Pharmacokinetics of the CYP3A4 and CYP2B6 Inducer Carbamazepine and Its Drug–Drug Interaction Potential: A Physiologically Based Pharmacokinetic Modeling Approach

por Fuhr, Laura Maria, Marok, Fatima Zahra, Hanke, Nina, Selzer, Dominik, Lehr, Thorsten
Publicado 2021

Physiologically Based Pharmacokinetic Modeling of Bupropion and Its Metabolites in a CYP2B6 Drug-Drug-Gene Interaction Network

por Marok, Fatima Zahra, Fuhr, Laura Maria, Hanke, Nina, Selzer, Dominik, Lehr, Thorsten
Publicado 2021

A Physiologically Based Pharmacokinetic and Pharmacodynamic Model of the CYP3A4 Substrate Felodipine for Drug–Drug Interaction Modeling

por Fuhr, Laura Maria, Marok, Fatima Zahra, Mees, Maximilian, Mahfoud, Felix, Selzer, Dominik, Lehr, Thorsten
Publicado 2022

A Physiologically Based Pharmacokinetic Model of Ketoconazole and Its Metabolites as Drug–Drug Interaction Perpetrators

por Marok, Fatima Zahra, Wojtyniak, Jan-Georg, Fuhr, Laura Maria, Selzer, Dominik, Schwab, Matthias, Weiss, Johanna, Haefeli, Walter Emil, Lehr, Thorsten
Publicado 2023

Physiologically‐based pharmacokinetic modeling of quinidine to establish a CYP3A4, P‐gp, and CYP2D6 drug–drug–gene interaction network

por Feick, Denise, Rüdesheim, Simeon, Marok, Fatima Zahra, Selzer, Dominik, Loer, Helena Leonie Hanae, Teutonico, Donato, Frechen, Sebastian, van der Lee, Maaike, Moes, Dirk Jan A. R., Swen, Jesse J., Schwab, Matthias, Lehr, Thorsten
Publicado 2023