LKB1 tumor suppressor: Therapeutic opportunities knock when LKB1 is inactivated

por Zhou, Wei, Zhang, Jun, Marcus, Adam I.
Publicado 2014

Dysregulation of mTOR activity through LKB1 inactivation

por Zhou, Wei, Marcus, Adam I., Vertino, Paula M.
Publicado 2013

RhoA, a novel tumor suppressor or oncogene as a therapeutic target?()

por Gilbert-Ross, Melissa, Marcus, Adam I., Zhou, Wei
Publicado 2014

The complex ecosystem in non small cell lung cancer invasion

por Haney, Seth, Konen, Jessica, Marcus, Adam I., Bazhenov, Maxim
Publicado 2018

Vimentin regulates lung cancer cell adhesion through a VAV2-Rac1 pathway to control focal adhesion kinase activity

por Havel, Lauren S., Kline, Erik R., Salgueiro, Alessandra M., Marcus, Adam I.
Publicado 2014

Local alignment vectors reveal cancer cell-induced ECM fiber remodeling dynamics

por Lee, Byoungkoo, Konen, Jessica, Wilkinson, Scott, Marcus, Adam I., Jiang, Yi
Publicado 2017

Amine-Reactive Fluorene Probes: Synthesis, Optical Characterization, Bioconjugation, and Two-Photon Fluorescence Imaging

por Morales, Alma R., Schafer-Hales, Katherine J., Marcus, Adam I., Belfield, Kevin D.
Publicado 2008

TASI: A software tool for spatial-temporal quantification of tumor spheroid dynamics

por Hou, Yue, Konen, Jessica, Brat, Daniel J., Marcus, Adam I., Cooper, Lee A. D.
Publicado 2018

LKB1 kinase-dependent and -independent defects disrupt polarity and adhesion signaling to drive collagen remodeling during invasion

por Konen, Jessica, Wilkinson, Scott, Lee, Byoungkoo, Fu, Haian, Zhou, Wei, Jiang, Yi, Marcus, Adam I.
Publicado 2016

Withania somnifera Root Extract Inhibits Mammary Cancer Metastasis and Epithelial to Mesenchymal Transition

por Yang, Zhen, Garcia, Anapatricia, Xu, Songli, Powell, Doris R., Vertino, Paula M., Singh, Shivendra, Marcus, Adam I.
Publicado 2013

uPAR-targeted Optical Imaging Contrasts as Theranostic Agents for Tumor Margin Detection

por Yang, Lily, Sajja, Hari Krishna, Cao, Zehong, Qian, Weiping, Bender, Laura, Marcus, Adam I., Lipowska, Malgorzata, Wood, William C., Wang, Y. Andrew
Publicado 2013

Modulation of choroidal neovascularization by subretinal injection of retinal pigment epithelium and polystyrene microbeads

por Schmack, Ingo, Berglin, Lennart, Nie, Xiaoyan, Wen, Jing, Kang, Shin J., Marcus, Adam I, Yang, Hua, Lynn, Michael J., Kapp, Judith A, Grossniklaus, Hans E.
Publicado 2009

A live-cell platform to isolate phenotypically defined subpopulations for spatial multi-omic profiling

por Khatib, Tala O., Amanso, Angelica M., Pedro, Brian, Knippler, Christina M., Summerbell, Emily R., Zohbi, Najdat M., Konen, Jessica M., Mouw, Janna K., Marcus, Adam I.
Publicado 2023

A live-cell platform to isolate phenotypically defined subpopulations for spatial multi-omic profiling

por Khatib, Tala O., Amanso, Angelica M., Knippler, Christina M., Pedro, Brian, Summerbell, Emily R., Zohbi, Najdat M., Konen, Jessica M., Mouw, Janna K., Marcus, Adam I.
Publicado 2023

Live-cell invasive phenotyping uncovers the ALK2/BMP6 iron homeostasis pathway as a therapeutic vulnerability in LKB1-mutant lung cancer

por Koo, Junghui, Seong, Chang-Soo, Parker, Rebecca E., Dwivedi, Bhakti, Arthur, Robert A., Dinasarapu, Ashok Reddy, Johnston, H. Richard, Claussen, Henry, Tucker-Burden, Carol, Ramalingam, Suresh S., Fu, Haian, Zhou, Wei, Marcus, Adam I., Gilbert-Ross, Melissa
Publicado 2023

Epigenetically heterogeneous tumor cells direct collective invasion through filopodia-driven fibronectin micropatterning

por Summerbell, Emily R., Mouw, Janna K., Bell, Joshua S. K., Knippler, Christina M., Pedro, Brian, Arnst, Jamie L., Khatib, Tala O., Commander, Rachel, Barwick, Benjamin G., Konen, Jessica, Dwivedi, Bhakti, Seby, Sandra, Kowalski, Jeanne, Vertino, Paula M., Marcus, Adam I.
Publicado 2020

A role for activated Cdc42 in glioblastoma multiforme invasion

por Okura, Hidehiro, Golbourn, Brian J., Shahzad, Uswa, Agnihotri, Sameer, Sabha, Nesrin, Krieger, Jonathan R., Figueiredo, Carlyn A., Chalil, Alan, Landon-Brace, Natalie, Riemenschneider, Alexandra, Arai, Hajime, Smith, Christian A., Xu, Songli, Kaluz, Stefan, Marcus, Adam I., Van Meir, Erwin G., Rutka, James T.
Publicado 2016

Loss of the endocytic tumor suppressor HD-PTP phenocopies LKB1 and promotes RAS-driven oncogenesis

por Seong, Chang-Soo, Huang, Chunzi, Boese, Austin C., Hou, Yuning, Koo, Junghui, Mouw, Janna K., Rupji, Manali, Joseph, Greg, Johnston, H. Richard, Claussen, Henry, Switchenko, Jeffrey M., Behera, Madhusmita, Churchman, Michelle, Kolesar, Jill M., Arnold, Susanne M., Kerrigan, Katie, Akerley, Wallace, Colman, Howard, Johns, Margaret A., Arciero, Cletus, Zhou, Wei, Marcus, Adam I., Ramalingam, Suresh S., Fu, Haian, Gilbert-Ross, Melissa
Publicado 2023