Carcinogenesis: Fundamental Mechanisms and Environmental Effects

por Margison, G.
Publicado 1982

Expression in mammalian cells of the Escherichia coli O6 alkylguanine-DNA-alkyltransferase gene ogt reduces the toxicity of alkylnitrosoureas.

por Harris, L. C., Margison, G. P.
Publicado 1993

Dosage and cycle effects of dacarbazine (DTIC) and fotemustine on O6-alkylguanine-DNA alkyltransferase in human peripheral blood mononuclear cells.

por Lee, S. M., Thatcher, N., Dougal, M., Margison, G. P.
Publicado 1993

Inactivation of O6-alkylguanine-DNA alkyltransferase in human peripheral blood mononuclear cells by temozolomide.

por Lee, S. M., Thatcher, N., Crowther, D., Margison, G. P.
Publicado 1994

O6-alkylguanine-DNA-alkyltransferase activity and nitrosourea sensitivity in human cancer cell lines.

por Walker, M. C., Masters, J. R., Margison, G. P.
Publicado 1992

Sequential administration of varying doses of dacarbazine and fotemustine in advanced malignant melanoma.

por Lee, S. M., Margison, G. P., Woodcock, A. A., Thatcher, N.
Publicado 1993

Effect of chronic N,N-diethylnitrosamine on the excision of O6-ethylguanine from rat liver DNA.

por Margison, G. P., Curtin, N. J., Snell, K., Craig, A. W.
Publicado 1979

Immunohistochemical analysis of expression and allelotype of mismatch repair genes (hMLH1 and hMSH2) in bladder cancer

por Kassem, H Sh, Varley, J M, Hamam, S M, Margison, G P
Publicado 2001

Fern spore extracts can damage DNA

por Simán, S E, Povey, A C, Ward, T H, Margison, G P, Sheffield, E
Publicado 2000

Formation and loss of O6-methyldeoxyguanosine in human leucocyte DNA following sequential DTIC and fotemustine chemotherapy.

por Lee, S. M., Margison, G. P., Thatcher, N., O'Connor, P. J., Cooper, D. P.
Publicado 1994

Differential radiosensitisation by ZD1839 (Iressa), a highly selective epidermal growth factor receptor tyrosine kinase inhibitor in two related bladder cancer cell lines

por Maddineni, S B, Sangar, V K, Hendry, J H, Margison, G P, Clarke, N W
Publicado 2005

An evaluation of gemcitabines differential radiosensitising effect in related bladder cancer cell lines

por Sangar, V K, Cowan, R, Margison, G P, Hendry, J H, Clarke, N W
Publicado 2004

Influence of O(6)-benzylguanine on the anti-tumour activity and normal tissue toxicity of 1,3-bis(2-chloroethyl)-1-nitrosourea and molecular combinations of 5-fluorouracil and 2-ch...

por Bibby, M C, Thompson, M J, Rafferty, J A, Margison, G P, McElhinney, R S
Publicado 1999

Depletion of O6-alkylguanine-DNA alkyltransferase correlates with potentiation of temozolomide and CCNU toxicity in human tumour cells.

por Baer, J. C., Freeman, A. A., Newlands, E. S., Watson, A. J., Rafferty, J. A., Margison, G. P.
Publicado 1993

Expression of Ku70 correlates with survival in carcinoma of the cervix

por Wilson, C R, Davidson, S E, Margison, G P, Jackson, S P, Hendry, J H, West, C M L
Publicado 2000

Longitudinal variation in O(6)-alkylguanine DNA-alkyltransferase activity in the human colon and rectum

por Lees, N P, Harrison, K L, Hill, E, Hall, C N, Margison, G P, Povey, A C
Publicado 2002

Cyclophosphamide decreases O6-alkylguanine-DNA alkyltransferase activity in peripheral lymphocytes of patients undergoing bone marrow transplantation.

por Lee, S. M., Crowther, D., Scarffe, J. H., Dougal, M., Elder, R. H., Rafferty, J. A., Margison, G. P.
Publicado 1992

Phase II study of SPI-77 (sterically stabilised liposomal cisplatin) in advanced non-small-cell lung cancer

por White, S C, Lorigan, P, Margison, G P, Margison, J M, Martin, F, Thatcher, N, Anderson, H, Ranson, M
Publicado 2006

O(6)-(4-bromothenyl)guanine reverses temozolomide resistance in human breast tumour MCF-7 cells and xenografts

por Clemons, M, Kelly, J, Watson, A J, Howell, A, McElhinney, R S, McMurry, T B H, Margison, G P
Publicado 2005

Heterogeneity of O(6)-alkylguanine DNA-alkyltransferase expression in human breast tumours

por Clemons, M J, Bibby, M C, El Teraifi, H, Forster, G, Kelly, J, Banerjee, S, Cadman, B, Ryder, W D J, Howell, A, Margison, G P
Publicado 2002