Synthetic Proteins and Peptides for the Direct Interrogation of α-Synuclein Posttranslational Modifications

por Pratt, Matthew R., Abeywardana, Tharindumala, Marotta, Nicholas P.
Publicado 2015

Distinct biological activity of Lewy body α-Synuclein strain in mice

por Uemura, Norihito, Marotta, Nicholas, Ara, Jahan, Meymand, Emily, Zhang, Bin, Kameda, Hiroshi, Koike, Masato, Luk, Kelvin, Trojanowski, John, Lee, Virginia
Publicado 2023

Alpha-synuclein from patient Lewy bodies exhibits distinct pathological activity that can be propagated in vitro

por Marotta, Nicholas P., Ara, Jahan, Uemura, Norihito, Lougee, Marshall G., Meymand, Emily S., Zhang, Bin, Petersson, E. James, Trojanowski, John Q., Lee, Virginia M.-Y.
Publicado 2021

α-Synuclein aggregates amplified from patient-derived Lewy bodies recapitulate Lewy body diseases in mice

por Uemura, Norihito, Marotta, Nicholas P., Ara, Jahan, Meymand, Emily S., Zhang, Bin, Kameda, Hiroshi, Koike, Masato, Luk, Kelvin C., Trojanowski, John Q., Lee, Virginia M.-Y.
Publicado 2023

O-GlcNAc modification blocks the aggregation and toxicity of the Parkinson’s disease associated protein α-synuclein

por Marotta, Nicholas P., Lin, Yu Hsuan, Lewis, Yuka E., Ambroso, Mark R., Zaro, Balyn W., Roth, Maxwell T., Arnold, Don B., Langen, Ralf, Pratt, Matthew R.
Publicado 2015