GATA2 deficiency and MDS/AML: Experimental strategies for disease modelling and future therapeutic prospects

por Kotmayer, Lili, Romero‐Moya, Damia, Marin‐Bejar, Oskar, Kozyra, Emilia, Català, Albert, Bigas, Anna, Wlodarski, Marcin W., Bödör, Csaba, Giorgetti, Alessandra
Publicado 2022

Genome-wide analysis of the human p53 transcriptional network unveils a lncRNA tumour suppressor signature

por Sánchez, Yolanda, Segura, Victor, Marín-Béjar, Oskar, Athie, Alejandro, Marchese, Francesco P., González, Jovanna, Bujanda, Luis, Guo, Shuling, Matheu, Ander, Huarte, Maite
Publicado 2014

P698: CRISPR/CAS9 GENE EDITING IN HEMATOPOIETIC STEM CELLS TO MODEL CLONAL COMPETITION IN VIVO AND IN VITRO FOR GATA2 DEFICIENCY

por Romero-Moya, Damia, Marin-Bejar, Oskar, Distefano, Maximiliano, Pera, Joan, Castaño, Julio, Gonzalez, Jessica, Kotmayer, Lili, Bödör, Csaba, Català, Albert, W Wlodarski, Marcin, Bigas, Anna, Giorgetti, Alessandra
Publicado 2023

The human lncRNA LINC-PINT inhibits tumor cell invasion through a highly conserved sequence element

por Marín-Béjar, Oskar, Mas, Aina M., González, Jovanna, Martinez, Dannys, Athie, Alejandro, Morales, Xabier, Galduroz, Mikel, Raimondi, Ivan, Grossi, Elena, Guo, Shuling, Rouzaut, Ana, Ulitsky, Igor, Huarte, Maite
Publicado 2017

Dynamic reversal of random X-Chromosome inactivation during iPSC reprogramming

por Janiszewski, Adrian, Talon, Irene, Chappell, Joel, Collombet, Samuel, Song, Juan, De Geest, Natalie, To, San Kit, Bervoets, Greet, Marin-Bejar, Oskar, Provenzano, Caterina, Vanheer, Lotte, Marine, Jean-Christophe, Rambow, Florian, Pasque, Vincent
Publicado 2019

Pint lincRNA connects the p53 pathway with epigenetic silencing by the Polycomb repressive complex 2

por Marín-Béjar, Oskar, Marchese, Francesco P, Athie, Alejandro, Sánchez, Yolanda, González, Jovanna, Segura, Victor, Huang, Lulu, Moreno, Isabel, Navarro, Alfons, Monzó, Mariano, García-Foncillas, Jesús, Rinn, John L, Guo, Shuling, Huarte, Maite
Publicado 2013

CRISPR screens identify tumor‐promoting genes conferring melanoma cell plasticity and resistance

por Gautron, Arthur, Bachelot, Laura, Aubry, Marc, Leclerc, Delphine, Quéméner, Anaïs M, Corre, Sébastien, Rambow, Florian, Paris, Anaïs, Tardif, Nina, Leclair, Héloïse M, Marin‐Bejar, Oskar, Coulouarn, Cédric, Marine, Jean‐Christophe, Galibert, Marie‐Dominique, Gilot, David
Publicado 2021

Analysis of copy number alterations reveals the lncRNA ALAL-1 as a regulator of lung cancer immune evasion

por Athie, Alejandro, Marchese, Francesco P., González, Jovanna, Lozano, Teresa, Raimondi, Ivan, Juvvuna, Prasanna Kumar, Abad, Amaya, Marin-Bejar, Oskar, Serizay, Jacques, Martínez, Dannys, Ajona, Daniel, Pajares, Maria Jose, Sandoval, Juan, Montuenga, Luis M., Kanduri, Chandrasekhar, Lasarte, Juan J., Huarte, Maite
Publicado 2020

Blockade of the pro‐fibrotic reaction mediated by the miR‐143/‐145 cluster enhances the responses to targeted therapy in melanoma

por Diazzi, Serena, Baeri, Alberto, Fassy, Julien, Lecacheur, Margaux, Marin‐Bejar, Oskar, Girard, Christophe A, Lefevre, Lauren, Lacoux, Caroline, Irondelle, Marie, Mounier, Carine, Truchi, Marin, Couralet, Marie, Ohanna, Mickael, Carminati, Alexandrine, Berestjuk, Ilona, Larbret, Frederic, Gilot, David, Vassaux, Georges, Marine, Jean‐Christophe, Deckert, Marcel, Mari, Bernard, Tartare‐Deckert, Sophie
Publicado 2022

P718: EPIGENOME PROFILING REVEALS ABERRANT DNA METHYLATION SIGNATURE IN GATA2 DEFICIENCY

por Marin-Bejar, Oskar, Romero-Moya, Damia, Rodriguez-Ubreva, Javier, Distefano, Maximiliano, Lessi, Francesca, Aretini, Paolo, Liquori, Alessandro, Castaño, Julio, Kozyra, Emilia, Kotmayer, Lili, Bueno, Clara, Cervera, José, Carlos Rodriguez-Gallego, José, F Nomdedeu, Josep, Murillo-Sanjuán, Laura, Díaz de Heredia, Cristina, Pérez-Martinez, Antonio, López-Cardenas, Félix, Martínez-Laperche, Carolina, Dorado-Herrero, Nieves, M Marco, Francisco, Prósper, Felipe, Menendez, Pablo, Valcárcel, David, Ballestar, Esteban, Bödör, Csaba, Bigas, Anna, Catalá, Albert, W Wlodarski, Marcin, Giorgetti, Alessandra
Publicado 2023

Epigenome profiling reveals aberrant DNA methylation signature in GATA2 deficiency

por Marin-Bejar, Oskar, Romero-Moya, Damia, Rodriguez-Ubreva, Javier, Distefano, Maximiliano, Lessi, Francesca, Aretini, Paolo, Liquori, Alessandro, Castaño, Julio, Kozyra, Emilia, Kotmayer, Lili, Bueno, Clara, Cervera, José, Rodriguez-Gallego, José Carlos, Nomdedeu, Josep F., Murillo-Sanjuán, Laura, de Heredia, Cristina Díaz, Pérez-Martinez, Antonio, López-Cadenas, Félix, Martínez-Laperche, Carolina, Dorado-Herrero, Nieves, Marco, Francisco M., Prósper, Felipe, Menendez, Pablo, Valcárcel, David, Ballestar, Esteban, Bödör, Csaba, Bigas, Anna, Catalá, Albert, Wlodarski, Marcin W., Giorgetti, Alessandra
Publicado 2023

A palmitate-rich metastatic niche enables metastasis growth via p65 acetylation resulting in pro-metastatic NF-κB signaling

por Altea-Manzano, Patricia, Doglioni, Ginevra, Liu, Yawen, Cuadros, Alejandro M., Nolan, Emma, Fernández-García, Juan, Wu, Qi, Planque, Mélanie, Laue, Kathrin Julia, Cidre-Aranaz, Florencia, Liu, Xiao-Zheng, Marin-Bejar, Oskar, Van Elsen, Joke, Vermeire, Ines, Broekaert, Dorien, Demeyer, Sofie, Spotbeen, Xander, Idkowiak, Jakub, Montagne, Aurelie, Demicco, Margherita, Alkan, H Furkan, Rabas, Nick, Riera-Domingo, Carla, Richard, François, Geukens, Tatjana, De Schepper, Maxim, Leduc, Sophia, Hatse, Sigrid, Lambrechts, Yentl, Kay, Emily Jane, Lilla, Sergio, Alekseenko, Alisa, Geldhof, Vincent, Boeckx, Bram, de la Calle Arregui, Celia, Floris, Giuseppe, Swinnen, Johannes V., Marine, Jean-Christophe, Lambrechts, Diether, Pelechano, Vicent, Mazzone, Massimiliano, Zanivan, Sara, Cools, Jan, Wildiers, Hans, Baud, Véronique, Grünewald, Thomas G.P., Ben-David, Uri, Desmedt, Christine, Malanchi, Ilaria, Fendt, Sarah-Maria
Publicado 2023