A Neuroprotective Locus Modulates Ischemic Stroke Infarction Independent of Collateral Vessel Anatomy

por Lee, Han Kyu, Wetzel-Strong, Sarah E., Aylor, David L., Marchuk, Douglas A.
Publicado 2021

EndoU is a novel regulator of AICD during peripheral B cell selection

por Poe, Jonathan C., Kountikov, Evgueni I., Lykken, Jacquelyn M., Natarajan, Abirami, Marchuk, Douglas A., Tedder, Thomas F.
Publicado 2014

ALK1 signalling analysis identifies angiogenesis related genes and reveals disparity between TGF-β and constitutively active receptor induced gene expression

por Lux, Andreas, Salway, Fiona, Dressman, Holly K, Kröner-Lux, Gabriele, Hafner, Mathias, Day, Philip JR, Marchuk, Douglas A, Garland, John
Publicado 2006

Single-nucleus DNA sequencing reveals hidden somatic loss-of-heterozygosity in Cerebral Cavernous Malformations

por Ressler, Andrew K., Snellings, Daniel A., Girard, Romuald, Gallione, Carol J., Lightle, Rhonda, Allen, Andrew S., Awad, Issam A., Marchuk, Douglas A.
Publicado 2023

Tnni3k Modifies Disease Progression in Murine Models of Cardiomyopathy

por Wheeler, Ferrin C., Tang, Hao, Marks, Odessa A., Hadnott, Tracy N., Chu, Pei-Lun, Mao, Lan, Rockman, Howard A., Marchuk, Douglas A.
Publicado 2009

Natural Genetic Variation of Integrin Alpha L (Itgal) Modulates Ischemic Brain Injury in Stroke

por Keum, Sehoon, Lee, Han Kyu, Chu, Pei-Lun, Kan, Matthew J., Huang, Min-Nung, Gallione, Carol J., Gunn, Michael D., Lo, Donald C., Marchuk, Douglas A.
Publicado 2013

Developmental venous anomalies are a genetic primer for cerebral cavernous malformations

por Snellings, Daniel A., Girard, Romuald, Lightle, Rhonda, Srinath, Abhinav, Romanos, Sharbel, Li, Ying, Chen, Chang, Ren, Aileen A., Kahn, Mark L., Awad, Issam A., Marchuk, Douglas A.
Publicado 2022

Pilot investigation of circulating angiogenic and inflammatory biomarkers associated with vascular malformations

por Wetzel-Strong, Sarah E., Weinsheimer, Shantel, Nelson, Jeffrey, Pawlikowska, Ludmila, Clark, Dewi, Starr, Mark D., Liu, Yingmiao, Kim, Helen, Faughnan, Marie E., Nixon, Andrew B., Marchuk, Douglas A.
Publicado 2021

Dissection of a Quantitative Trait Locus for PR Interval Duration Identifies Tnni3k as a Novel Modulator of Cardiac Conduction

por Lodder, Elisabeth M., Scicluna, Brendon P., Milano, Annalisa, Sun, Albert Y., Tang, Hao, Remme, Carol Ann, Moerland, Perry D., Tanck, Michael W. T., Pitt, Geoffrey S., Marchuk, Douglas A., Bezzina, Connie R.
Publicado 2012

Propranolol as therapy for cerebral cavernous malformations: a cautionary note

por Shenkar, Robert, Moore, Thomas, Benavides, Christian, Lightle, Rhonda, Detter, Matthew R., Hobson, Nicholas, Girard, Romuald, DeBiasse, Dorothy, Patrucco, Mary, Gallione, Carol, Zabramski, Joseph M., Marchuk, Douglas A., Awad, Issam A.
Publicado 2022

The Cerebral Cavernous Malformation signaling pathway promotes vascular integrity via Rho GTPases

por Whitehead, Kevin J., Chan, Aubrey C., Navankasattusas, Sutip, Koh, Wonshill, London, Nyall R., Ling, Jing, Mayo, Anne H., Drakos, Stavros G., Jones, Christopher A., Zhu, Weiquan, Marchuk, Douglas A., Davis, George A., Li, Dean Y.
Publicado 2009

Two Genes on A/J Chromosome 18 Are Associated with Susceptibility to Staphylococcus aureus Infection by Combined Microarray and QTL Analyses

por Ahn, Sun-Hee, Deshmukh, Hitesh, Johnson, Nicole, Cowell, Lindsay G., Rude, Thomas H., Scott, William K., Nelson, Charlotte L., Zaas, Aimee K., Marchuk, Douglas A., Keum, Sehoon, Lamlertthon, Supaporn, Sharma-Kuinkel, Batu K., Sempowski, Gregory D., Fowler, Vance G.
Publicado 2010

EXCEPTIONAL AGGRESSIVENESS OF CEREBRAL CAVERNOUS MALFORMATION DISEASE ASSOCIATED WITH PDCD10 MUTATIONS

por Shenkar, Robert, Shi, Changbin, Rebeiz, Tania, Stockton, Rebecca A., McDonald, David A., Mikati, Abdul Ghani, Zhang, Lingjiao, Austin, Cecilia, Akers, Amy L., Gallione, Carol J., Rorrer, Autumn, Gunel, Murat, Min, Wang, De Souza, Jorge Marcondes, Lee, Connie, Marchuk, Douglas A., Awad, Issam A.
Publicado 2014

Phenotypic Characterization of Murine Models of Cerebral Cavernous Malformations

por Zeineddine, Hussein A., Girard, Romuald, Saadat, Laleh, Shen, Le, Lightle, Rhonda, Moore, Thomas, Cao, Ying, Hobson, Nick, Shenkar, Robert, Avner, Kenneth, Chaudager, Kiranj, Koskimäki, Janne, Polster, Sean P., Fam, Maged D., Shi, Changbin, Lopez-Ramirez, Miguel Alejandro, Tang, Alan T., Gallione, Carol, Kahn, Mark L., Ginsberg, Mark, Marchuk, Douglas A., Awad, Issam A.
Publicado 2018

Transcriptome clarifies mechanisms of lesion genesis versus progression in models of Ccm3 cerebral cavernous malformations

por Koskimäki, Janne, Zhang, Dongdong, Li, Yan, Saadat, Laleh, Moore, Thomas, Lightle, Rhonda, Polster, Sean P., Carrión-Penagos, Julián, Lyne, Seán B., Zeineddine, Hussein A., Shi, Changbin, Shenkar, Robert, Romanos, Sharbel, Avner, Kenneth, Srinath, Abhinav, Shen, Le, Detter, Matthew R., Snellings, Daniel, Cao, Ying, Lopez-Ramirez, Miguel A., Fonseca, Gregory, Tang, Alan T., Faber, Pieter, Andrade, Jorge, Ginsberg, Mark, Kahn, Mark L., Marchuk, Douglas A., Girard, Romuald, Awad, Issam A.
Publicado 2019

Cerebral cavernous malformations are driven by ADAMTS5 proteolysis of versican

por Hong, Courtney C., Tang, Alan T., Detter, Matthew R., Choi, Jaesung P., Wang, Rui, Yang, Xi, Guerrero, Andrea A., Wittig, Carl F., Hobson, Nicholas, Girard, Romuald, Lightle, Rhonda, Moore, Thomas, Shenkar, Robert, Polster, Sean P., Goddard, Lauren M., Ren, Aileen A., Leu, N. Adrian, Sterling, Stephanie, Yang, Jisheng, Li, Li, Chen, Mei, Mericko-Ishizuka, Patricia, Dow, Lukas E., Watanabe, Hideto, Schwaninger, Markus, Min, Wang, Marchuk, Douglas A., Zheng, Xiangjian, Awad, Issam A., Kahn, Mark L.
Publicado 2020