CRISPR-Cas Immunity against Phages: Its Effects on the Evolution and Survival of Bacterial Pathogens

por Marraffini, Luciano A.
Publicado 2013

Rarely acquired type II-A CRISPR-Cas spacers mediate anti-viral immunity through the targeting of a non-canonical PAM sequence

por Kenney, Claire T, Marraffini, Luciano A
Publicado 2023

Control of gene expression by CRISPR-Cas systems

por Bikard, David, Marraffini, Luciano A.
Publicado 2013

From the discovery of DNA to current tools for DNA editing

por Maguin, Pascal, Marraffini, Luciano A.
Publicado 2021

Self vs. non-self discrimination during CRISPR RNA-directed immunity

por Marraffini, Luciano A., Sontheimer, Erik J.
Publicado 2010

Co-evolution within structured bacterial communities results in multiple expansion of CRISPR loci and enhanced immunity

por Pyenson, Nora C, Marraffini, Luciano A
Publicado 2020

CRISPR-Cas systems exploit viral DNA injection to establish and maintain adaptive immunity

por Modell, Joshua W., Jiang, Wenyan, Marraffini, Luciano A.
Publicado 2017

Cas13-induced cellular dormancy prevents the rise of CRISPR-resistant bacteriophage

por Meeske, Alexander J., Nakandakari-Higa, Sandra, Marraffini, Luciano A.
Publicado 2019

Conditional tolerance of temperate phages via transcription-dependent CRISPR-Cas targeting

por Goldberg, Gregory W., Jiang, Wenyan, Bikard, David, Marraffini, Luciano A.
Publicado 2014

Different modes of spacer acquisition by the Staphylococcus epidermidis type III-A CRISPR-Cas system

por Aviram, Naama, Thornal, Ashley N, Zeevi, David, Marraffini, Luciano A
Publicado 2022

CRISPR-assisted editing of bacterial genomes

por Jiang, Wenyan, Bikard, David, Cox, David, Zhang, Feng, Marraffini, Luciano A.
Publicado 2013

Recombination between phages and CRISPR-cas loci facilitates horizontal gene transfer in staphylococci

por Varble, Andrew, Meaden, Sean, Barrangou, Rodolphe, Westra, Edze R., Marraffini, Luciano A.
Publicado 2019

Programmable repression and activation of bacterial gene expression using an engineered CRISPR-Cas system

por Bikard, David, Jiang, Wenyan, Samai, Poulami, Hochschild, Ann, Zhang, Feng, Marraffini, Luciano A.
Publicado 2013

Dealing with the Evolutionary Downside of CRISPR Immunity: Bacteria and Beneficial Plasmids

por Jiang, Wenyan, Maniv, Inbal, Arain, Fawaz, Wang, Yaying, Levin, Bruce R., Marraffini, Luciano A.
Publicado 2013

A CRISPR-Cas9–integrase complex generates precise DNA fragments for genome integration

por Jakhanwal, Shrutee, Cress, Brady F, Maguin, Pascal, Lobba, Marco J, Marraffini, Luciano A, Doudna, Jennifer A
Publicado 2021

Cas9 specifies functional viral targets during CRISPR-Cas adaptation

por Heler, Robert, Samai, Poulami, Modell, Joshua W., Weiner, Catherine, Goldberg, Gregory W., Bikard, David, Marraffini, Luciano A.
Publicado 2015

The Card1 nuclease provides defence during Type III CRISPR immunity

por Rostøl, Jakob T., Xie, Wei, Kuryavyi, Vitaly, Maguin, Pascal, Kao, Kevin, Froom, Ruby, Patel, Dinshaw J., Marraffini, Luciano A.
Publicado 2021

Incomplete prophage tolerance by type III-A CRISPR-Cas systems reduces the fitness of lysogenic hosts

por Goldberg, Gregory W., McMillan, Elizabeth A., Varble, Andrew, Modell, Joshua W., Samai, Poulami, Jiang, Wenyan, Marraffini, Luciano A.
Publicado 2018

Development of sequence-specific antimicrobials based on programmable CRISPR-Cas nucleases

por Bikard, David, Euler, Chad, Jiang, Wenyan, Nussenzweig, Philip M., Goldberg, Gregory W., Duportet, Xavier, Fischetti, Vincent A., Marraffini, Luciano A.
Publicado 2014

Activation and self-inactivation mechanisms of the cyclic oligoadenylate-dependent CRISPR ribonuclease Csm6

por Garcia-Doval, Carmela, Schwede, Frank, Berk, Christian, Rostøl, Jakob T., Niewoehner, Ole, Tejero, Oliver, Hall, Jonathan, Marraffini, Luciano A., Jinek, Martin
Publicado 2020