β(2)-Adrenergic Receptor Activation Suppresses the Rat Phenethylamine Hallucinogen-Induced Head Twitch Response: Hallucinogen-Induced Excitatory Post-synaptic Potentials as a Poten...

por Marek, Gerard J., Ramos, Brian P.
Publicado 2018

Safety, Pharmacokinetics, and Pharmacodynamics of ASP3662, a Novel 11β‐Hydroxysteroid Dehydrogenase Type 1 Inhibitor, in Healthy Young and Elderly Subjects

por Bellaire, Susan, Walzer, Mark, Wang, Tianli, Krauwinkel, Walter, Yuan, Nancy, Marek, Gerard J.
Publicado 2019

A randomized phase 1 single-dose polysomnography study of ASP8062, a GABA(B) receptor positive allosteric modulator

por Walzer, Mark, Wu, Ruishan, Ahmad, Maha, Freeman, Jon, Zammit, Gary, Marek, Gerard J.
Publicado 2021

Pharmacokinetics of ASP4345 from Single Ascending-Dose and Multiple Ascending-Dose Phase I Studies

por Desai, Amit, Benner, Lauren, Wu, Ruishan, Gertsik, Lev, Uz, Tolga, Marek, Gerard J., Zhu, Tong
Publicado 2020

Efficacy and Safety of ASP0819 in Patients with Fibromyalgia: Results of a Proof-of-Concept, Randomized, Double-Blind, Placebo-Controlled Trial

por Arnold, Leslie M, Blauwet, Mary Beth, Tracy, Katherine, Cai, Na, Walzer, Mark, Blahunka, Paul, Marek, Gerard J
Publicado 2020

Metabotropic Glutamate(2) Receptors Play a Key Role in Modulating Head Twitches Induced by a Serotonergic Hallucinogen in Mice

por Benvenga, Mark J., Chaney, Stephen F., Baez, Melvyn, Britton, Thomas C., Hornback, William J., Monn, James A., Marek, Gerard J.
Publicado 2018

Phase 1 randomized study on the safety, tolerability, and pharmacodynamic cognitive and electrophysiological effects of a dopamine D(1) receptor positive allosteric modulator in pa...

por Desai, Amit, Benner, Lauren, Wu, Ruishan, Gertsik, Lev, Maruff, Paul, Light, Gregory A., Uz, Tolga, Marek, Gerard J., Zhu, Tong
Publicado 2020

Single‐ and multiple‐dose safety, tolerability, pharmacokinetic, and pharmacodynamic profiles of ASP0367, or bocidelpar sulfate, a novel modulator of peroxisome proliferator‐activa...

por Ito, Mototsugu, Tauscher‐Wisniewski, Sitra, Smulders, Ronald A., Wojtkowski, Tomasz, Yamada, Akihiro, Koibuchi, Akira, Uz, Tolga, Marek, Gerard J., Goldwater, Ronald D.
Publicado 2021

APOE-ɛ4 Carrier Status and Donepezil Response in Patients with Alzheimer’s Disease

por Waring, Jeffrey F., Tang, Qi, Robieson, Weining Z., King, David P., Das, Ujjwal, Dubow, Jordan, Dutta, Sandeep, Marek, Gerard J., Gault, Laura M.
Publicado 2015

Default-Mode-Like Network Activation in Awake Rodents

por Upadhyay, Jaymin, Baker, Scott J., Chandran, Prasant, Miller, Loan, Lee, Younglim, Marek, Gerard J., Sakoglu, Unal, Chin, Chih-Liang, Luo, Feng, Fox, Gerard B., Day, Mark
Publicado 2011