Use of single guided Cas9 nickase to facilitate precise and efficient genome editing in human iPSCs

por Li, Pan P., Margolis, Russell L.
Publicado 2021

Diced Triplets Expose Neurons to RISC

por Rudnicki, Dobrila D., Margolis, Russell L., Pearson, Christopher E., Krzyzosiak, Wlodzimierz J.
Publicado 2012

Emerging differences between Huntington's disease-like 2 and Huntington's disease: A comparison using MRI brain volumetry

por Anderson, David G., Haagensen, Mark, Ferreira-Correia, Aline, Pierson, Ronald, Carr, Jonathan, Krause, Amanda, Margolis, Russell L.
Publicado 2019

Astrocytes generated from patient induced pluripotent stem cells recapitulate features of Huntington’s disease patient cells

por Juopperi, Tarja A, Kim, Woon Ryoung, Chiang, Cheng-Hsuan, Yu, Huimei, Margolis, Russell L, Ross, Christopher A, Ming, Guo-li, Song, Hongjun
Publicado 2012

Absence of Acanthocytosis in Huntington’s Disease-like 2: A Prospective Comparison with Huntington’s Disease

por Anderson, David G., Carmona, Sergio, Naidoo, Kubendran, Coetzer, Theresa L., Carr, Jonathan, Rudnicki, Dobrila D., Walker, Ruth H., Margolis, Russell L., Krause, Amanda
Publicado 2017

F177. THALAMIC SUBREGION RESTING STATE CONNECTIVITY IN SCHIZOPHRENIA MEASURED AT 7T

por Hua, Jun, Choe, Ann, Blair, Nicholas, Barber, Anita, Brandt, Allison, Pekar, James, van Zijl, Peter, Ross, Christopher, Lim, Issel, Xu, Feng, Margolis, Russell
Publicado 2018

Perspectives on the Use of eHealth in the Management of Patients With Schizophrenia

por Treisman, Glenn J., Jayaram, Geetha, Margolis, Russell L., Pearlson, Godfrey D., Schmidt, Chester W., Mihelish, Gary L., Kennedy, Adrienne, Howson, Alexandra, Rasulnia, Maziar, Misiuta, Iwona E.
Publicado 2016

FXTAS is rare among Portuguese patients with movement disorders: FMR1 premutations may be associated with a wider spectrum of phenotypes

por Seixas, Ana I, Vale, José, Jorge, Paula, Marques, Isabel, Santos, Rosário, Alonso, Isabel, Fortuna, Ana M, Pinto-Basto, Jorge, Coutinho, Paula, Margolis, Russell L, Sequeiros, Jorge, Silveira, Isabel
Publicado 2011

Nuclear retention of full-length HTT RNA is mediated by splicing factors MBNL1 and U2AF65

por Sun, Xin, Li, Pan P., Zhu, Shanshan, Cohen, Rachael, Marque, Leonard O., Ross, Christopher A., Pulst, Stefan M., Chan, Ho Yin Edwin, Margolis, Russell L., Rudnicki, Dobrila D.
Publicado 2015

RNA Toxicity and Perturbation of rRNA Processing in Spinocerebellar Ataxia Type 2

por Li, Pan P., Moulick, Roumita, Feng, Hongxuan, Sun, Xin, Arbez, Nicolas, Jin, Jing, Marque, Leonard O., Hedglen, Erin, Chan, H.Y. Edwin, Ross, Christopher A., Pulst, Stefan M., Margolis, Russell L., Woodson, Sarah, Rudnicki, Dobrila D.
Publicado 2021

A high-throughput screening to identify small molecules that suppress huntingtin promoter activity or activate huntingtin-antisense promoter activity

por Khaled, Houda G., Feng, Hongxuan, Hu, Xin, Sun, Xin, Zheng, Wang, Li, Pan P., Rudnicki, Dobrila D., Ye, Wenjuan, Chen, Yu-Chi, Southall, Noel, Marugan, Juan, Ross, Christopher A., Ferrer, Marc, Henderson, Mark J., Margolis, Russell L.
Publicado 2021

Pharmacological rescue in patient iPSC and mouse models with a rare DISC1 mutation

por Kim, Nam-Shik, Wen, Zhexing, Liu, Jing, Zhou, Ying, Guo, Ziyuan, Xu, Chongchong, Lin, Yu-Ting, Yoon, Ki-Jun, Park, Junhyun, Cho, Michelle, Kim, Minji, Wang, Xinyuan, Yu, Huimei, Sakamuru, Srilatha, Christian, Kimberly M., Hsu, Kuei-sen, Xia, Menghang, Li, Weidong, Ross, Christopher A., Margolis, Russell L., Lu, Xin-Yun, Song, Hongjun, Ming, Guo-li
Publicado 2021

Author Correction: Pharmacological rescue in patient iPSC and mouse models with a rare DISC1 mutation

por Kim, Nam-Shik, Wen, Zhexing, Liu, Jing, Zhou, Ying, Guo, Ziyuan, Xu, Chongchong, Lin, Yu-Ting, Yoon, Ki-Jun, Park, Junhyun, Cho, Michelle, Kim, Minji, Wang, Xinyuan, Yu, Huimei, Sakamuru, Srilatha, Christian, Kimberly M., Hsu, Kuei-sen, Xia, Menghang, Li, Weidong, Ross, Christopher A., Margolis, Russell L., Lu, Xin-Yun, Song, Hongjun, Ming, Guo-li
Publicado 2021

Population stratification may bias analysis of PGC-1α as a modifier of age at Huntington disease motor onset

por Ramos, Eliana Marisa, Latourelle, Jeanne C., Lee, Ji-Hyun, Gillis, Tammy, Mysore, Jayalakshmi S., Squitieri, Ferdinando, Di Pardo, Alba, Di Donato, Stefano, Hayden, Michael R., Morrison, Patrick J., Nance, Martha, Ross, Christopher A., Margolis, Russell L., Gomez-Tortosa, Estrella, Ayuso, Carmen, Suchowersky, Oksana, Trent, Ronald J., McCusker, Elizabeth, Novelletto, Andrea, Frontali, Marina, Jones, Randi, Ashizawa, Tetsuo, Frank, Samuel, Saint-Hilaire, Marie-Helene, Hersch, Steven M., Rosas, Herminia D., Lucente, Diane, Harrison, Madaline B., Zanko, Andrea, Marder, Karen, Gusella, James F., Lee, Jong-Min, Alonso, Isabel, Sequeiros, Jorge, Myers, Richard H., MacDonald, Marcy E.
Publicado 2012

Candidate glutamatergic and dopaminergic pathway gene variants do not influence Huntington’s disease motor onset

por Ramos, Eliana Marisa, Latourelle, Jeanne C., Gillis, Tammy, Mysore, Jayalakshmi S., Squitieri, Ferdinando, Di Pardo, Alba, Di Donato, Stefano, Gellera, Cinzia, Hayden, Michael R., Morrison, Patrick J., Nance, Martha, Ross, Christopher A., Margolis, Russell L., Gomez-Tortosa, Estrella, Ayuso, Carmen, Suchowersky, Oksana, Trent, Ronald J., McCusker, Elizabeth, Novelletto, Andrea, Frontali, Marina, Jones, Randi, Ashizawa, Tetsuo, Frank, Samuel, Saint-Hilaire, Marie-Helene, Hersch, Steven M., Rosas, Herminia D., Lucente, Diane, Harrison, Madaline B., Zanko, Andrea, Abramson, Ruth K., Marder, Karen, Gusella, James F., Lee, Jong-Min, Alonso, Isabel, Sequeiros, Jorge, Myers, Richard H., MacDonald, Marcy E.
Publicado 2013

Genome-wide significance for a modifier of age at neurological onset in Huntington's Disease at 6q23-24: the HD MAPS study

por Li, Jian-Liang, Hayden, Michael R, Warby, Simon C, Durr, Alexandra, Morrison, Patrick J, Nance, Martha, Ross, Christopher A, Margolis, Russell L, Rosenblatt, Adam, Squitieri, Ferdinando, Frati, Luigi, Gómez-Tortosa, Estrella, García, Carmen Ayuso, Suchowersky, Oksana, Klimek, Mary Lou, Trent, Ronald JA, McCusker, Elizabeth, Novelletto, Andrea, Frontali, Marina, Paulsen, Jane S, Jones, Randi, Ashizawa, Tetsuo, Lazzarini, Alice, Wheeler, Vanessa C, Prakash, Ranjana, Xu, Gang, Djoussé, Luc, Mysore, Jayalakshmi Srinidhi, Gillis, Tammy, Hakky, Michael, Cupples, L Adrienne, Saint-Hilaire, Marie H, Cha, Jang-Ho J, Hersch, Steven M, Penney, John B, Harrison, Madaline B, Perlman, Susan L, Zanko, Andrea, Abramson, Ruth K, Lechich, Anthony J, Duckett, Ayana, Marder, Karen, Conneally, P Michael, Gusella, James F, MacDonald, Marcy E, Myers, Richard H
Publicado 2006