GPCR homo-oligomerization

por Milligan, Graeme, Ward, Richard J, Marsango, Sara
Publicado 2019

Distinct Agonist Regulation of Muscarinic Acetylcholine M(2)-M(3) Heteromers and Their Corresponding Homomers

por Aslanoglou, Despoina, Alvarez-Curto, Elisa, Marsango, Sara, Milligan, Graeme
Publicado 2015

Spatial Intensity Distribution Analysis: Studies of G Protein-Coupled Receptor Oligomerisation

por Pediani, John D., Ward, Richard J., Marsango, Sara, Milligan, Graeme
Publicado 2018

Muscarinic receptor oligomerization

por Marsango, Sara, Ward, Richard J., Alvarez-Curto, Elisa, Milligan, Graeme
Publicado 2018

Therapeutic validation of an orphan G protein‐coupled receptor: The case of GPR84

por Marsango, Sara, Barki, Natasja, Jenkins, Laura, Tobin, Andrew B., Milligan, Graeme
Publicado 2020

Analysis of Human Dopamine D(3) Receptor Quaternary Structure

por Marsango, Sara, Caltabiano, Gianluigi, Pou, Chantevy, Varela Liste, María José, Milligan, Graeme
Publicado 2015

Dynamic Regulation of Quaternary Organization of the M(1) Muscarinic Receptor by Subtype-selective Antagonist Drugs

por Pediani, John D., Ward, Richard J., Godin, Antoine G., Marsango, Sara, Milligan, Graeme
Publicado 2016

Defining the organizational structure of dopamine and muscarninic acetylcholine receptors

por Milligan, Graeme, Liste, María José Varela, Caltabiano, Gianluigi Caltabiano, Alvarez-Curto, Elisa, Marsango, Sara
Publicado 2015

A Molecular Basis for Selective Antagonist Destabilization of Dopamine D(3) Receptor Quaternary Organization

por Marsango, Sara, Caltabiano, Gianluigi, Jiménez-Rosés, Mireia, Millan, Mark J., Pediani, John D., Ward, Richard J., Milligan, Graeme
Publicado 2017

Chemokine receptor CXCR4 oligomerization is disrupted selectively by the antagonist ligand IT1t

por Ward, Richard J., Pediani, John D., Marsango, Sara, Jolly, Richard, Stoneman, Michael R., Biener, Gabriel, Handel, Tracy M., Raicu, Valerică, Milligan, Graeme
Publicado 2020

Selective phosphorylation of threonine residues defines GPR84–arrestin interactions of biased ligands

por Marsango, Sara, Ward, Richard J., Jenkins, Laura, Butcher, Adrian J., Al Mahmud, Zobaer, Dwomoh, Louis, Nagel, Falko, Schulz, Stefan, Tikhonova, Irina G., Tobin, Andrew B., Milligan, Graeme
Publicado 2022

The M(1) muscarinic receptor is present in situ as a ligand-regulated mixture of monomers and oligomeric complexes

por Marsango, Sara, Jenkins, Laura, Pediani, John D., Bradley, Sophie J., Ward, Richard J., Hesse, Sarah, Biener, Gabriel, Stoneman, Michael R., Tobin, Andrew B., Raicu, Valerica, Milligan, Graeme
Publicado 2022

Discovery and Characterization of Novel Antagonists of the Proinflammatory Orphan Receptor GPR84

por Jenkins, Laura, Marsango, Sara, Mancini, Sarah, Mahmud, Zobaer Al, Morrison, Angus, McElroy, Stuart P., Bennett, Kirstie A., Barnes, Matt, Tobin, Andrew B., Tikhonova, Irina G., Milligan, Graeme
Publicado 2021

Investigating the Structure–Activity Relationship of 1,2,4-Triazine G-Protein-Coupled Receptor 84 (GPR84) Antagonists

por Mahindra, Amit, Jenkins, Laura, Marsango, Sara, Huggett, Mark, Huggett, Margaret, Robinson, Lindsay, Gillespie, Jonathan, Rajamanickam, Muralikrishnan, Morrison, Angus, McElroy, Stuart, Tikhonova, Irina G., Milligan, Graeme, Jamieson, Andrew G.
Publicado 2022

Pro-phagocytic function and structural basis of GPR84 signaling

por Zhang, Xuan, Wang, Yujing, Supekar, Shreyas, Cao, Xu, Zhou, Jingkai, Dang, Jessica, Chen, Siqi, Jenkins, Laura, Marsango, Sara, Li, Xiu, Liu, Guibing, Milligan, Graeme, Feng, Mingye, Fan, Hao, Gong, Weimin, Zhang, Cheng
Publicado 2023

Pro-phagocytic function and structural basis of GPR84 signaling

por Zhang, Xuan, Wang, Yujing, Supekar, Shreyas, Cao, Xu, Zhou, Jingkai, Dang, Jessica, Chen, Siqi, Jenkins, Laura, Marsango, Sara, Li, Xiu, Liu, Guibing, Milligan, Graeme, Feng, Mingye, Fan, Hao, Gong, Weimin, Zhang, Cheng
Publicado 2023

Biased M1 muscarinic receptor mutant mice show accelerated progression of prion neurodegenerative disease

por Scarpa, Miriam, Molloy, Colin, Jenkins, Laura, Strellis, Bethany, Budgett, Rebecca F., Hesse, Sarah, Dwomoh, Louis, Marsango, Sara, Tejeda, Gonzalo S., Rossi, Mario, Ahmed, Zeshan, Milligan, Graeme, Hudson, Brian D., Tobin, Andrew B., Bradley, Sophie J.
Publicado 2021