YWHAE-NUTM2 oncoprotein regulates proliferation and cyclin D1 via RAF/MAPK and Hippo pathways

por Ou, Wen-Bin, Lundberg, Meijun Z., Zhu, Shuihao, Bahri, Nacef, Kyriazoglou, Anastasios, Xu, Liangliang, Chen, Ting, Mariño-Enriquez, Adrian, Fletcher, Jonathan A.
Publicado 2021

Inhibitor of Apoptosis Proteins (IAPs) are commonly dysregulated in GIST and can be pharmacologically targeted to enhance the pro-apoptotic activity of imatinib

por Falkenhorst, Johanna, Grunewald, Susanne, Mühlenberg, Thomas, Marino-Enriquez, Adrian, Reis, Anna-Carina, Corless, Christopher, Heinrich, Michael, Treckmann, Jürgen, Podleska, Lars Erik, Schuler, Martin, Fletcher, Jonathan Alfred, Bauer, Sebastian
Publicado 2016

HDACi inhibits liposarcoma via targeting of the MDM2-p53 signaling axis and PTEN, irrespective of p53 mutational status

por Ou, Wen-Bin, Zhu, Jiaqing, Eilers, Grant, Li, Xuhui, Kuang, Ye, Liu, Li, Mariño-Enríquez, Adrián, Yan, Ziqin, Li, Hailong, Meng, Fanguo, Zhou, Haimeng, Sheng, Qing, Fletcher, Jonathan A.
Publicado 2015

Coordinated targeting of CK2 and KIT in gastrointestinal stromal tumours

por Huang, Mengyuan, Yang, Wenyu, Zhu, Jiaqing, Mariño-Enríquez, Adrián, Zhu, Chennianci, Chen, Jiaming, Wu, Yuehong, Quan, Yanping, Qiu, Haibo, Li, Xuhui, Chai, Li, Fletcher, Jonathan A., Ou, Wen-Bin
Publicado 2019

Response and Mechanisms of Resistance to Larotrectinib and Selitrectinib in Metastatic Undifferentiated Sarcoma Harboring Oncogenic Fusion of NTRK1

por Hemming, Matthew L., Nathenson, Michael J., Lin, Jia-Ren, Mei, Shaolin, Du, Ziming, Malik, Karan, Marino-Enriquez, Adrian, Jagannathan, Jyothi P., Sorger, Peter K., Bertagnolli, Monica, Sicinska, Ewa, Demetri, George D., Santagata, Sandro
Publicado 2020

Inhibition of Bcl-2 family members sensitises soft tissue leiomyosarcomas to chemotherapy

por de Graaff, Marieke A, de Rooij, Marije A J, van den Akker, Brendy E W M, Gelderblom, Hans, Chibon, Fréderic, Coindre, Jean-Michel, Marino-Enriquez, Adrian, Fletcher, Jonathan A, Cleton-Jansen, Anne-Marie, Bovée, Judith V M G
Publicado 2016

Angiogenesis-Related Gene Expression Profile with Independent Prognostic Value in Advanced Ovarian Carcinoma

por Mendiola, Marta, Barriuso, Jorge, Redondo, Andrés, Mariño-Enríquez, Adrián, Madero, Rosario, Espinosa, Enrique, Vara, Juan Ángel Fresno, Sánchez-Navarro, Iker, Hernández-Cortes, Ginés, Zamora, Pilar, Pérez-Fernández, Elia, Miguel-Martín, María, Suárez, Asunción, Palacios, José, González-Barón, Manuel, Hardisson, David
Publicado 2008

Complementary activity of tyrosine kinase inhibitors against secondary kit mutations in imatinib-resistant gastrointestinal stromal tumours

por Serrano, César, Mariño-Enríquez, Adrián, Tao, Derrick L., Ketzer, Julia, Eilers, Grant, Zhu, Meijun, Yu, Channing, Mannan, Aristotle M., Rubin, Brian P., Demetri, George D., Raut, Chandrajit P., Presnell, Ajia, McKinley, Arin, Heinrich, Michael C., Czaplinski, Jeffrey T., Sicinska, Ewa, Bauer, Sebastian, George, Suzanne, Fletcher, Jonathan A.
Publicado 2019

Correction: Complementary activity of tyrosine kinase inhibitors against secondary kit mutations in imatinib-resistant gastrointestinal stromal tumours

por Serrano, César, Mariño-Enríquez, Adrián, Tao, Derrick L., Ketzer, Julia, Eilers, Grant, Zhu, Meijun, Yu, Channing, Mannan, Aristotle M., Rubin, Brian P., Demetri, George D., Raut, Chandrajit P., Presnell, Ajia, McKinley, Arin, Heinrich, Michael C., Czaplinski, Jeffrey T., Sicinska, Ewa, Bauer, Sebastian, George, Suzanne, Fletcher, Jonathan A.
Publicado 2019

Dystrophin Is a Tumor Suppressor in Human Cancers with Myogenic Programs

por Wang, Yuexiang, Marino-Enriquez, Adrian, Bennett, Richard R., Zhu, Meijun, Shen, Yiping, Eilers, Grant, Lee, Jen-Chieh, Henze, Joern, Fletcher, Benjamin S., Gu, Zhizhan, Fox, Edward A., Antonescu, Cristina R., Fletcher, Christopher D.M., Guo, Xiangqian, Raut, Chandrajit P., Demetri, George D., van de Rijn, Matt, Ordog, Tamas, Kunkel, Louis M., Fletcher, Jonathan A.
Publicado 2014

MAX inactivation is an early event in GIST development that regulates p16 and cell proliferation

por Schaefer, Inga-Marie, Wang, Yuexiang, Liang, Cher-wei, Bahri, Nacef, Quattrone, Anna, Doyle, Leona, Mariño-Enríquez, Adrian, Lauria, Alexandra, Zhu, Meijun, Debiec-Rychter, Maria, Grunewald, Susanne, Hechtman, Jaclyn F., Dufresne, Armelle, Antonescu, Cristina R., Beadling, Carol, Sicinska, Ewa T., van de Rijn, Matt, Demetri, George D., Ladanyi, Marc, Corless, Christopher L., Heinrich, Michael C., Raut, Chandrajit P., Bauer, Sebastian, Fletcher, Jonathan A.
Publicado 2017