Information for Patients about Inflammatory Bowel Disease

por Mansfield, John C, Tanner, Andrew R, Bramble, Michael G
Publicado 1997

T Lymphocytes Expressing AlphaE Beta7 Integrin in Ulcerative Colitis: Associations With Cellular Lineage and Phenotype

por Lamb, Christopher A, Kirby, John A, Keir, Mary E, Mansfield, John C
Publicado 2017

The Importance of Molecular Immune Investigation in Therapeutic Clinical Development for Biomarker Assessment

por Lamb, Christopher A, Mansfield, John C, Kirby, John A, Keir, Mary E
Publicado 2019

Sexually transmitted infections manifesting as proctitis

por Lamb, Chris A, Lamb, Elizabeth Iris Mary, Mansfield, John C, Sankar, K Nathan
Publicado 2013

Oral Ferric Maltol Does Not Adversely Affect the Intestinal Microbiome of Patients or Mice, but Ferrous Sulphate Does

por Mahalhal, Awad, Frau, Alessandra, Burkitt, Michael D., Ijaz, Umer Z., Lamb, Christopher A., Mansfield, John C., Lewis, Stephen, Pritchard, D. Mark, Probert, Chris S.
Publicado 2021

Dose escalation randomised study of efmarodocokin alfa in healthy volunteers and patients with ulcerative colitis

por Wagner, Frank, Mansfield, John C, Lekkerkerker, Annemarie N, Wang, Yehong, Keir, Mary, Dash, Ajit, Butcher, Brandon, Harder, Brandon, Orozco, Luz D, Mar, Jordan S, Chen, Hao, Rothenberg, Michael E
Publicado 2023

AlphaE Integrin Expression Is Increased in the Ileum Relative to the Colon and Unaffected by Inflammation

por Ichikawa, Ryan, Lamb, Christopher A, Eastham-Anderson, Jeff, Scherl, Alexis, Raffals, Laura, Faubion, William A, Bennett, Miriam R, Long, Anna K, Mansfield, John C, Kirby, John A, Keir, Mary E
Publicado 2018

Conserved γδ T cell selection by BTNL proteins limits progression of human inflammatory bowel disease

por Dart, Robin J, Zlatareva, Iva, Vantourout, Pierre, Theodoridis, Efstathios, Amar, Ariella, Kannambath, Shichina, East, Philip, Recaldin, Timothy, Mansfield, John C, Lamb, Christopher A, Parkes, Miles, Irving, Peter M, Prescott, Natalie J, Hayday, Adrian C
Publicado 2023

The Impact of NOD2 Genetic Variants on the Gut Mycobiota in Crohn’s Disease Patients in Remission and in Individuals Without Gastrointestinal Inflammation

por Nelson, Andrew, Stewart, Christopher J, Kennedy, Nicholas A, Lodge, John K, Tremelling, Mark, Probert, Chris S, Parkes, Miles, Mansfield, John C, Smith, Darren L, Hold, Georgina L, Lees, Charlie W, Bridge, Simon H, Lamb, Christopher A
Publicado 2020

Exome Sequencing and Genotyping Identify a Rare Variant in NLRP7 Gene Associated With Ulcerative Colitis

por Onoufriadis, Alexandros, Stone, Kristina, Katsiamides, Antreas, Amar, Ariella, Omar, Yasmin, de Lange, Katrina M, Taylor, Kirstin, Barrett, Jeffrey C, Pollok, Richard, Hayee, Bu’Hussain, Mansfield, John C, Sanderson, Jeremy D, Simpson, Michael A, Mathew, Christopher G, Prescott, Natalie J
Publicado 2018

A randomised phase I study of etrolizumab (rhuMAb β7) in moderate to severe ulcerative colitis

por Rutgeerts, Paul J, Fedorak, Richard N, Hommes, Daan W, Sturm, Andreas, Baumgart, Daniel C, Bressler, Brian, Schreiber, Stefan, Mansfield, John C, Williams, Marna, Tang, Meina, Visich, Jennifer, Wei, Xiaohui, Keir, Mary, Luca, Diana, Danilenko, Dimitri, Egen, Jackson, O'Byrne, Sharon
Publicado 2013

αEβ7 Integrin Identifies Subsets of Pro-Inflammatory Colonic CD4+ T Lymphocytes in Ulcerative Colitis

por Lamb, Christopher A., Mansfield, John C., Tew, Gaik W., Gibbons, Deena, Long, Anna K., Irving, Peter, Diehl, Lauri, Eastham-Anderson, Jeff, Price, Maria B., O’Boyle, Graeme, Jones, David E. J., O’Byrne, Sharon, Hayday, Adrian, Keir, Mary E., Egen, Jackson G., Kirby, John A.
Publicado 2017

Regulation and Role of αE Integrin and Gut Homing Integrins in Migration and Retention of Intestinal Lymphocytes during Inflammatory Bowel Disease

por Keir, Mary E., Fuh, Franklin, Ichikawa, Ryan, Acres, Meghan, Hackney, Jason A., Hulme, Gillian, Carey, Christopher D., Palmer, Jeremy, Jones, Claire J., Long, Anna K., Jiang, Jenny, Klabunde, Sha, Mansfield, John C., Looney, Cary M., Faubion, William A., Filby, Andrew, Kirby, John A., McBride, Jacqueline, Lamb, Christopher A.
Publicado 2021

Independent and population-specific association of risk variants at the IRGM locus with Crohn's disease

por Prescott, Natalie J., Dominy, Katherine M., Kubo, Michiaki, Lewis, Cathryn M., Fisher, Sheila A., Redon, Richard, Huang, Ni, Stranger, Barbara E., Blaszczyk, Katarzyna, Hudspith, Barry, Parkes, Gareth, Hosono, Naoya, Yamazaki, Keiko, Onnie, Clive M., Forbes, Alastair, Dermitzakis, Emmanouil T., Nakamura, Yusuke, Mansfield, John C., Sanderson, Jeremy, Hurles, Matthew E., Roberts, Roland G., Mathew, Christopher G.
Publicado 2010

Human SNP Links Differential Outcomes in Inflammatory and Infectious Disease to a FOXO3-Regulated Pathway

por Lee, James C., Espéli, Marion, Anderson, Carl A., Linterman, Michelle A., Pocock, Joanna M., Williams, Naomi J., Roberts, Rebecca, Viatte, Sebastien, Fu, Bo, Peshu, Norbert, Hien, Tran Tinh, Phu, Nguyen Hoan, Wesley, Emma, Edwards, Cathryn, Ahmad, Tariq, Mansfield, John C., Gearry, Richard, Dunstan, Sarah, Williams, Thomas N., Barton, Anne, Vinuesa, Carola G., Parkes, Miles, Lyons, Paul A., Smith, Kenneth G.C.
Publicado 2013

Pooled Sequencing of 531 Genes in Inflammatory Bowel Disease Identifies an Associated Rare Variant in BTNL2 and Implicates Other Immune Related Genes

por Prescott, Natalie J., Lehne, Benjamin, Stone, Kristina, Lee, James C., Taylor, Kirstin, Knight, Jo, Papouli, Efterpi, Mirza, Muddassar M., Simpson, Michael A., Spain, Sarah L., Lu, Grace, Fraternali, Franca, Bumpstead, Suzannah J., Gray, Emma, Amar, Ariella, Bye, Hannah, Green, Peter, Chung-Faye, Guy, Hayee, Bu’Hussain, Pollok, Richard, Satsangi, Jack, Parkes, Miles, Barrett, Jeffrey C., Mansfield, John C., Sanderson, Jeremy, Lewis, Cathryn M., Weale, Michael E., Schlitt, Thomas, Mathew, Christopher G.
Publicado 2015

Exploring the genetic architecture of inflammatory bowel disease by whole genome sequencing identifies association at ADCY7

por Luo, Yang, de Lange, Katrina M., Jostins, Luke, Moutsianas, Loukas, Randall, Joshua, Kennedy, Nicholas A., Lamb, Christopher A., McCarthy, Shane, Ahmad, Tariq, Edwards, Cathryn, Serra, Eva Goncalves, Hart, Ailsa, Hawkey, Chris, Mansfield, John C., Mowat, Craig, Newman, William G., Nichols, Sam, Pollard, Martin, Satsangi, Jack, Simmons, Alison, Tremelling, Mark, Uhlig, Holm, Wilson, David C., Lee, James C., Prescott, Natalie J., Lees, Charlie W., Mathew, Christopher G., Parkes, Miles, Barrett, Jeffrey C., Anderson, Carl A.
Publicado 2017

Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease

por de Lange, Katrina M., Moutsianas, Loukas, Lee, James C., Lamb, Christopher A., Luo, Yang, Kennedy, Nicholas A., Jostins, Luke, Rice, Daniel L., Gutierrez-Achury, Javier, Ji, Sun-Gou, Heap, Graham, Nimmo, Elaine R., Edwards, Cathryn, Henderson, Paul, Mowat, Craig, Sanderson, Jeremy, Satsangi, Jack, Simmons, Alison, Wilson, David C., Tremelling, Mark, Hart, Ailsa, Mathew, Christopher G., Newman, William G., Parkes, Miles, Lees, Charlie W., Uhlig, Holm, Hawkey, Chris, Prescott, Natalie J., Ahmad, Tariq, Mansfield, John C., Anderson, Carl A., Barrett, Jeffrey C.
Publicado 2017

Negligible impact of rare autoimmune-locus coding-region variants on missing heritability

por Hunt, Karen A, Mistry, Vanisha, Bockett, Nicholas A, Ahmad, Tariq, Ban, Maria, Barker, Jonathan N, Barrett, Jeffrey C, Blackburn, Hannah, Brand, Oliver, Burren, Oliver, Capon, Francesca, Compston, Alastair, Gough, Stephen CL, Jostins, Luke, Kong, Yong, Lee, James C, Lek, Monkol, MacArthur, Daniel G, Mansfield, John C, Mathew, Christopher G, Mein, Charles A, Mirza, Muddassar, Nutland, Sarah, Onengut-Gumuscu, Suna, Papouli, Efterpi, Parkes, Miles, Rich, Stephen S., Sawcer, Steven, Satsangi, Jack, Simmonds, Matthew J, Trembath, Richard C, Walker, Neil M, Wozniak, Eva, Todd, John A, Simpson, Michael A, Plagnol, Vincent, van Heel, David A
Publicado 2013

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

por Anderson, Carl A., Boucher, Gabrielle, Lees, Charlie W., Franke, Andre, D’Amato, Mauro, Taylor, Kent D., Lee, James C., Goyette, Philippe, Imielinski, Marcin, Latiano, Anna, Lagacé, Caroline, Scott, Regan, Amininejad, Leila, Bumpstead, Suzannah, Baidoo, Leonard, Baldassano, Robert N., Barclay, Murray, Bayless, Theodore M., Brand, Stephan, Büning, Carsten, Colombel, Jean-Frédéric, Denson, Lee A., De Vos, Martine, Dubinsky, Marla, Edwards, Cathryn, Ellinghaus, David, Fehrmann, Rudolf S.N., Floyd, James A.B., Florin, Tim, Franchimont, Denis, Franke, Lude, Georges, Michel, Glas, Jürgen, Glazer, Nicole L., Guthery, Stephen L., Haritunians, Talin, Hayward, Nicholas K., Hugot, Jean-Pierre, Jobin, Gilles, Laukens, Debby, Lawrance, Ian, Lémann, Marc, Levine, Arie, Libioulle, Cecile, Louis, Edouard, McGovern, Dermot P., Milla, Monica, Montgomery, Grant W., Morley, Katherine I., Mowat, Craig, Ng, Aylwin, Newman, William, Ophoff, Roel A, Papi, Laura, Palmieri, Orazio, Peyrin-Biroulet, Laurent, Panés, Julián, Phillips, Anne, Prescott, Natalie J., Proctor, Deborah D., Roberts, Rebecca, Russell, Richard, Rutgeerts, Paul, Sanderson, Jeremy, Sans, Miquel, Schumm, Philip, Seibold, Frank, Sharma, Yashoda, Simms, Lisa, Seielstad, Mark, Steinhart, A. Hillary, Targan, Stephan R., van den Berg, Leonard H., Vatn, Morten, Verspaget, Hein, Walters, Thomas, Wijmenga, Cisca, Wilson, David C., Westra, Harm-Jan, Xavier, Ramnik J., Zhao, Zhen Z., Ponsioen, Cyriel Y., Andersen, Vibeke, Torkvist, Leif, Gazouli, Maria, Anagnou, Nicholas P., Karlsen, Tom H., Kupcinskas, Limas, Sventoraityte, Jurgita, Mansfield, John C., Kugathasan, Subra, Silverberg, Mark S., Halfvarson, Jonas, Rotter, Jerome I., Mathew, Christopher G., Griffiths, Anne M., Gearry, Richard, Ahmad, Tariq, Brant, Steven R., Chamaillard, Mathias, Satsangi, Jack, Cho, Judy H., Schreiber, Stefan, Daly, Mark J., Barrett, Jeffrey C., Parkes, Miles, Annese, Vito, Hakonarson, Hakon, Radford-Smith, Graham, Duerr, Richard H., Vermeire, Séverine, Weersma, Rinse K., Rioux, John D.
Publicado 2011