabriel, Mann, Carla M., Dvornikov, Alexey V., Schaefbauer, Kyle J., Ma, Alvin C., Dobbs, Drena, Clark, Karl J., Ekker, Stephen C.
Publicado 2018

The Gene Sculpt Suite: a set of tools for genome editing

por Mann, Carla M, Martínez-Gálvez, Gabriel, Welker, Jordan M, Wierson, Wesley A, Ata, Hirotaka, Almeida, Maira P, Clark, Karl J, Essner, Jeffrey J, McGrail, Maura, Ekker, Stephen C, Dobbs, Drena
Publicado 2019

Expanding the CRISPR Toolbox with ErCas12a in Zebrafish and Human Cells

por Wierson, Wesley A., Simone, Brandon W., WareJoncas, Zachary, Mann, Carla, Welker, Jordan M., Kar, Bibekananda, Emch, Michael J., Friedberg, Iddo, Gendron, William A.C., Barry, Michael A., Clark, Karl J., Dobbs, Drena L., McGrail, Maura A., Ekker, Stephen C., Essner, Jeffrey J.
Publicado 2019

GenSLMs: Genome-scale language models reveal SARS-CoV-2 evolutionary dynamics

por Zvyagin, Maxim, Brace, Alexander, Hippe, Kyle, Deng, Yuntian, Zhang, Bin, Bohorquez, Cindy Orozco, Clyde, Austin, Kale, Bharat, Perez-Rivera, Danilo, Ma, Heng, Mann, Carla M., Irvin, Michael, Pauloski, J. Gregory, Ward, Logan, Hayot-Sasson, Valerie, Emani, Murali, Foreman, Sam, Xie, Zhen, Lin, Diangen, Shukla, Maulik, Nie, Weili, Romero, Josh, Dallago, Christian, Vahdat, Arash, Xiao, Chaowei, Gibbs, Thomas, Foster, Ian, Davis, James J., Papka, Michael E., Brettin, Thomas, Stevens, Rick, Anandkumar, Anima, Vishwanath, Venkatram, Ramanathan, Arvind
Publicado 2022

Efficient targeted integration directed by short homology in zebrafish and mammalian cells

por Wierson, Wesley A, Welker, Jordan M, Almeida, Maira P, Mann, Carla M, Webster, Dennis A, Torrie, Melanie E, Weiss, Trevor J, Kambakam, Sekhar, Vollbrecht, Macy K, Lan, Merrina, McKeighan, Kenna C, Levey, Jacklyn, Ming, Zhitao, Wehmeier, Alec, Mikelson, Christopher S, Haltom, Jeffrey A, Kwan, Kristen M, Chien, Chi-Bin, Balciunas, Darius, Ekker, Stephen C, Clark, Karl J, Webber, Beau R, Moriarity, Branden S, Solin, Stacy L, Carlson, Daniel F, Dobbs, Drena L, McGrail, Maura, Essner, Jeffrey
Publicado 2020