Validation of ultrasound bioimaging to predict worm burden and treatment efficacy in preclinical filariasis drug screening models

por Marriott, Amy E., Sjoberg, Hanna, Tyrer, Hayley, Gamble, Joanne, Murphy, Emma, Archer, John, Steven, Andrew, Taylor, Mark J., Turner, Joseph D.
Publicado 2018

A mouse infection model and long-term lymphatic endothelium co-culture system to evaluate drugs against adult Brugia malayi

por Marriott, Amy E., Furlong Silva, Julio, Pionnier, Nicolas, Sjoberg, Hanna, Archer, John, Steven, Andrew, Kempf, Dale, Taylor, Mark J., Turner, Joseph D.
Publicado 2022

Tetracyclines improve experimental lymphatic filariasis pathology by disrupting interleukin-4 receptor–mediated lymphangiogenesis

por Furlong-Silva, Julio, Cross, Stephen D., Marriott, Amy E., Pionnier, Nicolas, Archer, John, Steven, Andrew, Merker, Stefan Schulte, Mack, Matthias, Hong, Young-Kwon, Taylor, Mark J., Turner, Joseph D.
Publicado 2021

In vitro and in vivo preclinical venom inhibition assays identify metalloproteinase inhibiting drugs as potential future treatments for snakebite envenoming by Dispholidus typus

por Menzies, Stefanie K., Clare, Rachel H., Xie, Chunfang, Westhorpe, Adam, Hall, Steven R., Edge, Rebecca J., Alsolaiss, Jaffer, Crittenden, Edouard, Marriott, Amy E., Harrison, Robert A., Kool, Jeroen, Casewell, Nicholas R.
Publicado 2022

NKp46(+) natural killer cells develop an activated/memory-like phenotype and contribute to innate immunity against experimental filarial infection

por Pionnier, Nicolas, Furlong-Silva, Julio, Colombo, Stefano A. P., Marriott, Amy E., Chunda, Valerine C., Ndzeshang, Bertrand L., Sjoberg, Hanna, Archer, John, Steven, Andrew, Wanji, Samuel, Taylor, Mark J., Turner, Joseph D.
Publicado 2022

Wolbachia depletion blocks transmission of lymphatic filariasis by preventing chitinase-dependent parasite exsheathment

por Quek, Shannon, Cook, Darren A. N., Wu, Yang, Marriott, Amy E., Steven, Andrew, Johnston, Kelly L., Ford, Louise, Archer, John, Hemingway, Janet, Ward, Stephen A., Wagstaff, Simon C., Turner, Joseph D., Taylor, Mark J.
Publicado 2022

Structural Requirements for Dihydrobenzoxazepinone Anthelmintics: Actions against Medically Important and Model Parasites: Trichuris muris, Brugia malayi, Heligmosomoides polygyrus...

por Partridge, Frederick A., Bataille, Carole J.R., Forman, Ruth, Marriott, Amy E., Forde-Thomas, Josephine, Häberli, Cécile, Dinsdale, Ria L., O’Sullivan, James D.B., Willis, Nicky J., Wynne, Graham M., Whiteland, Helen, Archer, John, Steven, Andrew, Keiser, Jennifer, Turner, Joseph D., Hoffmann, Karl F., Taylor, Mark J., Else, Kathryn J., Russell, Angela J., Sattelle, David B.
Publicado 2021