Tumour-agnostic drugs in paediatric cancers

by Chisholm, Julia C., Carceller, Fernando, Marshall, Lynley V.
Published 2020

Reply to ‘Comment on “Tumour-agnostic drugs in paediatric cancers”’

by Chisholm, Julia C., Carceller, Fernando, Marshall, Lynley V.
Published 2020

Liquid biopsy for children with central nervous system tumours: Clinical integration and technical considerations

by Stankunaite, Reda, Marshall, Lynley V., Carceller, Fernando, Chesler, Louis, Hubank, Michael, George, Sally L.
Published 2022

Novel therapeutic approaches for pediatric diencephalic tumors: improving functional outcomes

by Cockle, Julia V., Corley, Elizabeth A., Zebian, Bassel, Hettige, Samantha, Vaidya, Sucheta J., Angelini, Paola, Stone, Joanna, Leitch, R Jane, Albanese, Assunta, Mandeville, Henry C., Carceller, Fernando, Marshall, Lynley V.
Published 2023

In vitro nuclear magnetic resonance spectroscopy metabolic biomarkers for the combination of temozolomide with PI3K inhibition in paediatric glioblastoma cells

by Al-Saffar, Nada M. S., Agliano, Alice, Marshall, Lynley V., Jackson, L. Elizabeth, Balarajah, Geetha, Sidhu, Jasmin, Clarke, Paul A., Jones, Chris, Workman, Paul, Pearson, Andrew D. J., Leach, Martin O.
Published 2017

Lactate and Choline Metabolites Detected In Vitro by Nuclear Magnetic Resonance Spectroscopy Are Potential Metabolic Biomarkers for PI3K Inhibition in Pediatric Glioblastoma

by Al-Saffar, Nada M. S., Marshall, Lynley V., Jackson, L. Elizabeth, Balarajah, Geetha, Eykyn, Thomas R., Agliano, Alice, Clarke, Paul A., Jones, Chris, Workman, Paul, Pearson, Andrew D. J., Leach, Martin O.
Published 2014

Multimodal immunogenomic biomarker analysis of tumors from pediatric patients enrolled to a phase 1-2 study of single-agent atezolizumab

by Nabbi, Arash, Danesh, Arnavaz, Espin-Garcia, Osvaldo, Pedersen, Stephanie, Wellum, Johanna, Fu, Lingyan Helen, Paulson, Joseph N., Geoerger, Birgit, Marshall, Lynley V., Trippett, Tanya, Rossato, Gianluca, Pugh, Trevor J., Hutchinson, Katherine E.
Published 2023

Regorafenib plus Vincristine and Irinotecan in Pediatric Patients with Recurrent/Refractory Solid Tumors: An Innovative Therapy for Children with Cancer Study

by Casanova, Michela, Bautista, Francisco, Campbell-Hewson, Quentin, Makin, Guy, Marshall, Lynley V., Verschuur, Arnauld C., Cañete Nieto, Adela, Corradini, Nadège, Ploeger, Bart A., Brennan, Barbara J., Mueller, Udo, Zebger-Gong, Hong, Chung, John W., Geoerger, Birgit
Published 2023

Demonstration of the reproducibility of free-breathing diffusion-weighted MRI and dynamic contrast enhanced MRI in children with solid tumours: a pilot study

by Miyazaki, Keiko, Jerome, Neil P., Collins, David J., Orton, Matthew R., d’Arcy, James A., Wallace, Toni, Moreno, Lucas, Pearson, Andrew D. J., Marshall, Lynley V., Carceller, Fernando, Leach, Martin O., Zacharoulis, Stergios, Koh, Dow-Mu
Published 2015

Repeatability of derived parameters from histograms following non-Gaussian diffusion modelling of diffusion-weighted imaging in a paediatric oncological cohort

by Jerome, Neil P., Miyazaki, Keiko, Collins, David J., Orton, Matthew R., d’Arcy, James A., Wallace, Toni, Moreno, Lucas, Pearson, Andrew D. J., Marshall, Lynley V., Carceller, Fernando, Leach, Martin O., Zacharoulis, Stergios, Koh, Dow-Mu
Published 2016

Phase 2 Study of Pomalidomide (CC-4047) Monotherapy for Children and Young Adults With Recurrent or Progressive Primary Brain Tumors

by Fangusaro, Jason, Cefalo, Maria Giuseppina, Garré, Maria Luisa, Marshall, Lynley V., Massimino, Maura, Benettaib, Bouchra, Biserna, Noha, Poon, Jennifer, Quan, Jackie, Conlin, Erin, Lewandowski, John, Simcock, Mathew, Jeste, Neelum, Hargrave, Darren R., Doz, François, Warren, Katherine E.
Published 2021

Droplet digital PCR-based detection of circulating tumor DNA from pediatric high grade and diffuse midline glioma patients

by Izquierdo, Elisa, Proszek, Paula, Pericoli, Giulia, Temelso, Sara, Clarke, Matthew, Carvalho, Diana M, Mackay, Alan, Marshall, Lynley V, Carceller, Fernando, Hargrave, Darren, Lannering, Birgitta, Pavelka, Zdenek, Bailey, Simon, Entz-Werle, Natacha, Grill, Jacques, Vassal, Gilles, Rodriguez, Daniel, Morgan, Paul S, Jaspan, Tim, Mastronuzzi, Angela, Vinci, Mara, Hubank, Michael, Jones, Chris
Published 2021

Entrectinib in children and young adults with solid or primary CNS tumors harboring NTRK, ROS1, or ALK aberrations (STARTRK-NG)

by Desai, Ami V, Robinson, Giles W, Gauvain, Karen, Basu, Ellen M, Macy, Margaret E, Maese, Luke, Whipple, Nicholas S, Sabnis, Amit J, Foster, Jennifer H, Shusterman, Suzanne, Yoon, Janet, Weiss, Brian D, Abdelbaki, Mohamed S, Armstrong, Amy E, Cash, Thomas, Pratilas, Christine A, Corradini, Nadège, Marshall, Lynley V, Farid-Kapadia, Mufiza, Chohan, Saibah, Devlin, Clare, Meneses-Lorente, Georgina, Cardenas, Alison, Hutchinson, Katherine E, Bergthold, Guillaume, Caron, Hubert, Chow Maneval, Edna, Gajjar, Amar, Fox, Elizabeth
Published 2022

Enhancing reporting quality and impact of early phase dose-finding clinical trials: CONSORT Dose-finding Extension (CONSORT-DEFINE) guidance

by Yap, Christina, Solovyeva, Olga, de Bono, Johann, Rekowski, Jan, Patel, Dhrusti, Jaki, Thomas, Mander, Adrian, Evans, Thomas R Jeffry, Peck, Richard, Hayward, Kathryn S, Hopewell, Sally, Ursino, Moreno, Rantell, Khadija Rerhou, Calvert, Melanie, Lee, Shing, Kightley, Andrew, Ashby, Deborah, Chan, An-Wen, Garrett-Mayer, Elizabeth, Isaacs, John D, Golub, Robert, Kholmanskikh, Olga, Richards, Dawn, Boix, Oliver, Matcham, James, Seymour, Lesley, Ivy, S Percy, Marshall, Lynley V, Hommais, Antoine, Liu, Rong, Tanaka, Yoshiya, Berlin, Jordan, Espinasse, Aude, Dimairo, Munyaradzi, Weir, Christopher J
Published 2023

A tailored molecular profiling programme for children with cancer to identify clinically actionable genetic alterations

by George, Sally L., Izquierdo, Elisa, Campbell, James, Koutroumanidou, Eleni, Proszek, Paula, Jamal, Sabri, Hughes, Deborah, Yuan, Lina, Marshall, Lynley V., Carceller, Fernando, Chisholm, Julia C., Vaidya, Sucheta, Mandeville, Henry, Angelini, Paola, Wasti, Ajla, Bexelius, Tomas, Thway, Khin, Gatz, Susanne A., Clarke, Matthew, Al-Lazikani, Bissan, Barone, Giuseppe, Anderson, John, Tweddle, Deborah A., Gonzalez, David, Walker, Brian A., Barton, Jack, Depani, Sarita, Eze, Jessica, Ahmed, Saira W., Moreno, Lucas, Pearson, Andrew, Shipley, Janet, Jones, Chris, Hargrave, Darren, Jacques, Thomas S., Hubank, Michael, Chesler, Louis
Published 2019

Functional diversity and co-operativity between subclonal populations of paediatric glioblastoma and diffuse intrinsic pontine glioma cells

by Vinci, Mara, Burford, Anna, Molinari, Valeria, Kessler, Ketty, Popov, Sergey, Clarke, Matthew, Taylor, Kathryn R, Pemberton, Helen, Lord, Christopher J, Gutteridge, Alice, Forshew, Tim, Carvalho, Diana, Marshall, Lynley V, Qin, Elizabeth Y, Ingram, Wendy J, Moore, Andrew S, Ng, Ho-Keung, Trabelsi, Saoussen, Brahim, Dorra H’mida-Ben, Entz-Werle, Natacha, Zacharoulis, Stergios, Vaidya, Sucheta, Mandeville, Henry C, Bridges, Leslie R, Martin, Andrew J, Al-Sarraj, Safa, Chandler, Christopher, Sunol, Mariona, Mora, Jaume, de Torres, Carmen, Cruz, Ofelia, Carcaboso, Angel M, Monje, Michelle, Mackay, Alan, Jones, Chris
Published 2018

DIPG Harbors Alterations Targetable by MEK Inhibitors, with Acquired Resistance Mechanisms Overcome by Combinatorial Inhibition

by Izquierdo, Elisa, Carvalho, Diana M., Mackay, Alan, Temelso, Sara, Boult, Jessica K.R., Pericoli, Giulia, Fernandez, Elisabet, Das, Molina, Molinari, Valeria, Grabovska, Yura, Rogers, Rebecca F., Ajmone-Cat, Maria Antonietta, Proszek, Paula Z., Stubbs, Mark, Depani, Sarita, O'Hare, Patricia, Yu, Lu, Roumelioti, Georgia, Choudhary, Jyoti S., Clarke, Matthew, Fairchild, Amy R., Jacques, Thomas S., Grundy, Richard G., Howell, Lisa, Picton, Susan, Adamski, Jenny, Wilson, Shaun, Gray, Juliet C., Zebian, Bassel, Marshall, Lynley V., Carceller, Fernando, Grill, Jacques, Vinci, Maria, Robinson, Simon P., Hubank, Michael, Hargrave, Darren, Jones, Chris
Published 2022