Structures of PGAM5 Provide Insight into Active Site Plasticity and Multimeric Assembly

por Chaikuad, Apirat, Filippakopoulos, Panagis, Marcsisin, Sean R., Picaud, Sarah, Schröder, Martin, Sekine, Shiori, Ichijo, Hidenori, Engen, John R., Takeda, Kohsuke, Knapp, Stefan
Publicado 2017

Long-Term Prophylaxis and Pharmacokinetic Evaluation of Intramuscular Nano- and Microparticle Decoquinate in Mice Infected with P. berghei Sporozoites

por Li, Qigui, Xie, Lisa, Caridha, Diana, Zeng, Qiang, Zhang, Jing, Roncal, Norma, Zhang, Ping, Vuong, Chau, Potter, Brittney, Sousa, Jason, Marcsisin, Sean, Read, Lisa, Hickman, Mark
Publicado 2017

CYP450 phenotyping and metabolite identification of quinine by accurate mass UPLC-MS analysis: a possible metabolic link to blackwater fever

por Marcsisin, Sean R, Jin, Xiannu, Bettger, Theresa, McCulley, Nicholas, Sousa, Jason C, Shanks, G Dennis, Tekwani, Babu L, Sahu, Rajnish, Reichard, Gregory A, Sciotti, Richard J, Melendez, Victor, Pybus, Brandon S
Publicado 2013

The metabolism of primaquine to its active metabolite is dependent on CYP 2D6

por Pybus, Brandon S, Marcsisin, Sean R, Jin, Xiannu, Deye, Gregory, Sousa, Jason C, Li, Qigui, Caridha, Diana, Zeng, Qiang, Reichard, Gregory A, Ockenhouse, Christian, Bennett, Jason, Walker, Larry A, Ohrt, Colin, Melendez, Victor
Publicado 2013

Cytochrome P450 2D-mediated metabolism is not necessary for tafenoquine and primaquine to eradicate the erythrocytic stages of Plasmodium berghei

por Milner, Erin E., Berman, Jonathan, Caridha, Diana, Dickson, Samuel P., Hickman, Mark, Lee, Patricia J., Marcsisin, Sean R., Read, Lisa T., Roncal, Norma, Vesely, Brian A., Xie, Lisa H., Zhang, Jing, Zhang, Ping, Li, Qigui
Publicado 2016

Differential kinetic profiles and metabolism of primaquine enantiomers by human hepatocytes

por Fasinu, Pius S., Avula, Bharathi, Tekwani, Babu L., Nanayakkara, N. P. Dhammika, Wang, Yan-Hong, Bandara Herath, H. M. T., McChesney, James D., Reichard, Gregory A., Marcsisin, Sean R., Elsohly, Mahmoud A., Khan, Shabana I., Khan, Ikhlas A., Walker, Larry A.
Publicado 2016

Pre-clinical evaluation of CYP 2D6 dependent drug–drug interactions between primaquine and SSRI/SNRI antidepressants

por Jin, Xiannu, Potter, Brittney, Luong, Thu-lan, Nelson, Jennifer, Vuong, Chau, Potter, Corttney, Xie, Lisa, Zhang, Jing, Zhang, Ping, Sousa, Jason, Li, Qigui, Pybus, Brandon S., Kreishman-Deitrick, Mara, Hickman, Mark, Smith, Philip L., Paris, Robert, Reichard, Gregory, Marcsisin, Sean R.
Publicado 2016

Enantioselective metabolism of primaquine by human CYP2D6

por Fasinu, Pius S, Tekwani, Babu L, Nanayakkara, NP Dhammika, Avula, Bharathi, Herath, HMT Bandara, Wang, Yan-Hong, Adelli, Vijender R, Elsohly, Mahmoud A, Khan, Shabana I, Khan, Ikhlas A, Pybus, Brandon S, Marcsisin, Sean R, Reichard, Gregory A, McChesney, James D, Walker, Larry A
Publicado 2014

Tafenoquine and NPC-1161B require CYP 2D metabolism for anti-malarial activity: implications for the 8-aminoquinoline class of anti-malarial compounds

por Marcsisin, Sean R, Sousa, Jason C, Reichard, Gregory A, Caridha, Diana, Zeng, Qiang, Roncal, Norma, McNulty, Ronan, Careagabarja, Julio, Sciotti, Richard J, Bennett, Jason W, Zottig, Victor E, Deye, Gregory, Li, Qigui, Read, Lisa, Hickman, Mark, Nanayakkara, N P Dhammika, Walker, Larry A, Smith, Bryan, Melendez, Victor, Pybus, Brandon S
Publicado 2014

Corrigendum to: Determination of Cytochrome P450 Isoenzyme 2D6 (CYP2D6) Genotypes and Pharmacogenomic Impact on Primaquine Metabolism in an Active-Duty US Military Population

por Spring, Michele D, Sousa, Jason C, Li, Qigui, Darko, Christian A, Morrison, Meshell N, Marcsisin, Sean R, Mills, Kristin T, Potter, Brittney M, Paolino, Kristopher M, Twomey, Patrick S, Moon, James E, Tosh, Donna M, Cicatelli, Susan B, Froude, Jeffrey W, Pybus, Brandon S, Oliver, Thomas G, Mccarthy, William F, Waters, Norman C, Smith, Philip L, Reichard, Gregory A, Bennett, Jason W
Publicado 2020

Determination of Cytochrome P450 Isoenzyme 2D6 (CYP2D6) Genotypes and Pharmacogenomic Impact on Primaquine Metabolism in an Active-Duty US Military Population

por Spring, Michele D, Sousa, Jason C, Li, Qigui, Darko, Christian A, Morrison, Meshell N, Marcsisin, Sean R, Mills, Kristin T, Potter, Brittney M, Paolino, Kristopher M, Twomey, Patrick S, Moon, James E, Tosh, Donna M, Cicatelli, Susan B, Froude, Jeffrey W, Pybus, Brandon S, Oliver, Thomas G, McCarthy, William F, Waters, Norman C, Smith, Philip L, Reichard, Gregory A, Bennett, Jason W
Publicado 2019