Redox status in mammalian cells and stem cells during culture in vitro: Critical roles of Nrf2 and cystine transporter activity in the maintenance of redox balance

por Ishii, Tetsuro, Mann, Giovanni E.
Publicado 2014

When and how does brain-derived neurotrophic factor activate Nrf2 in astrocytes and neurons?

por Ishii, Tetsuro, Mann, Giovanni E.
Publicado 2018

Mechanisms underlying unidirectional laminar shear stress-mediated Nrf2 activation in endothelial cells: Amplification of low shear stress signaling by primary cilia

por Ishii, Tetsuro, Warabi, Eiji, Mann, Giovanni E.
Publicado 2021

Stress Activated MAP Kinases and Cyclin-Dependent Kinase 5 Mediate Nuclear Translocation of Nrf2 via Hsp90α-Pin1-Dynein Motor Transport Machinery

por Ishii, Tetsuro, Warabi, Eiji, Mann, Giovanni E.
Publicado 2023

Effects of 4-hydroxynonenal on vascular endothelial and smooth muscle cell redox signaling and function in health and disease()

por Chapple, Sarah J., Cheng, Xinghua, Mann, Giovanni E.
Publicado 2013

Heme Oxygenase Dependent Bilirubin Generation in Vascular Cells: A Role in Preventing Endothelial Dysfunction in Local Tissue Microenvironment?

por Nitti, Mariapaola, Furfaro, Anna Lisa, Mann, Giovanni E.
Publicado 2020

Control of Redox Homeostasis by Short-Chain Fatty Acids: Implications for the Prevention and Treatment of Breast Cancer

por González-Bosch, Carmen, Zunszain, Patricia A., Mann, Giovanni E.
Publicado 2023

Short-chain fatty acids as modulators of redox signaling in health and disease

por González-Bosch, Carmen, Boorman, Emily, Zunszain, Patricia A., Mann, Giovanni E.
Publicado 2021

A PP2A-mediated feedback mechanism controls Ca(2+)-dependent NO synthesis under physiological oxygen

por Keeley, Thomas P., Siow, Richard C. M., Jacob, Ron, Mann, Giovanni E.
Publicado 2017

Reduced SERCA activity underlies dysregulation of Ca(2+) homeostasis under atmospheric O(2) levels

por Keeley, Thomas P., Siow, Richard C. M., Jacob, Ron, Mann, Giovanni E.
Publicado 2018

Redox Regulation of Microvascular Permeability: IL-1β Potentiation of Bradykinin-Induced Permeability Is Prevented by Simvastatin

por Freitas, Felipe, Tibiriçá, Eduardo, Singh, Mita, Fraser, Paul A., Mann, Giovanni E.
Publicado 2020

Cardioprotective effects of Cu((II))ATSM in human vascular smooth muscle cells and cardiomyocytes mediated by Nrf2 and DJ-1

por Srivastava, Salil, Blower, Philip J., Aubdool, Aisah A., Hider, Robert C., Mann, Giovanni E., Siow, Richard C.
Publicado 2016

The anti‐ageing hormone klotho induces Nrf2‐mediated antioxidant defences in human aortic smooth muscle cells

por Maltese, Giuseppe, Psefteli, Paraskevi‐Maria, Rizzo, Benedetta, Srivastava, Salil, Gnudi, Luigi, Mann, Giovanni E., Siow, Richard C.M.
Publicado 2016

Nox4 regulates Nrf2 and glutathione redox in cardiomyocytes in vivo

por Brewer, Alison C., Murray, Thomas V.A., Arno, Matthew, Zhang, Min, Anilkumar, Narayana P., Mann, Giovanni E., Shah, Ajay M.
Publicado 2011

Nrf2-regulated redox signaling in brain endothelial cells adapted to physiological oxygen levels: Consequences for sulforaphane mediated protection against hypoxia-reoxygenation

por Warpsinski, Gabriela, Smith, Matthew J., Srivastava, Salil, Keeley, Thomas P., Siow, Richard C.M., Fraser, Paul A., Mann, Giovanni E.
Publicado 2020

Glycocalyx sialic acids regulate Nrf2-mediated signaling by fluid shear stress in human endothelial cells

por Psefteli, Paraskevi-Maria, Kitscha, Phoebe, Vizcay, Gema, Fleck, Roland, Chapple, Sarah J., Mann, Giovanni E., Fowler, Mark, Siow, Richard C.
Publicado 2020

Sulforaphane induced NRF2 activation in obese pregnancy attenuates developmental redox imbalance and improves early-life cardiovascular function in offspring

por Psefteli, Paraskevi-Maria, Morris, Jessica K., Ehler, Elisabeth, Smith, Lorna, Bowe, James, Mann, Giovanni E., Taylor, Paul D., Chapple, Sarah J.
Publicado 2023

Gestational Diabetes Mellitus Impairs Nrf2-Mediated Adaptive Antioxidant Defenses and Redox Signaling in Fetal Endothelial Cells In Utero

por Cheng, Xinghua, Chapple, Sarah J., Patel, Bijal, Puszyk, William, Sugden, David, Yin, Xiaoke, Mayr, Manuel, Siow, Richard C.M., Mann, Giovanni E.
Publicado 2013

Redox and metal profiles in human coronary endothelial and smooth muscle cells under hyperoxia, physiological normoxia and hypoxia: Effects of NRF2 signaling on intracellular zinc

por Smith, Matthew J., Yang, Fan, Griffiths, Alexander, Morrell, Alexander, Chapple, Sarah J., Siow, Richard C.M., Stewart, Theodora, Maret, Wolfgang, Mann, Giovanni E.
Publicado 2023

Vascular protection afforded by zinc supplementation in human coronary artery smooth muscle cells mediated by NRF2 signaling under hypoxia/reoxygenation

por Yang, Fan, Smith, Matthew J., Griffiths, Alexander, Morrell, Alexander, Chapple, Sarah J., Siow, Richard C.M., Stewart, Theodora, Maret, Wolfgang, Mann, Giovanni E.
Publicado 2023