Broad-spectrum antiviral and cytocidal activity of cyclopentenylcytosine, a carbocyclic nucleoside targeted at CTP synthetase

por de Clercq, Erik, Murase, Junichi, Marquez, Victor E.
Publicado 1991

Coupling between conformational dynamics and catalytic function at the active site of the lead-dependent ribozyme

por White, Neil A., Sumita, Minako, Marquez, Victor E., Hoogstraten, Charles G.
Publicado 2018

Biophysical studies of DNA modified with conformationally constrained nucleotides: comparison of 2′-exo (north) and 3′-exo (south) ‘locked’ templates

por Maderia, Melissa, Shenoy, Shilpa, Van, Que N., Marquez, Victor E., Barchi, Joseph J.
Publicado 2007

Inhibition of histone methyltransferase EZH2 depletes leukemia stem cell of mixed lineage leukemia fusion leukemia through upregulation of p16

por Ueda, Koki, Yoshimi, Akihide, Kagoya, Yuki, Nishikawa, Satoshi, Marquez, Victor E, Nakagawa, Masahiro, Kurokawa, Mineo
Publicado 2014

Synthesis and Conformational Analysis of Locked Carbocyclic Analogues of 1,3-Diazepinone Riboside, a High-Affinity Cytidine Deaminase Inhibitor

por Ludek, Olaf R., Schroeder, Gottfried K., Liao, Chenzhong, Russ, Pamela L., Wolfenden, Richard, Marquez, Victor E.
Publicado 2009

Conformationally rigid nucleoside probes help understand the role of sugar pucker and nucleobase orientation in the thrombin-binding aptamer

por Saneyoshi, Hisao, Mazzini, Stefania, Aviñó, Anna, Portella, Guillem, González, Carlos, Orozco, Modesto, Marquez, Víctor E., Eritja, Ramon
Publicado 2009

Polycomb repressor complex 2 regulates HOXA9 and HOXA10, activating ID2 in NK/T-cell lines

por Nagel, Stefan, Venturini, Letizia, Marquez, Victor E, Meyer, Corinna, Kaufmann, Maren, Scherr, Michaela, MacLeod, Roderick AF, Drexler, Hans G
Publicado 2010

Diacylglycerol Lactones Targeting the Structural Features That Distinguish the Atypical C1 Domains of Protein Kinase C ζ and ι from Typical C1 Domains

por Pu, Yongmei, Kang, Ji-Hye, Sigano, Dina M., Peach, Megan L., Lewin, Nancy E., Marquez, Victor E., Blumberg, Peter M.
Publicado 2014

The protein tyrosine phosphatase receptor type R gene is an early and frequent target of silencing in human colorectal tumorigenesis

por Menigatti, Mirco, Cattaneo, Elisa, Sabates-Bellver, Jacob, Ilinsky, Valery V, Went, Philip, Buffoli, Federico, Marquez, Victor E, Jiricny, Josef, Marra, Giancarlo
Publicado 2009

Pharmacologic disruption of Polycomb Repressive Complex 2 inhibits tumorigenicity and tumor progression in prostate cancer

por Crea, Francesco, Hurt, Elaine M, Mathews, Lesley A, Cabarcas, Stephanie M, Sun, Lei, Marquez, Victor E, Danesi, Romano, Farrar, William L
Publicado 2011

Promotion of Glioblastoma Cell Motility by Enhancer of Zeste Homolog 2 (EZH2) Is Mediated by AXL Receptor Kinase

por Ott, Martina, Litzenburger, Ulrike M., Sahm, Felix, Rauschenbach, Katharina J., Tudoran, Ruxandra, Hartmann, Christian, Marquez, Victor E., von Deimling, Andreas, Wick, Wolfgang, Platten, Michael
Publicado 2012

EZH2 Down-Regulation Exacerbates Lipid Accumulation and Inflammation in in Vitro and in Vivo NAFLD

por Vella, Serena, Gnani, Daniela, Crudele, Annalisa, Ceccarelli, Sara, De Stefanis, Cristiano, Gaspari, Stefania, Nobili, Valerio, Locatelli, Franco, Marquez, Victor E, Rota, Rossella, Alisi, Anna
Publicado 2013

MicroRNA-26a is Strongly Down-regulated in Melanoma and Induces Cell Death through Repression of Silencer of Death Domains (SODD)

por Reuland, Steven N., Smith, Shilo, Bemis, Lynne, Goldstein, Nathaniel B., Almeida, Adam, Partyka, Katie A, Marquez, Victor E., Zhang, Qinghong, Norris, David A., Shellman, Yiqun G.
Publicado 2012

Conformationally Constrained Analogues of Diacylglycerol (DAG). 31. Modulation of the Biological Properties of Diacylgycerol Lactones (DAG-lactones) Containing Rigid-Rod Acyl Group...

por Comin, Maria J., Czifra, Gabriella, Kedei, Noemi, Telek, Andrea, Lewin, Nancy E., Kolusheva, Sofiya, Velasquez, Julia F., Kobylarz, Ryan, Jelinek, Raz, Blumberg, Peter M., Marquez, Victor E.
Publicado 2009

PRC2 overexpression and PRC2-target gene repression relating to poorer prognosis in small cell lung cancer

por Sato, Teruyuki, Kaneda, Atsushi, Tsuji, Shingo, Isagawa, Takayuki, Yamamoto, Shogo, Fujita, Takanori, Yamanaka, Ryota, Tanaka, Yukiko, Nukiwa, Toshihiro, Marquez, Victor E., Ishikawa, Yuichi, Ichinose, Masakazu, Aburatani, Hiroyuki
Publicado 2013

Derepression of CLDN3 and CLDN4 during ovarian tumorigenesis is associated with loss of repressive histone modifications

por Kwon, Mi Jeong, Kim, Sung-Su, Choi, Yoon-La, Jung, Hun Soon, Balch, Curt, Kim, Su-Hyeong, Song, Yong-Sang, Marquez, Victor E., Nephew, Kenneth P., Shin, Young Kee
Publicado 2010

EZH2 inhibition sensitizes BRG1 and EGFR mutant lung tumors to TopoII inhibitors

por Fillmore, Christine M., Xu, Chunxiao, Desai, Pooja T., Berry, Joanne M., Rowbotham, Samuel P., Lin, Yi-Jang, Zhang, Haikuo, Marquez, Victor E., Hammerman, Peter S., Wong, Kwok-Kin, Kim, Carla F.
Publicado 2015

Epigenetic Analysis of KSHV Latent and Lytic Genomes

por Toth, Zsolt, Maglinte, Dennis T., Lee, Sun Hwa, Lee, Hye-Ra, Wong, Lai-Yee, Brulois, Kevin F., Lee, Stacy, Buckley, Jonathan D., Laird, Peter W., Marquez, Victor E., Jung, Jae U.
Publicado 2010

MicroRNA-101 is repressed by EZH2 and its restoration inhibits tumorigenic features in embryonal rhabdomyosarcoma

por Vella, Serena, Pomella, Silvia, Leoncini, Pier Paolo, Colletti, Marta, Conti, Beatrice, Marquez, Victor E., Strillacci, Antonio, Roma, Josep, Gallego, Soledad, Milano, Giuseppe M., Capogrossi, Maurizio C., Bertaina, Alice, Ciarapica, Roberta, Rota, Rossella
Publicado 2015

Down-Regulation of miR-101 in Endothelial Cells Promotes Blood Vessel Formation through Reduced Repression of EZH2

por Smits, Michiel, Mir, Shahryar E., Nilsson, R. Jonas A., van der Stoop, Petra M., Niers, Johanna M., Marquez, Victor E., Cloos, Jacqueline, Breakefield, Xandra O., Krichevsky, Anna M., Noske, David P., Tannous, Bakhos A., Würdinger, Thomas
Publicado 2011