Divergent Roles for TRAIL in Lung Diseases

por Braithwaite, Adam T., Marriott, Helen M., Lawrie, Allan
Publicado 2018

A mathematical model shows macrophages delay Staphylococcus aureus replication, but limitations in microbicidal capacity restrict bacterial clearance

por Best, Alex, Jubrail, Jamil, Boots, Mike, Dockrell, David, Marriott, Helen
Publicado 2020

Liposomal Co-Entrapment of CD40mAb Induces Enhanced IgG Responses against Bacterial Polysaccharide and Protein

por Hatzifoti, Caterina, Bacon, Andrew, Marriott, Helen, Laing, Peter, Heath, Andrew W.
Publicado 2008

The Identification of Markers of Macrophage Differentiation in PMA-Stimulated THP-1 Cells and Monocyte-Derived Macrophages

por Daigneault, Marc, Preston, Julie A., Marriott, Helen M., Whyte, Moira K. B., Dockrell, David H.
Publicado 2010

Differential localisation of BPIFA1 (SPLUNC1) and BPIFB1 (LPLUNC1) in the nasal and oral cavities of mice

por Musa, Maslinda, Wilson, Kirsty, Sun, Le, Mulay, Apoorva, Bingle, Lynne, Marriott, Helen M., LeClair, Elizabeth E., Bingle, Colin D.
Publicado 2012

TNF-related apoptosis-inducing ligand (TRAIL) regulates inflammatory neutrophil apoptosis and enhances resolution of inflammation

por McGrath, Emmet E., Marriott, Helen M., Lawrie, Allan, Francis, Sheila E., Sabroe, Ian, Renshaw, Stephen A., Dockrell, David H., Whyte, Moira K. B.
Publicado 2011

The EGFR/ErbB inhibitor neratinib modifies the neutrophil phosphoproteome and promotes apoptosis and clearance by airway macrophages

por Herman, Kimberly D., Wright, Carl G., Marriott, Helen M., McCaughran, Sam C., Bowden, Kieran A., Collins, Mark O., Renshaw, Stephen A., Prince, Lynne R.
Publicado 2022

Transient increase in atherosclerotic plaque macrophage content following Streptococcus pneumoniae pneumonia in ApoE-deficient mice

por Bazaz, Rohit, Marriott, Helen M., Wright, Carl, Chamberlain, Janet, West, Laura E., Gelsthorpe, Catherine, Heath, Paul R., Maleki-Dizaji, Afsaneh, Francis, Sheila E., Dockrell, David H.
Publicado 2023

Pneumolysin Activates Macrophage Lysosomal Membrane Permeabilization and Executes Apoptosis by Distinct Mechanisms without Membrane Pore Formation

por Bewley, Martin A., Naughton, Michael, Preston, Julie, Mitchell, Andrea, Holmes, Ashleigh, Marriott, Helen M., Read, Robert C., Mitchell, Timothy J., Whyte, Moira K. B., Dockrell, David H.
Publicado 2014

Inability to sustain intraphagolysosomal killing of Staphylococcus aureus predisposes to bacterial persistence in macrophages

por Jubrail, Jamil, Morris, Paul, Bewley, Martin A., Stoneham, Simon, Johnston, Simon A., Foster, Simon J., Peden, Andrew A., Read, Robert C., Marriott, Helen M., Dockrell, David H.
Publicado 2015

A Cardinal Role for Cathepsin D in Co-Ordinating the Host-Mediated Apoptosis of Macrophages and Killing of Pneumococci

por Bewley, Martin A., Marriott, Helen M., Tulone, Calogero, Francis, Sheila E., Mitchell, Timothy J., Read, Robert C., Chain, Benny, Kroemer, Guido, Whyte, Moira K. B., Dockrell, David H.
Publicado 2011

Monocytes Regulate the Mechanism of T-cell Death by Inducing Fas-Mediated Apoptosis during Bacterial Infection

por Daigneault, Marc, De Silva, Thushan I., Bewley, Martin A., Preston, Julie A., Marriott, Helen M., Mitchell, Andrea M., Mitchell, Timothy J., Read, Robert C., Whyte, Moira K. B., Dockrell, David H.
Publicado 2012

A decoy receptor 3 analogue reduces localised defects in phagocyte function in pneumococcal pneumonia

por Marriott, Helen M, Daigneault, Marc, Thompson, Alfred A R, Walmsley, Sarah R, Gill, Sharonjit K, Witcher, Derrick R, Wroblewski, Victor J, Hellewell, Paul G, Whyte, Moira K B, Dockrell, David H
Publicado 2012

Proteomic Evaluation and Validation of Cathepsin D Regulated Proteins in Macrophages Exposed to Streptococcus pneumoniae

por Bewley, Martin A., Pham, Trong K., Marriott, Helen M., Noirel, Josselin, Chu, Hseuh-Ping, Ow, Saw Y., Ryazanov, Alexey G., Read, Robert C., Whyte, Moira K. B., Chain, Benny, Wright, Phillip C., Dockrell, David H.
Publicado 2011

Pellino-1 Regulates Immune Responses to Haemophilus influenzae in Models of Inflammatory Lung Disease

por Hughes, Bethany M., Burton, Charlotte S., Reese, Abigail, Jabeen, Maisha F., Wright, Carl, Willis, Jessica, Khoshaein, Nika, Marsh, Elizabeth K., Peachell, Peter, Sun, Shao C., Dockrell, David H., Marriott, Helen M., Sabroe, Ian, Condliffe, Alison M., Prince, Lynne R.
Publicado 2019

Deficiency of tumour necrosis factor-related apoptosis-inducing ligand exacerbates lung injury and fibrosis

por McGrath, Emmet E, Lawrie, Allan, Marriott, Helen M, Mercer, Paul, Cross, Simon S, Arnold, Nadine, Singleton, Vanessa, Thompson, Alfred A R, Walmsley, Sarah R, Renshaw, Stephen A, Sabroe, Ian, Chambers, Rachel C, Dockrell, David H, Whyte, Moira K B
Publicado 2012

Pellino-1 Regulates the Responses of the Airway to Viral Infection

por Marsh, Elizabeth K., Prestwich, Elizabeth C., Williams, Lynne, Hart, Amber R., Muir, Clare F., Parker, Lisa C., Jonker, Marnix R., Heijink, Irene H., Timens, Wim, Fife, Mark, Hussell, Tracy, Hershenson, Marc B., Bentley, J. Kelley, Sun, Shao-Cong, Barksby, Ben S., Borthwick, Lee A., Stewart, James P., Sabroe, Ian, Dockrell, David H., Marriott, Helen M.
Publicado 2020

RIPOSTE: a framework for improving the design and analysis of laboratory-based research

por Masca, Nicholas GD, Hensor, Elizabeth MA, Cornelius, Victoria R, Buffa, Francesca M, Marriott, Helen M, Eales, James M, Messenger, Michael P, Anderson, Amy E, Boot, Chris, Bunce, Catey, Goldin, Robert D, Harris, Jessica, Hinchliffe, Rod F, Junaid, Hiba, Kingston, Shaun, Martin-Ruiz, Carmen, Nelson, Christopher P, Peacock, Janet, Seed, Paul T, Shinkins, Bethany, Staples, Karl J, Toombs, Jamie, Wright, Adam KA, Teare, M Dawn
Publicado 2015

Prolyl hydroxylase 2 inactivation enhances glycogen storage and promotes excessive neutrophilic responses

por Sadiku, Pranvera, Willson, Joseph A., Dickinson, Rebecca S., Murphy, Fiona, Harris, Alison J., Lewis, Amy, Sammut, David, Mirchandani, Ananda S., Ryan, Eilise, Watts, Emily R., Thompson, A.A. Roger, Marriott, Helen M., Dockrell, David H., Taylor, Cormac T., Schneider, Martin, Maxwell, Patrick H., Chilvers, Edwin R., Mazzone, Massimilliano, Moral, Veronica, Pugh, Chris W., Ratcliffe, Peter J., Schofield, Christopher J., Ghesquiere, Bart, Carmeliet, Peter, Whyte, Moira K.B., Walmsley, Sarah R.
Publicado 2017