Integrative Structural Modelling of the Cardiac Thin Filament: Energetics at the Interface and Conservation Patterns Reveal a Spotlight on Period 2 of Tropomyosin

por Margaret Sunitha, S, Mercer, John A., Spudich, James A., Sowdhamini, Ramanathan
Publicado 2012

Genome-wide discovery for diabetes-dependent triglycerides-associated loci

por Selvaraj, Margaret Sunitha, Paruchuri, Kaavya, Haidermota, Sara, Bernardo, Rachel, Rich, Stephen S., Peloso, Gina M., Natarajan, Pradeep
Publicado 2022

Demonstrating paths for unlocking the value of cloud genomics through cross cohort analysis

por Deflaux, Nicole, Selvaraj, Margaret Sunitha, Condon, Henry Robert, Mayo, Kelsey, Haidermota, Sara, Basford, Melissa A., Lunt, Chris, Philippakis, Anthony A., Roden, Dan M., Denny, Joshua C., Musick, Anjene, Collins, Rory, Allen, Naomi, Effingham, Mark, Glazer, David, Natarajan, Pradeep, Bick, Alexander G.
Publicado 2023

A statistical framework for powerful multi-trait rare variant analysis in large-scale whole-genome sequencing studies

por Li, Xihao, Chen, Han, Selvaraj, Margaret Sunitha, Van Buren, Eric, Zhou, Hufeng, Wang, Yuxuan, Sun, Ryan, McCaw, Zachary R., Yu, Zhi, Arnett, Donna K., Bis, Joshua C., Blangero, John, Boerwinkle, Eric, Bowden, Donald W., Brody, Jennifer A., Cade, Brian E., Carson, April P., Carlson, Jenna C., Chami, Nathalie, Chen, Yii-Der Ida, Curran, Joanne E., de Vries, Paul S., Fornage, Myriam, Franceschini, Nora, Freedman, Barry I., Gu, Charles, Heard-Costa, Nancy L., He, Jiang, Hou, Lifang, Hung, Yi-Jen, Irvin, Marguerite R., Kaplan, Robert C., Kardia, Sharon L.R., Kelly, Tanika, Konigsberg, Iain, Kooperberg, Charles, Kral, Brian G., Li, Changwei, Loos, Ruth J.F., Mahaney, Michael C., Martin, Lisa W., Mathias, Rasika A., Minster, Ryan L., Mitchell, Braxton D., Montasser, May E., Morrison, Alanna C., Palmer, Nicholette D., Peyser, Patricia A., Psaty, Bruce M., Raffield, Laura M., Redline, Susan, Reiner, Alexander P., Rich, Stephen S., Sitlani, Colleen M., Smith, Jennifer A., Taylor, Kent D., Tiwari, Hemant, Vasan, Ramachandran S., Wang, Zhe, Yanek, Lisa R., Yu, Bing, Rice, Kenneth M., Rotter, Jerome I., Peloso, Gina M., Natarajan, Pradeep, Li, Zilin, Liu, Zhonghua, Lin, Xihong
Publicado 2023

Rare variants in long non-coding RNAs are associated with blood lipid levels in the TOPMed Whole Genome Sequencing Study

por Wang, Yuxuan, Selvaraj, Margaret Sunitha, Li, Xihao, Li, Zilin, Holdcraft, Jacob A., Arnett, Donna K., Bis, Joshua C., Blangero, John, Boerwinkle, Eric, Bowden, Donald W., Cade, Brian E., Carlson, Jenna C., Carson, April P., Chen, Yii-Der Ida, Curran, Joanne E., de Vries, Paul S., Dutcher, Susan K., Ellinor, Patrick T., Floyd, James S., Fornage, Myriam, Freedman, Barry I., Gabriel, Stacey, Germer, Soren, Gibbs, Richard A., Guo, Xiuqing, He, Jiang, Heard-Costa, Nancy, Hildalgo, Bertha, Hou, Lifang, Irvin, Marguerite R., Joehanes, Roby, Kaplan, Robert C., Kardia, Sharon LR., Kelly, Tanika N., Kim, Ryan, Kooperberg, Charles, Kral, Brian G., Levy, Daniel, Li, Changwei, Liu, Chunyu, Lloyd-Jone, Don, Loos, Ruth JF., Mahaney, Michael C., Martin, Lisa W., Mathias, Rasika A., Minster, Ryan L., Mitchell, Braxton D., Montasser, May E., Morrison, Alanna C., Murabito, Joanne M., Naseri, Take, O’Connell, Jeffrey R., Palmer, Nicholette D., Preuss, Michael H., Psaty, Bruce M., Raffield, Laura M., Rao, Dabeeru C., Redline, Susan, Reiner, Alexander P., Rich, Stephen S., Ruepena, Muagututi’a Sefuiva, Sheu, Wayne H-H., Smith, Jennifer A., Smith, Albert, Tiwari, Hemant K., Tsai, Michael Y., Viaud-Martinez, Karine A., Wang, Zhe, Yanek, Lisa R., Zhao, Wei, Rotter, Jerome I., Lin, Xihong, Natarajan, Pradeep, Peloso, Gina M.
Publicado 2023

Whole genome sequence analysis of blood lipid levels in >66,000 individuals

por Selvaraj, Margaret Sunitha, Li, Xihao, Li, Zilin, Pampana, Akhil, Zhang, David Y., Park, Joseph, Aslibekyan, Stella, Bis, Joshua C., Brody, Jennifer A., Cade, Brian E., Chuang, Lee-Ming, Chung, Ren-Hua, Curran, Joanne E., de las Fuentes, Lisa, de Vries, Paul S., Duggirala, Ravindranath, Freedman, Barry I., Graff, Mariaelisa, Guo, Xiuqing, Heard-Costa, Nancy, Hidalgo, Bertha, Hwu, Chii-Min, Irvin, Marguerite R., Kelly, Tanika N., Kral, Brian G., Lange, Leslie, Li, Xiaohui, Lisa, Martin, Lubitz, Steven A., Manichaikul, Ani W., Michael, Preuss, Montasser, May E., Morrison, Alanna C., Naseri, Take, O’Connell, Jeffrey R., Palmer, Nicholette D., Peyser, Patricia A., Reupena, Muagututia S., Smith, Jennifer A., Sun, Xiao, Taylor, Kent D., Tracy, Russell P., Tsai, Michael Y., Wang, Zhe, Wang, Yuxuan, Bao, Wei, Wilkins, John T., Yanek, Lisa R., Zhao, Wei, Arnett, Donna K., Blangero, John, Boerwinkle, Eric, Bowden, Donald W., Chen, Yii-Der Ida, Correa, Adolfo, Cupples, L. Adrienne, Dutcher, Susan K., Ellinor, Patrick T., Fornage, Myriam, Gabriel, Stacey, Germer, Soren, Gibbs, Richard, He, Jiang, Kaplan, Robert C., Kardia, Sharon L. R., Kim, Ryan, Kooperberg, Charles, Loos, Ruth J. F., Viaud-Martinez, Karine A, Mathias, Rasika A., McGarvey, Stephen T., Mitchell, Braxton D., Nickerson, Deborah, North, Kari E., Psaty, Bruce M., Redline, Susan, Reiner, Alexander P., Vasan, Ramachandran S., Rich, Stephen S., Willer, Cristen, Rotter, Jerome I., Rader, Daniel J., Lin, Xihong, Peloso, Gina M., Natarajan, Pradeep
Publicado 2022