Tumour-agnostic drugs in paediatric cancers

por Chisholm, Julia C., Carceller, Fernando, Marshall, Lynley V.
Publicado 2020

Reply to ‘Comment on “Tumour-agnostic drugs in paediatric cancers”’

por Chisholm, Julia C., Carceller, Fernando, Marshall, Lynley V.
Publicado 2020

Liquid biopsy for children with central nervous system tumours: Clinical integration and technical considerations

por Stankunaite, Reda, Marshall, Lynley V., Carceller, Fernando, Chesler, Louis, Hubank, Michael, George, Sally L.
Publicado 2022

Novel therapeutic approaches for pediatric diencephalic tumors: improving functional outcomes

por Cockle, Julia V., Corley, Elizabeth A., Zebian, Bassel, Hettige, Samantha, Vaidya, Sucheta J., Angelini, Paola, Stone, Joanna, Leitch, R Jane, Albanese, Assunta, Mandeville, Henry C., Carceller, Fernando, Marshall, Lynley V.
Publicado 2023

In vitro nuclear magnetic resonance spectroscopy metabolic biomarkers for the combination of temozolomide with PI3K inhibition in paediatric glioblastoma cells

por Al-Saffar, Nada M. S., Agliano, Alice, Marshall, Lynley V., Jackson, L. Elizabeth, Balarajah, Geetha, Sidhu, Jasmin, Clarke, Paul A., Jones, Chris, Workman, Paul, Pearson, Andrew D. J., Leach, Martin O.
Publicado 2017

Lactate and Choline Metabolites Detected In Vitro by Nuclear Magnetic Resonance Spectroscopy Are Potential Metabolic Biomarkers for PI3K Inhibition in Pediatric Glioblastoma

por Al-Saffar, Nada M. S., Marshall, Lynley V., Jackson, L. Elizabeth, Balarajah, Geetha, Eykyn, Thomas R., Agliano, Alice, Clarke, Paul A., Jones, Chris, Workman, Paul, Pearson, Andrew D. J., Leach, Martin O.
Publicado 2014

Multimodal immunogenomic biomarker analysis of tumors from pediatric patients enrolled to a phase 1-2 study of single-agent atezolizumab

por Nabbi, Arash, Danesh, Arnavaz, Espin-Garcia, Osvaldo, Pedersen, Stephanie, Wellum, Johanna, Fu, Lingyan Helen, Paulson, Joseph N., Geoerger, Birgit, Marshall, Lynley V., Trippett, Tanya, Rossato, Gianluca, Pugh, Trevor J., Hutchinson, Katherine E.
Publicado 2023

Regorafenib plus Vincristine and Irinotecan in Pediatric Patients with Recurrent/Refractory Solid Tumors: An Innovative Therapy for Children with Cancer Study

por Casanova, Michela, Bautista, Francisco, Campbell-Hewson, Quentin, Makin, Guy, Marshall, Lynley V., Verschuur, Arnauld C., Cañete Nieto, Adela, Corradini, Nadège, Ploeger, Bart A., Brennan, Barbara J., Mueller, Udo, Zebger-Gong, Hong, Chung, John W., Geoerger, Birgit
Publicado 2023

Demonstration of the reproducibility of free-breathing diffusion-weighted MRI and dynamic contrast enhanced MRI in children with solid tumours: a pilot study

por Miyazaki, Keiko, Jerome, Neil P., Collins, David J., Orton, Matthew R., d’Arcy, James A., Wallace, Toni, Moreno, Lucas, Pearson, Andrew D. J., Marshall, Lynley V., Carceller, Fernando, Leach, Martin O., Zacharoulis, Stergios, Koh, Dow-Mu
Publicado 2015

Repeatability of derived parameters from histograms following non-Gaussian diffusion modelling of diffusion-weighted imaging in a paediatric oncological cohort

por Jerome, Neil P., Miyazaki, Keiko, Collins, David J., Orton, Matthew R., d’Arcy, James A., Wallace, Toni, Moreno, Lucas, Pearson, Andrew D. J., Marshall, Lynley V., Carceller, Fernando, Leach, Martin O., Zacharoulis, Stergios, Koh, Dow-Mu
Publicado 2016

Phase 2 Study of Pomalidomide (CC-4047) Monotherapy for Children and Young Adults With Recurrent or Progressive Primary Brain Tumors

por Fangusaro, Jason, Cefalo, Maria Giuseppina, Garré, Maria Luisa, Marshall, Lynley V., Massimino, Maura, Benettaib, Bouchra, Biserna, Noha, Poon, Jennifer, Quan, Jackie, Conlin, Erin, Lewandowski, John, Simcock, Mathew, Jeste, Neelum, Hargrave, Darren R., Doz, François, Warren, Katherine E.
Publicado 2021

Droplet digital PCR-based detection of circulating tumor DNA from pediatric high grade and diffuse midline glioma patients

por Izquierdo, Elisa, Proszek, Paula, Pericoli, Giulia, Temelso, Sara, Clarke, Matthew, Carvalho, Diana M, Mackay, Alan, Marshall, Lynley V, Carceller, Fernando, Hargrave, Darren, Lannering, Birgitta, Pavelka, Zdenek, Bailey, Simon, Entz-Werle, Natacha, Grill, Jacques, Vassal, Gilles, Rodriguez, Daniel, Morgan, Paul S, Jaspan, Tim, Mastronuzzi, Angela, Vinci, Mara, Hubank, Michael, Jones, Chris
Publicado 2021

Entrectinib in children and young adults with solid or primary CNS tumors harboring NTRK, ROS1, or ALK aberrations (STARTRK-NG)

por Desai, Ami V, Robinson, Giles W, Gauvain, Karen, Basu, Ellen M, Macy, Margaret E, Maese, Luke, Whipple, Nicholas S, Sabnis, Amit J, Foster, Jennifer H, Shusterman, Suzanne, Yoon, Janet, Weiss, Brian D, Abdelbaki, Mohamed S, Armstrong, Amy E, Cash, Thomas, Pratilas, Christine A, Corradini, Nadège, Marshall, Lynley V, Farid-Kapadia, Mufiza, Chohan, Saibah, Devlin, Clare, Meneses-Lorente, Georgina, Cardenas, Alison, Hutchinson, Katherine E, Bergthold, Guillaume, Caron, Hubert, Chow Maneval, Edna, Gajjar, Amar, Fox, Elizabeth
Publicado 2022

Enhancing reporting quality and impact of early phase dose-finding clinical trials: CONSORT Dose-finding Extension (CONSORT-DEFINE) guidance

por Yap, Christina, Solovyeva, Olga, de Bono, Johann, Rekowski, Jan, Patel, Dhrusti, Jaki, Thomas, Mander, Adrian, Evans, Thomas R Jeffry, Peck, Richard, Hayward, Kathryn S, Hopewell, Sally, Ursino, Moreno, Rantell, Khadija Rerhou, Calvert, Melanie, Lee, Shing, Kightley, Andrew, Ashby, Deborah, Chan, An-Wen, Garrett-Mayer, Elizabeth, Isaacs, John D, Golub, Robert, Kholmanskikh, Olga, Richards, Dawn, Boix, Oliver, Matcham, James, Seymour, Lesley, Ivy, S Percy, Marshall, Lynley V, Hommais, Antoine, Liu, Rong, Tanaka, Yoshiya, Berlin, Jordan, Espinasse, Aude, Dimairo, Munyaradzi, Weir, Christopher J
Publicado 2023

A tailored molecular profiling programme for children with cancer to identify clinically actionable genetic alterations

por George, Sally L., Izquierdo, Elisa, Campbell, James, Koutroumanidou, Eleni, Proszek, Paula, Jamal, Sabri, Hughes, Deborah, Yuan, Lina, Marshall, Lynley V., Carceller, Fernando, Chisholm, Julia C., Vaidya, Sucheta, Mandeville, Henry, Angelini, Paola, Wasti, Ajla, Bexelius, Tomas, Thway, Khin, Gatz, Susanne A., Clarke, Matthew, Al-Lazikani, Bissan, Barone, Giuseppe, Anderson, John, Tweddle, Deborah A., Gonzalez, David, Walker, Brian A., Barton, Jack, Depani, Sarita, Eze, Jessica, Ahmed, Saira W., Moreno, Lucas, Pearson, Andrew, Shipley, Janet, Jones, Chris, Hargrave, Darren, Jacques, Thomas S., Hubank, Michael, Chesler, Louis
Publicado 2019

Functional diversity and co-operativity between subclonal populations of paediatric glioblastoma and diffuse intrinsic pontine glioma cells

por Vinci, Mara, Burford, Anna, Molinari, Valeria, Kessler, Ketty, Popov, Sergey, Clarke, Matthew, Taylor, Kathryn R, Pemberton, Helen, Lord, Christopher J, Gutteridge, Alice, Forshew, Tim, Carvalho, Diana, Marshall, Lynley V, Qin, Elizabeth Y, Ingram, Wendy J, Moore, Andrew S, Ng, Ho-Keung, Trabelsi, Saoussen, Brahim, Dorra H’mida-Ben, Entz-Werle, Natacha, Zacharoulis, Stergios, Vaidya, Sucheta, Mandeville, Henry C, Bridges, Leslie R, Martin, Andrew J, Al-Sarraj, Safa, Chandler, Christopher, Sunol, Mariona, Mora, Jaume, de Torres, Carmen, Cruz, Ofelia, Carcaboso, Angel M, Monje, Michelle, Mackay, Alan, Jones, Chris
Publicado 2018

DIPG Harbors Alterations Targetable by MEK Inhibitors, with Acquired Resistance Mechanisms Overcome by Combinatorial Inhibition

por Izquierdo, Elisa, Carvalho, Diana M., Mackay, Alan, Temelso, Sara, Boult, Jessica K.R., Pericoli, Giulia, Fernandez, Elisabet, Das, Molina, Molinari, Valeria, Grabovska, Yura, Rogers, Rebecca F., Ajmone-Cat, Maria Antonietta, Proszek, Paula Z., Stubbs, Mark, Depani, Sarita, O'Hare, Patricia, Yu, Lu, Roumelioti, Georgia, Choudhary, Jyoti S., Clarke, Matthew, Fairchild, Amy R., Jacques, Thomas S., Grundy, Richard G., Howell, Lisa, Picton, Susan, Adamski, Jenny, Wilson, Shaun, Gray, Juliet C., Zebian, Bassel, Marshall, Lynley V., Carceller, Fernando, Grill, Jacques, Vinci, Maria, Robinson, Simon P., Hubank, Michael, Hargrave, Darren, Jones, Chris
Publicado 2022