Beyond radio-displacement techniques for Identification of CB(1) Ligands: The First Application of a Fluorescence-quenching Assay

por Bruno, Agostino, Lembo, Francesca, Novellino, Ettore, Stornaiuolo, Mariano, Marinelli, Luciana
Publicado 2014

A Healthy Balance of Plasma Cholesterol by a Novel Annurca Apple-Based Nutraceutical Formulation: Results of a Randomized Trial

por Tenore, Gian Carlo, Caruso, Domenico, Buonomo, Giuseppe, D'Avino, Maria, Campiglia, Pietro, Marinelli, Luciana, Novellino, Ettore
Publicado 2017

Endogenous vs Exogenous Allosteric Modulators in GPCRs: A dispute for shuttling CB(1) among different membrane microenvironments

por Stornaiuolo, Mariano, Bruno, Agostino, Botta, Lorenzo, Regina, Giuseppe La, Cosconati, Sandro, Silvestri, Romano, Marinelli, Luciana, Novellino, Ettore
Publicado 2015

Long lasting MDM2/Translocator protein modulator: a new strategy for irreversible apoptosis of human glioblastoma cells

por Daniele, Simona, Barresi, Elisabetta, Zappelli, Elisa, Marinelli, Luciana, Novellino, Ettore, Da Settimo, Federico, Taliani, Sabrina, Trincavelli, Maria L., Martini, Claudia
Publicado 2016

Click‐Chemistry (CuAAC) Trimerization of an α(v)β(6) Integrin Targeting Ga‐68‐Peptide: Enhanced Contrast for in‐Vivo PET Imaging of Human Lung Adenocarcinoma Xenografts

por Quigley, Neil Gerard, Tomassi, Stefano, di Leva, Francesco Saverio, Di Maro, Salvatore, Richter, Frauke, Steiger, Katja, Kossatz, Susanne, Marinelli, Luciana, Notni, Johannes
Publicado 2020

Combined inhibition of AKT/mTOR and MDM2 enhances Glioblastoma Multiforme cell apoptosis and differentiation of cancer stem cells

por Daniele, Simona, Costa, Barbara, Zappelli, Elisa, Da Pozzo, Eleonora, Sestito, Simona, Nesi, Giulia, Campiglia, Pietro, Marinelli, Luciana, Novellino, Ettore, Rapposelli, Simona, Martini, Claudia
Publicado 2015

Molecular View on the iRGD Peptide Binding Mechanism: Implications for Integrin Activity and Selectivity Profiles

por D’Amore, Vincenzo Maria, Donati, Greta, Lenci, Elena, Ludwig, Beatrice Stefanie, Kossatz, Susanne, Baiula, Monica, Trabocchi, Andrea, Kessler, Horst, Di Leva, Francesco Saverio, Marinelli, Luciana
Publicado 2023

Dihydrotanshinone-I interferes with the RNA-binding activity of HuR affecting its post-transcriptional function

por D’Agostino, Vito Giuseppe, Lal, Preet, Mantelli, Barbara, Tiedje, Christopher, Zucal, Chiara, Thongon, Natthakan, Gaestel, Matthias, Latorre, Elisa, Marinelli, Luciana, Seneci, Pierfausto, Amadio, Marialaura, Provenzani, Alessandro
Publicado 2015

Temozolomide-Acquired Resistance Is Associated with Modulation of the Integrin Repertoire in Glioblastoma, Impact of α5β1 Integrin

por Sani, Saidu, Pallaoro, Nikita, Messe, Mélissa, Bernhard, Chloé, Etienne-Selloum, Nelly, Kessler, Horst, Marinelli, Luciana, Entz-Werle, Natacha, Foppolo, Sophie, Martin, Sophie, Reita, Damien, Dontenwill, Monique
Publicado 2022

Targeting CXCR4 reverts the suppressive activity of T-regulatory cells in renal cancer

por Santagata, Sara, Napolitano, Maria, D'Alterio, Crescenzo, Desicato, Sonia, Maro, Salvatore Di, Marinelli, Luciana, Fragale, Alessandra, Buoncervello, Maria, Persico, Francesco, Gabriele, Lucia, Novellino, Ettore, Longo, Nicola, Pignata, Sandro, Perdonà, Sisto, Scala, Stefania
Publicado 2017

Characterization of 2,4-Diamino-6-oxo-1,6-dihydropyrimidin-5-yl Ureido Based Inhibitors of Trypanosoma brucei FolD and Testing for Antiparasitic Activity

por Eadsforth, Thomas C., Pinto, Andrea, Luciani, Rosaria, Tamborini, Lucia, Cullia, Gregorio, De Micheli, Carlo, Marinelli, Luciana, Cosconati, Sandro, Novellino, Ettore, Lo Presti, Leonardo, Cordeiro da Silva, Anabela, Conti, Paola, Hunter, William N., Costi, Maria P.
Publicado 2015

Apoptosis Therapy in Cancer: The First Single-molecule Co-activating p53 and the Translocator Protein in Glioblastoma

por Daniele, Simona, Taliani, Sabrina, Da Pozzo, Eleonora, Giacomelli, Chiara, Costa, Barbara, Trincavelli, Maria Letizia, Rossi, Leonardo, La Pietra, Valeria, Barresi, Elisabetta, Carotenuto, Alfonso, Limatola, Antonio, Lamberti, Anna, Marinelli, Luciana, Novellino, Ettore, Da Settimo, Federico, Martini, Claudia
Publicado 2014

Identification of a Novel p53 Modulator Endowed with Antitumoural and Antibacterial Activity through a Scaffold Repurposing Approach

por Nuti, Elisa, La Pietra, Valeria, Daniele, Simona, Cuffaro, Doretta, Ciccone, Lidia, Giacomelli, Chiara, Cason, Carolina, Carotenuto, Alfonso, D’Amore, Vincenzo Maria, Pozzo, Eleonora Da, Costa, Barbara, Di Leo, Riccardo, Comar, Manola, Marinelli, Luciana, Martini, Claudia, Rossello, Armando
Publicado 2022

Halting the Spread of Herpes Simplex Virus-1: The Discovery of an Effective Dual αvβ6/αvβ8 Integrin Ligand

por Tomassi, Stefano, D’Amore, Vincenzo Maria, Di Leva, Francesco Saverio, Vannini, Andrea, Quilici, Giacomo, Weinmüller, Michael, Reichart, Florian, Amato, Jussara, Romano, Barbara, Izzo, Angelo Antonio, Di Maro, Salvatore, Novellino, Ettore, Musco, Giovanna, Gianni, Tatiana, Kessler, Horst, Marinelli, Luciana
Publicado 2021

Enriching the Arsenal of Pharmacological Tools against MICAL2

por Barravecchia, Ivana, Barresi, Elisabetta, Russo, Camilla, Scebba, Francesca, De Cesari, Chiara, Mignucci, Valerio, De Luca, Davide, Salerno, Silvia, La Pietra, Valeria, Giustiniano, Mariateresa, Pelliccia, Sveva, Brancaccio, Diego, Donati, Greta, Da Settimo, Federico, Taliani, Sabrina, Angeloni, Debora, Marinelli, Luciana
Publicado 2021

Theoretical and experimental studies on the interaction of biphenyl ligands with human and murine PD-L1: Up-to-date clues for drug design

por Donati, Greta, D’Amore, Vincenzo Maria, Russomanno, Pasquale, Cerofolini, Linda, Amato, Jussara, Marzano, Simona, Salobehaj, Maria, Rizzo, Domenico, Assoni, Giulia, Carotenuto, Alfonso, La Pietra, Valeria, Arosio, Daniela, Seneci, Pierfausto, Fragai, Marco, Brancaccio, Diego, Di Leva, Francesco Saverio, Marinelli, Luciana
Publicado 2023

Retromer stabilization results in neuroprotection in a model of Amyotrophic Lateral Sclerosis

por Muzio, Luca, Sirtori, Riccardo, Gornati, Davide, Eleuteri, Simona, Fossaghi, Andrea, Brancaccio, Diego, Manzoni, Leonardo, Ottoboni, Linda, Feo, Luca De, Quattrini, Angelo, Mastrangelo, Eloise, Sorrentino, Luca, Scalone, Emanuele, Comi, Giancarlo, Marinelli, Luciana, Riva, Nilo, Milani, Mario, Seneci, Pierfausto, Martino, Gianvito
Publicado 2020

HuR modulation counteracts lipopolysaccharide response in murine macrophages

por Bonomo, Isabelle, Assoni, Giulia, La Pietra, Valeria, Canarutto, Giulia, Facen, Elisa, Donati, Greta, Zucal, Chiara, Genovese, Silvia, Micaelli, Mariachiara, Pérez-Ràfols, Anna, Robbiati, Sergio, Kontoyannis, Dimitris L., De Matteo, Marilenia, Fragai, Marco, Seneci, Pierfausto, Marinelli, Luciana, Arosio, Daniela, Piazza, Silvano, Provenzani, Alessandro
Publicado 2023

Novel Quinolinonyl Diketo Acid Derivatives as HIV-1 Integrase Inhibitors: Design, Synthesis, and Biological Activities

por Di Santo, Roberto, Costi, Roberta, Roux, Alessandra, Miele, Gaetano, Crucitti, Giuliana Cuzzucoli, Iacovo, Alberto, Rosi, Federica, Lavecchia, Antonio, Marinelli, Luciana, Di Giovanni, Carmen, Novellino, Ettore, Palmisano, Lucia, Andreotti, Mauro, Amici, Roberta, Galluzzo, Clementina Maria, Nencioni, Lucia, Palamara, Anna Teresa, Pommier, Yves, Marchand, Christophe
Publicado 2008

Basic Quinolinonyl Diketo Acid Derivatives as Inhibitors of HIV Integrase and their Activity against RNase H Function of Reverse Transcriptase

por Costi, Roberta, Métifiot, Mathieu, Chung, Suhman, Cuzzucoli Crucitti, Giuliana, Maddali, Kasthuraiah, Pescatori, Luca, Messore, Antonella, Madia, Valentina Noemi, Pupo, Giovanni, Scipione, Luigi, Tortorella, Silvano, Di Leva, Francesco Saverio, Cosconati, Sandro, Marinelli, Luciana, Novellino, Ettore, Le Grice, Stuart F. J., Corona, Angela, Pommier, Yves, Marchand, Christophe, Di Santo, Roberto
Publicado 2014