Tumour-agnostic drugs in paediatric cancers

por Chisholm, Julia C., Carceller, Fernando, Marshall, Lynley V.
Publicado 2020

Reply to ‘Comment on “Tumour-agnostic drugs in paediatric cancers”’

por Chisholm, Julia C., Carceller, Fernando, Marshall, Lynley V.
Publicado 2020

Liquid biopsy for children with central nervous system tumours: Clinical integration and technical considerations

por Stankunaite, Reda, Marshall, Lynley V., Carceller, Fernando, Chesler, Louis, Hubank, Michael, George, Sally L.
Publicado 2022

Novel therapeutic approaches for pediatric diencephalic tumors: improving functional outcomes

por Cockle, Julia V., Corley, Elizabeth A., Zebian, Bassel, Hettige, Samantha, Vaidya, Sucheta J., Angelini, Paola, Stone, Joanna, Leitch, R Jane, Albanese, Assunta, Mandeville, Henry C., Carceller, Fernando, Marshall, Lynley V.
Publicado 2023

In vitro nuclear magnetic resonance spectroscopy metabolic biomarkers for the combination of temozolomide with PI3K inhibition in paediatric glioblastoma cells

por Al-Saffar, Nada M. S., Agliano, Alice, Marshall, Lynley V., Jackson, L. Elizabeth, Balarajah, Geetha, Sidhu, Jasmin, Clarke, Paul A., Jones, Chris, Workman, Paul, Pearson, Andrew D. J., Leach, Martin O.
Publicado 2017

Lactate and Choline Metabolites Detected In Vitro by Nuclear Magnetic Resonance Spectroscopy Are Potential Metabolic Biomarkers for PI3K Inhibition in Pediatric Glioblastoma

por Al-Saffar, Nada M. S., Marshall, Lynley V., Jackson, L. Elizabeth, Balarajah, Geetha, Eykyn, Thomas R., Agliano, Alice, Clarke, Paul A., Jones, Chris, Workman, Paul, Pearson, Andrew D. J., Leach, Martin O.
Publicado 2014

Multimodal immunogenomic biomarker analysis of tumors from pediatric patients enrolled to a phase 1-2 study of single-agent atezolizumab

por Nabbi, Arash, Danesh, Arnavaz, Espin-Garcia, Osvaldo, Pedersen, Stephanie, Wellum, Johanna, Fu, Lingyan Helen, Paulson, Joseph N., Geoerger, Birgit, Marshall, Lynley V., Trippett, Tanya, Rossato, Gianluca, Pugh, Trevor J., Hutchinson, Katherine E.
Publicado 2023

Regorafenib plus Vincristine and Irinotecan in Pediatric Patients with Recurrent/Refractory Solid Tumors: An Innovative Therapy for Children with Cancer Study

por Casanova, Michela, Bautista, Francisco, Campbell-Hewson, Quentin, Makin, Guy, Marshall, Lynley V., Verschuur, Arnauld C., Cañete Nieto, Adela, Corradini, Nadège, Ploeger, Bart A., Brennan, Barbara J., Mueller, Udo, Zebger-Gong, Hong, Chung, John W., Geoerger, Birgit
Publicado 2023

Demonstration of the reproducibility of free-breathing diffusion-weighted MRI and dynamic contrast enhanced MRI in children with solid tumours: a pilot study

por Miyazaki, Keiko, Jerome, Neil P., Collins, David J., Orton, Matthew R., d’Arcy, James A., Wallace, Toni, Moreno, Lucas, Pearson, Andrew D. J., Marshall, Lynley V., Carceller, Fernando, Leach, Martin O., Zacharoulis, Stergios, Koh, Dow-Mu
Publicado 2015

Repeatability of derived parameters from histograms following non-Gaussian diffusion modelling of diffusion-weighted imaging in a paediatric oncological cohort

por Jerome, Neil P., Miyazaki, Keiko, Collins, David J., Orton, Matthew R., d’Arcy, James A., Wallace, Toni, Moreno, Lucas, Pearson, Andrew D. J., Marshall, Lynley V., Carceller, Fernando, Leach, Martin O., Zacharoulis, Stergios, Koh, Dow-Mu
Publicado 2016

Phase 2 Study of Pomalidomide (CC-4047) Monotherapy for Children and Young Adults With Recurrent or Progressive Primary Brain Tumors

por Fangusaro, Jason, Cefalo, Maria Giuseppina, Garré, Maria Luisa, Marshall, Lynley V., Massimino, Maura, Benettaib, Bouchra, Biserna, Noha, Poon, Jennifer, Quan, Jackie, Conlin, Erin, Lewandowski, John, Simcock, Mathew, Jeste, Neelum, Hargrave, Darren R., Doz, François, Warren, Katherine E.
Publicado 2021

Molecular and Phenotypic Characterisation of Paediatric Glioma Cell Lines as Models for Preclinical Drug Development

por Bax, Dorine A., Little, Suzanne E., Gaspar, Nathalie, Perryman, Lara, Marshall, Lynley, Viana-Pereira, Marta, Jones, Tania A., Williams, Richard D., Grigoriadis, Anita, Vassal, Gilles, Workman, Paul, Sheer, Denise, Reis, Rui M., Pearson, Andrew D. J., Hargrave, Darren, Jones, Chris
Publicado 2009

HGG-15. HIGH-GRADE GLIOMAS OCCURRING IN TEENAGERS AND YOUNG ADULT PATIENTS COMPRISE NOVEL MOLECULAR SUBGROUPS

por Clarke, Matthew, Pereira, Rita, Mackay, Alan, Grabovska, Yura, Clarke, Amelia, Nicoll, James, Procter, John, Moore, Andrew, Schagen, Joanna, Walker, Liam, Roncaroli, Federico, Ogunbigi, Olumide, Jacques, Thomas, Marshall, Lynley, Carceller, Fernando, Reisz, Zita, Al-Sarraj, Safa, Vinci, Maria, Kurian, Kathreena, Ng, H K, Brandner, Sebastian, Jones, Chris
Publicado 2023

Droplet digital PCR-based detection of circulating tumor DNA from pediatric high grade and diffuse midline glioma patients

por Izquierdo, Elisa, Proszek, Paula, Pericoli, Giulia, Temelso, Sara, Clarke, Matthew, Carvalho, Diana M, Mackay, Alan, Marshall, Lynley V, Carceller, Fernando, Hargrave, Darren, Lannering, Birgitta, Pavelka, Zdenek, Bailey, Simon, Entz-Werle, Natacha, Grill, Jacques, Vassal, Gilles, Rodriguez, Daniel, Morgan, Paul S, Jaspan, Tim, Mastronuzzi, Angela, Vinci, Mara, Hubank, Michael, Jones, Chris
Publicado 2021

MODL-20. A BIOBANK OF ~100 PATIENT-DERIVED MODELS REPRESENTING BIOLOGICAL HETEROGENEITY AND DISTINCT THERAPEUTIC DEPENDENCIES IN PAEDIATRIC HIGH GRADE GLIOMA AND DIPG

por Carvalho, Diana, Mackay, Alan, Temelso, Sara, Izquierdo, Elisa, Fernandez, Elisabet Potente, Rogers, Rebecca, Boult, Jessica, Salom, Janat Fazal, Simon, Natalie, Clarke, Matthew, Molinari, Valeria, Kessler, Ketty, Burford, Anna, Bjerke, Lynn, Fofana, Mariama, Hubank, Michael, Pears, Jane, Moore, Andrew, Carcaboso, Angel Montero, Marshall, Lynley, Carceller, Fernando, Robinson, Simon, Hargrave, Darren, Vinci, Maria, Jones, Chris
Publicado 2020

Development of a targeted sequencing approach to identify prognostic, predictive and diagnostic markers in paediatric solid tumours

por Izquierdo, Elisa, Yuan, Lina, George, Sally, Hubank, Michael, Jones, Chris, Proszek, Paula, Shipley, Janet, Gatz, Susanne A., Stinson, Caedyn, Moore, Andrew S., Clifford, Steven C., Hicks, Debbie, Lindsey, Janet C., Hill, Rebecca M., Jacques, Thomas S., Chalker, Jane, Thway, Khin, O’Connor, Simon, Marshall, Lynley, Moreno, Lucas, Pearson, Andrew, Chesler, Louis, Walker, Brian A., De Castro, David Gonzalez
Publicado 2017

Entrectinib in children and young adults with solid or primary CNS tumors harboring NTRK, ROS1, or ALK aberrations (STARTRK-NG)

por Desai, Ami V, Robinson, Giles W, Gauvain, Karen, Basu, Ellen M, Macy, Margaret E, Maese, Luke, Whipple, Nicholas S, Sabnis, Amit J, Foster, Jennifer H, Shusterman, Suzanne, Yoon, Janet, Weiss, Brian D, Abdelbaki, Mohamed S, Armstrong, Amy E, Cash, Thomas, Pratilas, Christine A, Corradini, Nadège, Marshall, Lynley V, Farid-Kapadia, Mufiza, Chohan, Saibah, Devlin, Clare, Meneses-Lorente, Georgina, Cardenas, Alison, Hutchinson, Katherine E, Bergthold, Guillaume, Caron, Hubert, Chow Maneval, Edna, Gajjar, Amar, Fox, Elizabeth
Publicado 2022

Enhancing reporting quality and impact of early phase dose-finding clinical trials: CONSORT Dose-finding Extension (CONSORT-DEFINE) guidance

por Yap, Christina, Solovyeva, Olga, de Bono, Johann, Rekowski, Jan, Patel, Dhrusti, Jaki, Thomas, Mander, Adrian, Evans, Thomas R Jeffry, Peck, Richard, Hayward, Kathryn S, Hopewell, Sally, Ursino, Moreno, Rantell, Khadija Rerhou, Calvert, Melanie, Lee, Shing, Kightley, Andrew, Ashby, Deborah, Chan, An-Wen, Garrett-Mayer, Elizabeth, Isaacs, John D, Golub, Robert, Kholmanskikh, Olga, Richards, Dawn, Boix, Oliver, Matcham, James, Seymour, Lesley, Ivy, S Percy, Marshall, Lynley V, Hommais, Antoine, Liu, Rong, Tanaka, Yoshiya, Berlin, Jordan, Espinasse, Aude, Dimairo, Munyaradzi, Weir, Christopher J
Publicado 2023

A tailored molecular profiling programme for children with cancer to identify clinically actionable genetic alterations

por George, Sally L., Izquierdo, Elisa, Campbell, James, Koutroumanidou, Eleni, Proszek, Paula, Jamal, Sabri, Hughes, Deborah, Yuan, Lina, Marshall, Lynley V., Carceller, Fernando, Chisholm, Julia C., Vaidya, Sucheta, Mandeville, Henry, Angelini, Paola, Wasti, Ajla, Bexelius, Tomas, Thway, Khin, Gatz, Susanne A., Clarke, Matthew, Al-Lazikani, Bissan, Barone, Giuseppe, Anderson, John, Tweddle, Deborah A., Gonzalez, David, Walker, Brian A., Barton, Jack, Depani, Sarita, Eze, Jessica, Ahmed, Saira W., Moreno, Lucas, Pearson, Andrew, Shipley, Janet, Jones, Chris, Hargrave, Darren, Jacques, Thomas S., Hubank, Michael, Chesler, Louis
Publicado 2019

Impact of COVID-19 in paediatric early-phase cancer clinical trials in Europe: A report from the Innovative Therapies for Children with Cancer (ITCC) consortium

por Rubio-San-Simón, Alba, André, Nicolas, Cefalo, Maria Giuseppina, Aerts, Isabelle, Castañeda, Alicia, Benezech, Sarah, Makin, Guy, van Eijkelenburg, Natasha, Nysom, Karsten, Marshall, Lynley, Gambart, Marion, Hladun, Raquel, Rossig, Claudia, Bergamaschi, Luca, Fagioli, Franca, Carpenter, Ben, Ducassou, Stephane, Owens, Cormac, Øra, Ingrid, Ribelles, Antonio Juan, De Wilde, Bram, Guerra-García, Pilar, Strullu, Marion, Rizzari, Carmelo, Ek, Torben, Hettmer, Simone, Gerber, Nicolas U., Rawlings, Christine, Diezi, Manuel, Palmu, Sauli, Ruggiero, Antonio, Verdú, Jaime, de Rojas, Teresa, Vassal, Gilles, Geoerger, Birgit, Moreno, Lucas, Bautista, Francisco
Publicado 2020