CRISPR-Cas Immunity against Phages: Its Effects on the Evolution and Survival of Bacterial Pathogens

by Marraffini, Luciano A.
Published 2013

Rarely acquired type II-A CRISPR-Cas spacers mediate anti-viral immunity through the targeting of a non-canonical PAM sequence

by Kenney, Claire T, Marraffini, Luciano A
Published 2023

Control of gene expression by CRISPR-Cas systems

by Bikard, David, Marraffini, Luciano A.
Published 2013

From the discovery of DNA to current tools for DNA editing

by Maguin, Pascal, Marraffini, Luciano A.
Published 2021

Self vs. non-self discrimination during CRISPR RNA-directed immunity

by Marraffini, Luciano A., Sontheimer, Erik J.
Published 2010

Co-evolution within structured bacterial communities results in multiple expansion of CRISPR loci and enhanced immunity

by Pyenson, Nora C, Marraffini, Luciano A
Published 2020

CRISPR-Cas systems exploit viral DNA injection to establish and maintain adaptive immunity

by Modell, Joshua W., Jiang, Wenyan, Marraffini, Luciano A.
Published 2017

Cas13-induced cellular dormancy prevents the rise of CRISPR-resistant bacteriophage

by Meeske, Alexander J., Nakandakari-Higa, Sandra, Marraffini, Luciano A.
Published 2019

Conditional tolerance of temperate phages via transcription-dependent CRISPR-Cas targeting

by Goldberg, Gregory W., Jiang, Wenyan, Bikard, David, Marraffini, Luciano A.
Published 2014

Different modes of spacer acquisition by the Staphylococcus epidermidis type III-A CRISPR-Cas system

by Aviram, Naama, Thornal, Ashley N, Zeevi, David, Marraffini, Luciano A
Published 2022

CRISPR-assisted editing of bacterial genomes

by Jiang, Wenyan, Bikard, David, Cox, David, Zhang, Feng, Marraffini, Luciano A.
Published 2013

Recombination between phages and CRISPR-cas loci facilitates horizontal gene transfer in staphylococci

by Varble, Andrew, Meaden, Sean, Barrangou, Rodolphe, Westra, Edze R., Marraffini, Luciano A.
Published 2019

Programmable repression and activation of bacterial gene expression using an engineered CRISPR-Cas system

by Bikard, David, Jiang, Wenyan, Samai, Poulami, Hochschild, Ann, Zhang, Feng, Marraffini, Luciano A.
Published 2013

Dealing with the Evolutionary Downside of CRISPR Immunity: Bacteria and Beneficial Plasmids

by Jiang, Wenyan, Maniv, Inbal, Arain, Fawaz, Wang, Yaying, Levin, Bruce R., Marraffini, Luciano A.
Published 2013

A CRISPR-Cas9–integrase complex generates precise DNA fragments for genome integration

by Jakhanwal, Shrutee, Cress, Brady F, Maguin, Pascal, Lobba, Marco J, Marraffini, Luciano A, Doudna, Jennifer A
Published 2021

Cas9 specifies functional viral targets during CRISPR-Cas adaptation

by Heler, Robert, Samai, Poulami, Modell, Joshua W., Weiner, Catherine, Goldberg, Gregory W., Bikard, David, Marraffini, Luciano A.
Published 2015

The Card1 nuclease provides defence during Type III CRISPR immunity

by Rostøl, Jakob T., Xie, Wei, Kuryavyi, Vitaly, Maguin, Pascal, Kao, Kevin, Froom, Ruby, Patel, Dinshaw J., Marraffini, Luciano A.
Published 2021

Incomplete prophage tolerance by type III-A CRISPR-Cas systems reduces the fitness of lysogenic hosts

by Goldberg, Gregory W., McMillan, Elizabeth A., Varble, Andrew, Modell, Joshua W., Samai, Poulami, Jiang, Wenyan, Marraffini, Luciano A.
Published 2018

Development of sequence-specific antimicrobials based on programmable CRISPR-Cas nucleases

by Bikard, David, Euler, Chad, Jiang, Wenyan, Nussenzweig, Philip M., Goldberg, Gregory W., Duportet, Xavier, Fischetti, Vincent A., Marraffini, Luciano A.
Published 2014

Activation and self-inactivation mechanisms of the cyclic oligoadenylate-dependent CRISPR ribonuclease Csm6

by Garcia-Doval, Carmela, Schwede, Frank, Berk, Christian, Rostøl, Jakob T., Niewoehner, Ole, Tejero, Oliver, Hall, Jonathan, Marraffini, Luciano A., Jinek, Martin
Published 2020