Public health risks from subclinical variant CJD

por Diack, Abigail B., Will, Robert G., Manson, Jean C.
Publicado 2017

Increased susceptibility of transgenic mice expressing human PrP to experimental sheep bovine spongiform encephalopathy is not due to increased agent titre in sheep brain tissue

por Plinston, Chris, Hart, Patricia, Hunter, Nora, Manson, Jean C., Barron, Rona M.
Publicado 2014

Oral Prion Neuroinvasion Occurs Independently of PrP(C) Expression in the Gut Epithelium

por Marshall, Alison, Bradford, Barry M., Clarke, Alan R., Manson, Jean C., Mabbott, Neil A.
Publicado 2018

Insights into Mechanisms of Chronic Neurodegeneration

por Diack, Abigail B., Alibhai, James D., Barron, Rona, Bradford, Barry, Piccardo, Pedro, Manson, Jean C.
Publicado 2016

Analysis of gene expression in the nervous system identifies key genes and novel candidates for health and disease

por Carpanini, Sarah M, Wishart, Thomas M, Gillingwater, Thomas H, Manson, Jean C, Summers, Kim M
Publicado 2017

Cellular Prion Protein Expression Is Not Regulated by the Alzheimer's Amyloid Precursor Protein Intracellular Domain

por Lewis, Victoria, Whitehouse, Isobel J., Baybutt, Herbert, Manson, Jean C., Collins, Steven J., Hooper, Nigel M.
Publicado 2012

Prion infectivity in the spleen of a PRNP heterozygous individual with subclinical variant Creutzfeldt–Jakob disease

por Bishop, Matthew T., Diack, Abigail B., Ritchie, Diane L., Ironside, James W., Will, Robert G., Manson, Jean C.
Publicado 2013

Variant Creutzfeldt-Jakob disease strain is identical in individuals of two PRNP codon 129 genotypes

por Diack, Abigail B, Boyle, Aileen, Plinston, Christopher, Hunt, Emma, Bishop, Matthew T, Will, Robert G, Manson, Jean C
Publicado 2019

No Adaptation of the Prion Strain in a Heterozygous Case of Variant Creutzfeldt-Jakob Disease

por Boyle, Aileen, Plinston, Chris, Laing, Fraser, Mackenzie, Graeme, Will, Robert G., Manson, Jean C., Diack, Abigail B.
Publicado 2020

Spermine increases acetylation of tubulins and facilitates autophagic degradation of prion aggregates

por Phadwal, Kanchan, Kurian, Dominic, Salamat, Muhammad Khalid F., MacRae, Vicky E., Diack, Abigail B., Manson, Jean C.
Publicado 2018

Defining the Microglia Response during the Time Course of Chronic Neurodegeneration

por Vincenti, James E., Murphy, Lita, Grabert, Kathleen, McColl, Barry W., Cancellotti, Enrico, Freeman, Tom C., Manson, Jean C.
Publicado 2016

No Major Change in vCJD Agent Strain after Secondary Transmission via Blood Transfusion

por Bishop, Matthew T., Ritchie, Diane L., Will, Robert G., Ironside, James W., Head, Mark W., Thomson, Val, Bruce, Moira, Manson, Jean C.
Publicado 2008

A polymorphism in the regulatory region of PRNP is associated with increased risk of sporadic Creutzfeldt-Jakob disease

por Sanchez-Juan, Pascual, Bishop , Matthew T, Croes , Esther A, Knight , Richard SG, Will , Robert G, van Duijn , Cornelia M, Manson , Jean C
Publicado 2011

Follicular Dendritic Cell-Specific Prion Protein (PrP(c)) Expression Alone Is Sufficient to Sustain Prion Infection in the Spleen

por McCulloch, Laura, Brown, Karen L., Bradford, Barry M., Hopkins, John, Bailey, Mick, Rajewsky, Klaus, Manson, Jean C., Mabbott, Neil A.
Publicado 2011

Variant CJD: 18 years of research and surveillance

por Diack, Abigail B, Head, Mark W, McCutcheon, Sandra, Boyle, Aileen, Knight, Richard, Ironside, James W, Manson, Jean C, Will, Robert G
Publicado 2014

Distribution of Misfolded Prion Protein Seeding Activity Alone Does Not Predict Regions of Neurodegeneration

por Alibhai, James, Blanco, Richard A., Barria, Marcelo A., Piccardo, Pedro, Caughey, Byron, Perry, V. Hugh, Freeman, Tom C., Manson, Jean C.
Publicado 2016

The Glycosylation Status of PrP(C) Is a Key Factor in Determining Transmissible Spongiform Encephalopathy Transmission between Species

por Wiseman, Frances K., Cancellotti, Enrico, Piccardo, Pedro, Iremonger, Kayleigh, Boyle, Aileen, Brown, Deborah, Ironside, James W., Manson, Jean C., Diack, Abigail B.
Publicado 2015

Ablation of Prion Protein in Wild Type Human Amyloid Precursor Protein (APP) Transgenic Mice Does Not Alter The Proteolysis of APP, Levels of Amyloid-β or Pathologic Phenotype

por Whitehouse, Isobel J., Brown, Deborah, Baybutt, Herbert, Diack, Abigail B., Kellett, Katherine A. B., Piccardo, Pedro, Manson, Jean C., Hooper, Nigel M.
Publicado 2016

Similarities of Variant Creutzfeldt-Jakob Disease Strain in Mother and Son in Spain to UK Reference Case

por Diack, Abigail B., Boyle, Aileen, Ritchie, Diane, Plinston, Chris, Kisielewski, Dorothy, de Pedro-Cuesta, Jesús, Rábano, Alberto, Will, Robert G., Manson, Jean C.
Publicado 2017

Development of a sensitive real-time quaking-induced conversion (RT-QuIC) assay for application in prion-infected blood

por Thomas, Charlotte M., Salamat, M. Khalid F., de Wolf, Christopher, McCutcheon, Sandra, Blanco, A. Richard Alejo, Manson, Jean C., Hunter, Nora, Houston, E. Fiona
Publicado 2023