Ap4b1-knockout mouse model of hereditary spastic paraplegia type 47 displays motor dysfunction, aberrant brain morphology and ATG9A mislocalization

por Scarrott, Joseph M, Alves-Cruzeiro, João, Marchi, Paolo M, Webster, Christopher P, Yang, Zih-Liang, Karyka, Evangelia, Marroccella, Raffaele, Coldicott, Ian, Thomas, Hannah, Azzouz, Mimoun
Publicado 2023

Randomised phase 3 open-label trial of first-line treatment with gemcitabine in association with docetaxel or paclitaxel in women with metastatic breast cancer: a comparison of dif...

por Del Mastro, Lucia, Fabi, Alessandra, Mansutti, Mauro, De Laurentiis, Michele, Durando, Antonio, Merlo, Domenico Franco, Bruzzi, Paolo, La Torre, Ignazia, Ceccarelli, Matteo, Kazeem, Gbenga, Marchi, Paolo, Boy, Davide, Venturini, Marco, De Placido, Sabino, Cognetti, Francesco
Publicado 2013

SPG15 protein deficits are at the crossroads between lysosomal abnormalities, altered lipid metabolism and synaptic dysfunction

por Marrone, Lara, Marchi, Paolo M, Webster, Christopher P, Marroccella, Raffaele, Coldicott, Ian, Reynolds, Steven, Alves-Cruzeiro, João, Yang, Zih-Liang, Higginbottom, Adrian, Khundadze, Mukhran, Shaw, Pamela J, Hübner, Christian A, Livesey, Matthew R, Azzouz, Mimoun
Publicado 2022

SMN-deficient cells exhibit increased ribosomal DNA damage

por Karyka, Evangelia, Berrueta Ramirez, Nelly, Webster, Christopher P, Marchi, Paolo M, Graves, Emily J, Godena, Vinay K, Marrone, Lara, Bhargava, Anushka, Ray, Swagat, Ning, Ke, Crane, Hannah, Hautbergue, Guillaume M, El-Khamisy, Sherif F, Azzouz, Mimoun
Publicado 2022

C9ORF72-derived poly-GA DPRs undergo endocytic uptake in iAstrocytes and spread to motor neurons

por Marchi, Paolo M, Marrone, Lara, Brasseur, Laurent, Coens, Audrey, Webster, Christopher P, Bousset, Luc, Destro, Marco, Smith, Emma F, Walther, Christa G, Alfred, Victor, Marroccella, Raffaele, Graves, Emily J, Robinson, Darren, Shaw, Allan C, Wan, Lai Mei, Grierson, Andrew J, Ebbens, Stephen J, De Vos, Kurt J, Hautbergue, Guillaume M, Ferraiuolo, Laura, Melki, Ronald, Azzouz, Mimoun
Publicado 2022