Absorption, Distribution, and Excretion of (14)C-APX001 after Single-Dose Administration to Rats and Monkeys

por Mansbach, Robert, Shaw, Karen J, Hodges, Michael R, Coleman, Samantha, Fitzsimmons, Michael E
Publicado 2017

Significantly Improved Pharmacokinetics Enhances In Vivo Efficacy of APX001 against Echinocandin- and Multidrug-Resistant Candida Isolates in a Mouse Model of Invasive Candidiasis

por Zhao, Yanan, Lee, Min Hee, Paderu, Padmaja, Lee, Annie, Jimenez-Ortigosa, Cristina, Park, Steven, Mansbach, Robert S., Shaw, Karen Joy, Perlin, David S.
Publicado 2018

Efficacy of APX2039 in a Rabbit Model of Cryptococcal Meningitis

por Giamberardino, Charles D., Schell, Wiley A., Tenor, Jennifer L., Toffaletti, Dena L., Palmucci, Julia R., Marius, Choiselle, Boua, Jane-Valeriane K., Soltow, Quinlyn, Mansbach, Robert, Moseley, M. Arthur, Thompson, J. Will, Dubois, Laura G., Hope, William, Perfect, John R., Shaw, Karen Joy
Publicado 2022