Intranasal Vaccination Promotes Detrimental Th17-Mediated Immunity against Influenza Infection

por Maroof, Asher, Yorgensen, Yvonne M., Li, Yufeng, Evans, Jay T.
Publicado 2014

Compartment-Specific Remodeling of Splenic Micro-Architecture during Experimental Visceral Leishmaniasis

por Yurdakul, Pinar, Dalton, Jane, Beattie, Lynette, Brown, Najmeeyah, Erguven, Sibel, Maroof, Asher, Kaye, Paul M.
Publicado 2011

Innate Killing of Leishmania donovani by Macrophages of the Splenic Marginal Zone Requires IRF-7

por Phillips, Rebecca, Svensson, Mattias, Aziz, Naveed, Maroof, Asher, Brown, Najmeeyah, Beattie, Lynette, Signoret, Nathalie, Kaye, Paul M.
Publicado 2010

Dual neutralisation of IL-17F and IL-17A with bimekizumab blocks inflammation-driven osteogenic differentiation of human periosteal cells

por Shah, Mittal, Maroof, Asher, Gikas, Panos, Mittal, Gayatri, Keen, Richard, Baeten, Dominique, Shaw, Stevan, Roberts, Scott J
Publicado 2020

Dynamic Imaging of Experimental Leishmania donovani-Induced Hepatic Granulomas Detects Kupffer Cell-Restricted Antigen Presentation to Antigen-Specific CD8(+) T Cells

por Beattie, Lynette, Peltan, Adam, Maroof, Asher, Kirby, Alun, Brown, Najmeeyah, Coles, Mark, Smith, Deborah F., Kaye, Paul M.
Publicado 2010

Leishmania donovani-induced expression of signal regulatory protein α on Kupffer cells enhances hepatic invariant NKT-cell activation

por Beattie, Lynette, Svensson, Mattias, Bune, Alison, Brown, Najmeeyah, Maroof, Asher, Zubairi, Soombul, Smith, Katharine R, Kaye, Paul M
Publicado 2010

Interleukin (IL)-12 and IL-18 Synergize to Promote MAIT Cell IL-17A and IL-17F Production Independently of IL-23 Signaling

por Cole, Suzanne, Murray, Janine, Simpson, Catherine, Okoye, Remi, Tyson, Kerry, Griffiths, Meryn, Baeten, Dominique, Shaw, Stevan, Maroof, Asher
Publicado 2020

Comparative Expression Profiling of Leishmania: Modulation in Gene Expression between Species and in Different Host Genetic Backgrounds

por Depledge, Daniel P., Evans, Krystal J., Ivens, Alasdair C., Aziz, Naveed, Maroof, Asher, Kaye, Paul M., Smith, Deborah F.
Publicado 2009

A Transcriptomic Network Identified in Uninfected Macrophages Responding to Inflammation Controls Intracellular Pathogen Survival

por Beattie, Lynette, d’El-Rei Hermida, Micely, Moore, John W.J., Maroof, Asher, Brown, Najmeeyah, Lagos, Dimitris, Kaye, Paul M.
Publicado 2013

B Cell: T Cell Interactions Occur within Hepatic Granulomas during Experimental Visceral Leishmaniasis

por Moore, John W. J., Beattie, Lynette, Dalton, Jane E., Owens, Benjamin M. J., Maroof, Asher, Coles, Mark C., Kaye, Paul M.
Publicado 2012

CD4(+) Recent Thymic Emigrants Are Recruited into Granulomas during Leishmania donovani Infection but Have Limited Capacity for Cytokine Production

por Moore, John W. J., Beattie, Lynette, Osman, Mohamed, Owens, Benjamin M. J., Brown, Najmeeyah, Dalton, Jane E., Maroof, Asher, Kaye, Paul M.
Publicado 2016

IL-10-Producing Th1 Cells and Disease Progression Are Regulated by Distinct CD11c(+) Cell Populations during Visceral Leishmaniasis

por Owens, Benjamin M. J., Beattie, Lynette, Moore, John W. J., Brown, Najmeeyah, Mann, Jason L., Dalton, Jane E., Maroof, Asher, Kaye, Paul M.
Publicado 2012

Bimekizumab, a Novel Humanized IgG1 Antibody That Neutralizes Both IL-17A and IL-17F

por Adams, Ralph, Maroof, Asher, Baker, Terry, Lawson, Alastair D. G., Oliver, Ruth, Paveley, Ross, Rapecki, Steve, Shaw, Stevan, Vajjah, Pavan, West, Shauna, Griffiths, Meryn
Publicado 2020

Therapeutic Vaccination With Recombinant Adenovirus Reduces Splenic Parasite Burden in Experimental Visceral Leishmaniasis

por Maroof, Asher, Brown, Najmeeyah, Smith, Barbara, Hodgkinson, Michael R., Maxwell, Alice, Losch, Florian O., Fritz, Ulrike, Walden, Peter, Lacey, Charles N. J., Smith, Deborah F., Aebischer, Toni, Kaye, Paul M.
Publicado 2012

Spatiotemporal Modeling of the Key Migratory Events During the Initiation of Adaptive Immunity

por Hayes, Alan J., Rane, Sanket, Scales, Hannah E., Meehan, Gavin R., Benson, Robert A., Maroof, Asher, Schroeder, Juliane, Tomura, Michio, Gozzard, Neil, Yates, Andrew J., Garside, Paul, Brewer, James M.
Publicado 2019

VCAM-1 and VLA-4 Modulate Dendritic Cell IL-12p40 Production in Experimental Visceral Leishmaniasis

por Stanley, Amanda C., Dalton, Jane E., Rossotti, Susanna H., MacDonald, Kelli P., Zhou, Yonghong, Rivera, Fabian, Schroder, Wayne A., Maroof, Asher, Hill, Geoff R., Kaye, Paul M., Engwerda, Christian R.
Publicado 2008

N-Myristoyltransferase from Leishmania donovani: Structural and Functional Characterisation of a Potential Drug Target for Visceral Leishmaniasis

por Brannigan, James A., Smith, Barbara A., Yu, Zhiyong, Brzozowski, Andrzej M., Hodgkinson, Michael R., Maroof, Asher, Price, Helen P., Meier, Franziska, Leatherbarrow, Robin J., Tate, Edward W., Smith, Deborah F., Wilkinson, Anthony J.
Publicado 2010

TRYBE®: an Fc-free antibody format with three monovalent targeting arms engineered for long in vivo half-life

por Davé, Emma, Durrant, Oliver, Dhami, Neha, Compson, Joanne, Broadbridge, Janice, Archer, Sophie, Maroof, Asher, Whale, Kevin, Menochet, Karelle, Bonnaillie, Pierre, Barry, Emily, Wild, Gavin, Peerboom, Claude, Bhatta, Pallavi, Ellis, Mark, Hinchliffe, Matthew, Humphreys, David P., Heywood, Sam P.
Publicado 2023