ATP directed agent, 8-chloro-adenosine, induces AMP activated protein kinase activity, leading to autophagic cell death in breast cancer cells

por Stellrecht, Christine M, Vangapandu, Hima V, Le, Xiao-Feng, Mao, Weiqun, Shentu, Shujun
Publicado 2014

Amino Acid Deprivation-Induced Autophagy Requires Upregulation of DIRAS3 through Reduction of E2F1 and E2F4 Transcriptional Repression

por Sutton, Margie N., Huang, Gilbert Y., Zhou, Jinhua, Mao, Weiqun, Langley, Robert, Lu, Zhen, Bast, Robert C.
Publicado 2019

A Novel Salt Inducible Kinase 2 Inhibitor, ARN-3261, Sensitizes Ovarian Cancer Cell Lines and Xenografts to Carboplatin

por Fan, Dengxuan, Yang, Hailing, Mao, Weiqun, Rask, Philip J., Pang, Lan, Xu, Congjian, Vankayalapat, Hariprasad, Ahmed, Ahmed A., Bast, Robert C., Lu, Zhen
Publicado 2021

Modulation of MicroRNA-194 and Cell Migration by HER2-Targeting Trastuzumab in Breast Cancer

por Le, Xiao-Feng, Almeida, Maria I., Mao, Weiqun, Spizzo, Riccardo, Rossi, Simona, Nicoloso, Milena S., Zhang, Shu, Wu, Yun, Calin, George A., Bast, Robert C.
Publicado 2012

NDN is an imprinted tumor suppressor gene that is downregulated in ovarian cancers through genetic and epigenetic mechanisms

por Yang, Hailing, Das, Partha, Yu, Yinhua, Mao, Weiqun, Wang, Yan, Baggerly, Keith, Wang, Ying, Marquez, Rebecca T., Bedi, Anuja, Liu, Jinsong, Fishman, David, Lu, Zhen, Bast, Robert C.
Publicado 2015

Membrane anchoring of the DIRAS3 N-terminal extension permits tumor suppressor function

por Liang, Xiaowen, Jung, Sung Yun, Fong, Lon Wolf, Bildik, Gamze, Gray, Joshua P., Mao, Weiqun, Zhang, Shuxing, Millward, Steven W., Gorfe, Alemayehu A., Zhou, Yong, Lu, Zhen, Bast, Robert C.
Publicado 2023

Induction of autophagy by ARHI (DIRAS3) alters fundamental metabolic pathways in ovarian cancer models

por Ornelas, Argentina, McCullough, Christopher R., Lu, Zhen, Zacharias, Niki M., Kelderhouse, Lindsay E., Gray, Joshua, Yang, Hailing, Engel, Brian J., Wang, Yan, Mao, Weiqun, Sutton, Margie N., Bhattacharya, Pratip K., Bast, Robert C., Millward, Steven W.
Publicado 2016

DIRAS3-Derived Peptide Inhibits Autophagy in Ovarian Cancer Cells by Binding to Beclin1

por Sutton, Margie N., Huang, Gilbert Y., Liang, Xiaowen, Sharma, Rajesh, Reger, Albert S., Mao, Weiqun, Pang, Lan, Rask, Philip J., Lee, Kwangkook, Gray, Joshua P., Hurwitz, Amy M., Palzkill, Timothy, Millward, Steven W., Kim, Choel, Lu, Zhen, Bast, Robert C.
Publicado 2019

CDK5 Regulates Paclitaxel Sensitivity in Ovarian Cancer Cells by Modulating AKT Activation, p21Cip1- and p27Kip1-Mediated G1 Cell Cycle Arrest and Apoptosis

por Zhang, Shu, Lu, Zhen, Mao, Weiqun, Ahmed, Ahmed A., Yang, Hailing, Zhou, Jinhua, Jennings, Nicholas, Rodriguez-Aguayo, Cristian, Lopez-Berestein, Gabriel, Miranda, Roberto, Qiao, Wei, Baladandayuthapani, Veera, Li, Zongfang, Sood, Anil K., Liu, Jinsong, Le, Xiao-Feng, Bast, Robert C.
Publicado 2015

SIK2 inhibition enhances PARP inhibitor activity synergistically in ovarian and triple-negative breast cancers

por Lu, Zhen, Mao, Weiqun, Yang, Hailing, Santiago-O’Farrill, Janice M., Rask, Philip J., Mondal, Jayanta, Chen, Hu, Ivan, Cristina, Liu, Xiuping, Liu, Chang-Gong, Xi, Yuanxin, Masuda, Kenta, Carrami, Eli M., Chen, Meng, Tang, Yitao, Pang, Lan, Lakomy, David S., Calin, George A., Liang, Han, Ahmed, Ahmed A., Vankayalapati, Hariprasad, Bast, Robert C.
Publicado 2022