Identification of selective inhibitors of RET and comparison with current clinical candidates through development and validation of a robust screening cascade

por Watson, Amanda J., Hopkins, Gemma V., Hitchin, Samantha, Begum, Habiba, Jones, Stuart, Jordan, Allan, Holt, Sarah, March, H. Nikki, Newton, Rebecca, Small, Helen, Stowell, Alex, Waddell, Ian D., Waszkowycz, Bohdan, Ogilvie, Donald J.
Publicado 2016

Anilinoquinazoline inhibitors of the RET kinase domain—Elaboration of the 7-position

por Jordan, Allan M., Begum, Habiba, Fairweather, Emma, Fritzl, Samantha, Goldberg, Kristin, Hopkins, Gemma V., Hamilton, Niall M., Lyons, Amanda J., March, H. Nikki, Newton, Rebecca, Small, Helen F., Vishwanath, Swamy, Waddell, Ian D., Waszkowycz, Bohdan, Watson, Amanda J., Ogilvie, Donald J.
Publicado 2016

Insertional mutagenesis identifies multiple networks of co-operating genes driving intestinal tumorigenesis

por March, H. Nikki, Rust, Alistair G., Wright, Nicholas A., Hoeve, Jelle ten, de Ridder, Jeroen, Eldridge, Matthew, van der Weyden, Louise, Berns, Anton, Gadiot, Jules, Uren, Anthony, Kemp, Richard, Arends, Mark J., Wessels, Lodewyk F. A., Winton, Douglas J., Adams, David J.
Publicado 2011

Nuclear receptor binding protein 1 regulates intestinal progenitor cell homeostasis and tumour formation

por Wilson, Catherine H, Crombie, Catriona, van der Weyden, Louise, Poulogiannis, George, Rust, Alistair G, Pardo, Mercedes, Gracia, Tannia, Yu, Lu, Choudhary, Jyoti, Poulin, Gino B, McIntyre, Rebecca E, Winton, Douglas J, March, H Nikki, Arends, Mark J, Fraser, Andrew G, Adams, David J
Publicado 2012